3NE2

Archaeoglobus fulgidus aquaporin

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Membrane Protein Annotation: OPM
Membrane Protein Annotation: PDBTM
Membrane Protein Annotation: MemProtMD

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d3ne2a_	Membrane and cell surface proteins and peptides	Aquaporin-like	Aquaporin-like	automated matches	automated matches	(Archaeoglobus fulgidus ) [TaxId: 2234 ],	SCOPe (2.08)
B	d3ne2b_	Membrane and cell surface proteins and peptides	Aquaporin-like	Aquaporin-like	automated matches	automated matches	(Archaeoglobus fulgidus ) [TaxId: 2234 ],	SCOPe (2.08)
C	d3ne2c_	Membrane and cell surface proteins and peptides	Aquaporin-like	Aquaporin-like	automated matches	automated matches	(Archaeoglobus fulgidus ) [TaxId: 2234 ],	SCOPe (2.08)
D	d3ne2d_	Membrane and cell surface proteins and peptides	Aquaporin-like	Aquaporin-like	automated matches	automated matches	(Archaeoglobus fulgidus ) [TaxId: 2234 ],	SCOPe (2.08)
E	d3ne2e_	Membrane and cell surface proteins and peptides	Aquaporin-like	Aquaporin-like	automated matches	automated matches	(Archaeoglobus fulgidus ) [TaxId: 2234 ],	SCOPe (2.08)
F	d3ne2f_	Membrane and cell surface proteins and peptides	Aquaporin-like	Aquaporin-like	automated matches	automated matches	(Archaeoglobus fulgidus ) [TaxId: 2234 ],	SCOPe (2.08)
G	d3ne2g_	Membrane and cell surface proteins and peptides	Aquaporin-like	Aquaporin-like	automated matches	automated matches	(Archaeoglobus fulgidus ) [TaxId: 2234 ],	SCOPe (2.08)
H	d3ne2h_	Membrane and cell surface proteins and peptides	Aquaporin-like	Aquaporin-like	automated matches	automated matches	(Archaeoglobus fulgidus ) [TaxId: 2234 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Aquaporin-like	8076110	4003025	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Aquaporin-like	8076111	3000508	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	Aquaporin-like	8076111	3000508	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Aquaporin-like	8076111	3000508	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Aquaporin-like	8076111	3000508	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	Aquaporin-like	8076111	3000508	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	Aquaporin-like	8076111	3000508	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	Aquaporin-like	8076111	3000508	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	Aquaporin-like	8076111	3000508	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF00230	e3ne2A1	A: alpha complex topology	X: Aquaporin-like (From Topology)	H: Aquaporin-like (From Topology)	T: Aquaporin-like	F: PF00230	ECOD (1.6)
B	PF00230	e3ne2B1	A: alpha complex topology	X: Aquaporin-like (From Topology)	H: Aquaporin-like (From Topology)	T: Aquaporin-like	F: PF00230	ECOD (1.6)
C	PF00230	e3ne2C1	A: alpha complex topology	X: Aquaporin-like (From Topology)	H: Aquaporin-like (From Topology)	T: Aquaporin-like	F: PF00230	ECOD (1.6)
D	PF00230	e3ne2D1	A: alpha complex topology	X: Aquaporin-like (From Topology)	H: Aquaporin-like (From Topology)	T: Aquaporin-like	F: PF00230	ECOD (1.6)
E	PF00230	e3ne2E1	A: alpha complex topology	X: Aquaporin-like (From Topology)	H: Aquaporin-like (From Topology)	T: Aquaporin-like	F: PF00230	ECOD (1.6)
F	PF00230	e3ne2F1	A: alpha complex topology	X: Aquaporin-like (From Topology)	H: Aquaporin-like (From Topology)	T: Aquaporin-like	F: PF00230	ECOD (1.6)
G	PF00230	e3ne2G1	A: alpha complex topology	X: Aquaporin-like (From Topology)	H: Aquaporin-like (From Topology)	T: Aquaporin-like	F: PF00230	ECOD (1.6)
H	PF00230	e3ne2H1	A: alpha complex topology	X: Aquaporin-like (From Topology)	H: Aquaporin-like (From Topology)	T: Aquaporin-like	F: PF00230	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.20.1080.10	Mainly Alpha	Up-down Bundle	Glycerol uptake facilitator protein	Glycerol uptake facilitator protein.	CATH (4.3.0)
B	1.20.1080.10	Mainly Alpha	Up-down Bundle	Glycerol uptake facilitator protein	Glycerol uptake facilitator protein.	CATH (4.3.0)
C	1.20.1080.10	Mainly Alpha	Up-down Bundle	Glycerol uptake facilitator protein	Glycerol uptake facilitator protein.	CATH (4.3.0)
D	1.20.1080.10	Mainly Alpha	Up-down Bundle	Glycerol uptake facilitator protein	Glycerol uptake facilitator protein.	CATH (4.3.0)
E	1.20.1080.10	Mainly Alpha	Up-down Bundle	Glycerol uptake facilitator protein	Glycerol uptake facilitator protein.	CATH (4.3.0)
F	1.20.1080.10	Mainly Alpha	Up-down Bundle	Glycerol uptake facilitator protein	Glycerol uptake facilitator protein.	CATH (4.3.0)
G	1.20.1080.10	Mainly Alpha	Up-down Bundle	Glycerol uptake facilitator protein	Glycerol uptake facilitator protein.	CATH (4.3.0)
H	1.20.1080.10	Mainly Alpha	Up-down Bundle	Glycerol uptake facilitator protein	Glycerol uptake facilitator protein.	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F, G, H	PF00230	Major intrinsic protein (MIP)	Major intrinsic protein	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F, G, H	Probable aquaporin AqpM	passive transmembrane transporter activity channel activity transporter activity transmembrane transporter activity	-	cell periphery plasma membrane membrane cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F, G, H	IPR022357	Major intrinsic protein, conserved site	Conserved Site
A, B, C, D, E A, B, C, D, E, F, G, H	IPR034294	Aquaporin transporter	Family
A, B, C, D, E A, B, C, D, E, F, G, H	IPR023271	Aquaporin-like	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G, H	IPR000425	Major intrinsic protein	Family

Membrane Protein Annotation: OPM OPM Database Homepage

Chains	External Link	Type	Class	Superfamily	Family
A, B, C, D, E A, B, C, D, E, F, G, H	OPM	Transmembrane	Alpha-helical polytopic	Major Intrinsic Protein (MIP)/FNT superfamily	Major intrinsic protein (MIP) family

Membrane Protein Annotation: PDBTM PDBTM Database Homepage

Chains	External Link	Comment
A, B, C, D, E A, B, C, D, E, F, G, H	PDBTM	Annotated as membrane protein by PDBTM

Membrane Protein Annotation: MemProtMD MemProtMD Database Homepage

Chains	External Link	Comment
A, B, C, D, E A, B, C, D, E, F, G, H	MemProtMD	Annotated as membrane protein by MemProtMD

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.