3JWN

Complex of FimC, FimF, FimG and FimH

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A [auth C]	d3jwnc1	All beta proteins	Immunoglobulin-like beta-sandwich	PapD-like	Pilus chaperone	Periplasmic chaperone FimC	(Escherichia coli K-12 ) [TaxId: 83333 ],	SCOPe (2.08)
A [auth C]	d3jwnc2	All beta proteins	C2 domain-like	Periplasmic chaperone C-domain	Periplasmic chaperone C-domain	FimC	(Escherichia coli K-12 ) [TaxId: 83333 ],	SCOPe (2.08)
F [auth I]	d3jwni1	All beta proteins	Immunoglobulin-like beta-sandwich	PapD-like	Pilus chaperone	Periplasmic chaperone FimC	(Escherichia coli K-12 ) [TaxId: 83333 ],	SCOPe (2.08)
F [auth I]	d3jwni2	All beta proteins	C2 domain-like	Periplasmic chaperone C-domain	Periplasmic chaperone C-domain	FimC	(Escherichia coli K-12 ) [TaxId: 83333 ],	SCOPe (2.08)
B [auth E]	d3jwne_	All beta proteins	Common fold of diphtheria toxin/transcription factors/cytochrome f	Bacterial adhesins	automated matches	automated matches	(Escherichia coli K-12 ) [TaxId: 83333 ],	SCOPe (2.08)
C [auth F]	d3jwnf_	All beta proteins	Common fold of diphtheria toxin/transcription factors/cytochrome f	Bacterial adhesins	automated matches	automated matches	(Escherichia coli K-12 ) [TaxId: 83333 ],	SCOPe (2.08)
G [auth K]	d3jwnk_	All beta proteins	Common fold of diphtheria toxin/transcription factors/cytochrome f	Bacterial adhesins	automated matches	automated matches	(Escherichia coli K-12 ) [TaxId: 83333 ],	SCOPe (2.08)
H [auth L]	d3jwnl_	All beta proteins	Common fold of diphtheria toxin/transcription factors/cytochrome f	Bacterial adhesins	automated matches	automated matches	(Escherichia coli K-12 ) [TaxId: 83333 ],	SCOPe (2.08)
E [auth H]	d3jwnh1	All beta proteins	Common fold of diphtheria toxin/transcription factors/cytochrome f	Bacterial adhesins	Pilus subunits	automated matches	(Escherichia coli F18+ ) [TaxId: 488477 ],	SCOPe (2.08)
J [auth N]	d3jwnn1	All beta proteins	Common fold of diphtheria toxin/transcription factors/cytochrome f	Bacterial adhesins	Pilus subunits	automated matches	(Escherichia coli F18+ ) [TaxId: 488477 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A [auth C]	SCOP2B Superfamily	Periplasmic chaperone C-domain	8035665	3000998	SCOP2B (2022-06-29)
A [auth C]	SCOP2B Superfamily	PapD-like	8055315	3002067	SCOP2B (2022-06-29)
F [auth I]	SCOP2B Superfamily	Periplasmic chaperone C-domain	8035665	3000998	SCOP2B (2022-06-29)
F [auth I]	SCOP2B Superfamily	PapD-like	8055315	3002067	SCOP2B (2022-06-29)
B [auth E]	SCOP2B Superfamily	Bacterial adhesin-like	8098308	3000723	SCOP2B (2022-06-29)
C [auth F]	SCOP2 Family	Pilus subunits	8098307	4002034	SCOP2 (2022-06-29)
C [auth F]	SCOP2 Superfamily	Bacterial adhesin-like	8098308	3000723	SCOP2 (2022-06-29)
G [auth K]	SCOP2B Superfamily	Bacterial adhesin-like	8098308	3000723	SCOP2B (2022-06-29)
H [auth L]	SCOP2B Superfamily	Bacterial adhesin-like	8098308	3000723	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A [auth C]	PapD_C	e3jwnC1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: PapD_C	ECOD (1.6)
A [auth C]	PapD_N	e3jwnC2	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: PapD_N	ECOD (1.6)
F [auth I]	PapD_C	e3jwnI1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: PapD_C	ECOD (1.6)
F [auth I]	PapD_N	e3jwnI2	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: PapD_N	ECOD (1.6)
B [auth E]	Fimbrial_1	e3jwnE1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Common fold of diphtheria toxin/transcription factors/cytochrome f	F: Fimbrial_1	ECOD (1.6)
C [auth F]	Fimbrial_1	e3jwnF1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Common fold of diphtheria toxin/transcription factors/cytochrome f	F: Fimbrial_1	ECOD (1.6)
G [auth K]	Fimbrial_1	e3jwnK1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Common fold of diphtheria toxin/transcription factors/cytochrome f	F: Fimbrial_1	ECOD (1.6)
H [auth L]	Fimbrial_1	e3jwnL1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Common fold of diphtheria toxin/transcription factors/cytochrome f	F: Fimbrial_1	ECOD (1.6)
