3LWF

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Rrf2	e3lwfA1	A: alpha arrays	X: HTH	H: HTH	T: winged	F: Rrf2	ECOD (1.6)
B	Rrf2	e3lwfB1	A: alpha arrays	X: HTH	H: HTH	T: winged	F: Rrf2	ECOD (1.6)
C	Rrf2	e3lwfC1	A: alpha arrays	X: HTH	H: HTH	T: winged	F: Rrf2	ECOD (1.6)
D	Rrf2	e3lwfD1	A: alpha arrays	X: HTH	H: HTH	T: winged	F: Rrf2	ECOD (1.6)

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.10.10.10	Mainly Alpha	Orthogonal Bundle	Arc Repressor Mutant, subunit A	Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	CATH (4.3.0)
B	1.10.10.10	Mainly Alpha	Orthogonal Bundle	Arc Repressor Mutant, subunit A	Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	CATH (4.3.0)
C	1.10.10.10	Mainly Alpha	Orthogonal Bundle	Arc Repressor Mutant, subunit A	Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	CATH (4.3.0)
D	1.10.10.10	Mainly Alpha	Orthogonal Bundle	Arc Repressor Mutant, subunit A	Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	CATH (4.3.0)

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF02082	Iron-dependent Transcriptional regulator (Rrf2)	Iron-dependent Transcriptional regulator	Several proteins in this family form iron-sulfur clusters enabling iron dependent DNA transcription regulation [1]. The iron binding is mediated by three conserved cysteine residues. Members of this family can also bind O-acetyl-L-serine, [Fe-S] and ...	Several proteins in this family form iron-sulfur clusters enabling iron dependent DNA transcription regulation [1]. The iron binding is mediated by three conserved cysteine residues. Members of this family can also bind O-acetyl-L-serine, [Fe-S] and nitric oxide (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).	Domain

Chains	Accession	Name	Type
A, B, C, D	IPR030489	Transcription regulator Rrf2-type, conserved site	Conserved Site
A, B, C, D	IPR036388	Winged helix-like DNA-binding domain superfamily	Homologous Superfamily
A, B, C, D	IPR000944	Transcription regulator Rrf2	Family
A, B, C, D	IPR036390	Winged helix DNA-binding domain superfamily	Homologous Superfamily