3MH8

Crystal structure of LprG from Mycobacterium tuberculosis

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
B	d3mh8b_	All beta proteins	LolA-like prokaryotic lipoproteins and lipoprotein localization factors	Prokaryotic lipoproteins and lipoprotein localization factors	automated matches	automated matches	(Mycobacterium tuberculosis H37Rv ) [TaxId: 83332 ],	SCOPe (2.08)
A	d3mh8a_	All beta proteins	LolA-like prokaryotic lipoproteins and lipoprotein localization factors	Prokaryotic lipoproteins and lipoprotein localization factors	automated matches	automated matches	(Mycobacterium tuberculosis H37Rv ) [TaxId: 83332 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
B	SCOP2B Superfamily	LolA-like	8083937	3001964	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	LolA-like	8083937	3001964	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
B	PF07161	e3mh8B1	A: beta meanders	X: Lipoprotein localization factors LolAB	H: Lipoprotein localization factors LolAB (From Topology)	T: Lipoprotein localization factors LolAB	F: PF07161	ECOD (1.6)
A	PF07161	e3mh8A1	A: beta meanders	X: Lipoprotein localization factors LolAB	H: Lipoprotein localization factors LolAB (From Topology)	T: Lipoprotein localization factors LolAB	F: PF07161	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
B	2.50.20.20	Mainly Beta	Clam	outer membrane lipoprotein receptor (LolB), chain A		CATH (4.3.0)
A	2.50.20.20	Mainly Beta	Clam	outer membrane lipoprotein receptor (LolB), chain A		CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF07161	LppX_LprAFG lipoprotein (LppX_LprAFG)	LppX_LprAFG lipoprotein	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Lipoprotein lprG	binding phospholipid binding lipid binding phosphatidylinositol binding glycolipid binding carbohydrate derivative binding	localization transport macromolecule localization organic substance transport lipid localization lipid transport establishment of localization response to stimulus response to chemical response to antibiotic	cell surface cellular anatomical entity intracellular anatomical structure cytoplasm cytosol cell periphery plasma membrane membrane membrane-bounded organelle extracellular vesicle extracellular organelle extracellular region organelle bacterial extracellular vesicle cell surface cellular anatomical entity intracellular anatomical structure cytoplasm cytosol cell periphery plasma membrane membrane membrane-bounded organelle extracellular vesicle extracellular organelle extracellular region organelle bacterial extracellular vesicle vesicle extracellular membrane-bounded organelle external encapsulating structure cell wall peptidoglycan-based cell wall

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR009830	LppX/LprAFG lipoprotein family	Family
A, B	IPR029046	Lipoprotein localisation LolA/LolB/LppX	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.