D [auth G]	Fimbrial_1	e3jwnG1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Common fold of diphtheria toxin/transcription factors/cytochrome f	F: Fimbrial_1	ECOD (1.6)
I [auth M]	Fimbrial_1	e3jwnM1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Common fold of diphtheria toxin/transcription factors/cytochrome f	F: Fimbrial_1	ECOD (1.6)
E [auth H]	FimH_man-bind	e3jwnH1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Common fold of diphtheria toxin/transcription factors/cytochrome f	F: FimH_man-bind	ECOD (1.6)
E [auth H]	Fimbrial_1	e3jwnH2	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Common fold of diphtheria toxin/transcription factors/cytochrome f	F: Fimbrial_1	ECOD (1.6)
J [auth N]	FimH_man-bind	e3jwnN1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Common fold of diphtheria toxin/transcription factors/cytochrome f	F: FimH_man-bind	ECOD (1.6)
J [auth N]	Fimbrial_1	e3jwnN2	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Common fold of diphtheria toxin/transcription factors/cytochrome f	F: Fimbrial_1	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A [auth C]	2.60.40.10	Mainly Beta	Sandwich	Immunoglobulin-like	Immunoglobulins	CATH (4.3.0)
F [auth I]	2.60.40.10	Mainly Beta	Sandwich	Immunoglobulin-like	Immunoglobulins	CATH (4.3.0)
B [auth E]	2.60.40.1090	Mainly Beta	Sandwich	Immunoglobulin-like	Fimbrial-type adhesion domain	CATH (4.3.0)
C [auth F]	2.60.40.1090	Mainly Beta	Sandwich	Immunoglobulin-like	Fimbrial-type adhesion domain	CATH (4.3.0)
G [auth K]	2.60.40.1090	Mainly Beta	Sandwich	Immunoglobulin-like	Fimbrial-type adhesion domain	CATH (4.3.0)
H [auth L]	2.60.40.1090	Mainly Beta	Sandwich	Immunoglobulin-like	Fimbrial-type adhesion domain	CATH (4.3.0)
D [auth G]	2.60.40.1090	Mainly Beta	Sandwich	Immunoglobulin-like	Fimbrial-type adhesion domain	CATH (4.3.0)
I [auth M]	2.60.40.1090	Mainly Beta	Sandwich	Immunoglobulin-like	Fimbrial-type adhesion domain	CATH (4.3.0)
E [auth H]	2.60.40.1090	Mainly Beta	Sandwich	Immunoglobulin-like	Fimbrial-type adhesion domain	CATH (4.3.0)
J [auth N]	2.60.40.1090	Mainly Beta	Sandwich	Immunoglobulin-like	Fimbrial-type adhesion domain	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A [auth C], F [auth I]	PF02753	Pili assembly chaperone PapD, C-terminal domain (PapD_C)	Pili assembly chaperone PapD, C-terminal domain	Ig-like beta-sandwich fold. This domain is the C-terminal part of the pilus and flagellar-assembly chaperone protein PapD.	Domain
A [auth C], F [auth I]	PF00345	Pili and flagellar-assembly chaperone, PapD N-terminal domain (PapD_N)	Pili and flagellar-assembly chaperone, PapD N-terminal domain	C2 domain-like beta-sandwich fold. This domain is the n-terminal part of the PapD chaperone protein for pilus and flagellar assembly.	Domain
B [auth E], C [auth F], G [auth K], H [auth L]	PF00419	Fimbrial protein (Fimbrial)	Fimbrial protein	-	Domain
E [auth H], J [auth N]	PF00419	Fimbrial protein (Fimbrial)	Fimbrial protein	-	Domain
E [auth H], J [auth N]	PF09160	FimH, mannose binding (FimH_man-bind)	FimH, mannose binding	Members of this family adopt a secondary structure consisting of a beta sandwich, with nine strands arranged in two sheets in a Greek key topology. They are predominantly found in bacterial mannose-specific adhesins, since they are capable of binding ...	Members of this family adopt a secondary structure consisting of a beta sandwich, with nine strands arranged in two sheets in a Greek key topology. They are predominantly found in bacterial mannose-specific adhesins, since they are capable of binding to D-mannose [1].