Annotations: 3KFK

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Cpn60_TCP1_1st	e3kfkA5	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: Cpn60_TCP1_1st	ECOD (1.6)
A	Cpn60_TCP1_2nd	e3kfkA4	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: Cpn60_TCP1_2nd	ECOD (1.6)
A	Cpn60_TCP1_2nd_1	e3kfkA6	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: Cpn60_TCP1_2nd_1	ECOD (1.6)
B	Cpn60_TCP1_1st	e3kfkB5	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: Cpn60_TCP1_1st	ECOD (1.6)
B	Cpn60_TCP1_2nd	e3kfkB4	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: Cpn60_TCP1_2nd	ECOD (1.6)
B	Cpn60_TCP1_2nd_1	e3kfkB6	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: Cpn60_TCP1_2nd_1	ECOD (1.6)
C	Cpn60_TCP1_1st	e3kfkC5	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: Cpn60_TCP1_1st	ECOD (1.6)
C	Cpn60_TCP1_2nd	e3kfkC4	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: Cpn60_TCP1_2nd	ECOD (1.6)
C	Cpn60_TCP1_2nd_1	e3kfkC6	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: Cpn60_TCP1_2nd_1	ECOD (1.6)
D	Cpn60_TCP1_1st	e3kfkD5	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: Cpn60_TCP1_1st	ECOD (1.6)
D	Cpn60_TCP1_2nd	e3kfkD4	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: Cpn60_TCP1_2nd	ECOD (1.6)
D	Cpn60_TCP1_2nd_1	e3kfkD6	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: Cpn60_TCP1_2nd_1	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF00118	TCP-1/cpn60 chaperonin family (Cpn60_TCP1)	TCP-1/cpn60 chaperonin family	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	Chaperonin	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding pyrophosphatase activity ATP hydrolysis activity ribonucleoside triphosphate phosphatase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides hydrolase activity hydrolase activity, acting on acid anhydrides catalytic activity ATP-dependent activity unfolded protein binding protein binding ATP-dependent protein folding chaperone protein folding chaperone identical protein binding	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D	IPR027413	GroEL-like equatorial domain superfamily	Homologous Superfamily
A, B, C, D	IPR017998	Chaperone tailless complex polypeptide 1 (TCP-1)	Family
A, B, C, D	IPR027410	TCP-1-like chaperonin intermediate domain superfamily	Homologous Superfamily
A, B, C, D	IPR002194	Chaperonin TCP-1, conserved site	Conserved Site
A, B, C, D	IPR027409	GroEL-like apical domain superfamily	Homologous Superfamily
A, B, C, D	IPR012714	Thermosome, archaeal	Family
A, B, C, D	IPR002423	Chaperonin Cpn60/GroEL/TCP-1 family	Family

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.