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth C], F [auth I]	Chaperone protein fimC	protein folding chaperone	cellular component organization cell wall organization or biogenesis cell wall organization cellular process cellular component organization or biogenesis external encapsulating structure organization organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process primary metabolic process gene expression chaperone-mediated protein folding macromolecule biosynthetic process protein maturation cellular component organization cell wall organization or biogenesis cell wall organization cellular process cellular component organization or biogenesis external encapsulating structure organization organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process primary metabolic process gene expression chaperone-mediated protein folding macromolecule biosynthetic process protein maturation organic substance metabolic process protein folding biosynthetic process organic substance biosynthetic process metabolic process protein metabolic process macromolecule metabolic process	outer membrane-bounded periplasmic space cell envelope periplasmic space cellular anatomical entity
B [auth E], C [auth F], G [auth K], H [auth L]	Protein fimF	-	behavior multicellular organismal process response to stimulus response to mechanical stimulus response to abiotic stimulus response to external stimulus mechanosensory behavior cell adhesion cell-substrate adhesion cellular process cell adhesion involved in biofilm formation cell aggregation biofilm formation biological process involved in intraspecies interaction between organisms behavior multicellular organismal process response to stimulus response to mechanical stimulus response to abiotic stimulus response to external stimulus mechanosensory behavior cell adhesion cell-substrate adhesion cellular process cell adhesion involved in biofilm formation cell aggregation biofilm formation biological process involved in intraspecies interaction between organisms single-species biofilm formation aggregation of unicellular organisms submerged biofilm formation cell adhesion involved in single-species biofilm formation single-species submerged biofilm formation	pilus cell projection cellular anatomical entity pilus tip
D [auth G], I [auth M]	Protein fimG	-	behavior multicellular organismal process response to stimulus response to mechanical stimulus response to abiotic stimulus response to external stimulus mechanosensory behavior cell adhesion cell-substrate adhesion cellular process cell adhesion involved in biofilm formation cell aggregation biofilm formation biological process involved in intraspecies interaction between organisms behavior multicellular organismal process response to stimulus response to mechanical stimulus response to abiotic stimulus response to external stimulus mechanosensory behavior cell adhesion cell-substrate adhesion cellular process cell adhesion involved in biofilm formation cell aggregation biofilm formation biological process involved in intraspecies interaction between organisms single-species biofilm formation aggregation of unicellular organisms submerged biofilm formation cell adhesion involved in single-species biofilm formation single-species submerged biofilm formation	pilus cell projection cellular anatomical entity pilus tip
E [auth H], J [auth N]	FimH protein	-	cell adhesion cellular process	pilus cell projection cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A [auth C], F [auth I]	IPR036316	Pili assembly chaperone, C-terminal domain superfamily	Homologous Superfamily
A [auth C], F [auth I]	IPR013783	Immunoglobulin-like fold	Homologous Superfamily
A [auth C], F [auth I]	IPR016148	Pili assembly chaperone, C-terminal	Domain
A [auth C], F [auth I]	IPR008962	PapD-like superfamily	Homologous Superfamily
A [auth C], F [auth I]	IPR016147	Pili assembly chaperone, N-terminal	Domain
A [auth C], F [auth I]	IPR001829	Pili assembly chaperone, bacterial	Family
A [auth C], F [auth I]	IPR018046	Pili assembly chaperone, conserved site	Conserved Site
B [auth E], C [auth F], G [auth K], H [auth L]	IPR000259	Fimbrial-type adhesion domain	Domain
B [auth E], C [auth F], G [auth K], H [auth L]	IPR036937	Fimbrial-type adhesion domain superfamily	Homologous Superfamily
B [auth E], C [auth F], G [auth K], H [auth L]	IPR008966	Adhesion domain superfamily	Homologous Superfamily
D [auth G], I [auth M]	IPR036937	Fimbrial-type adhesion domain superfamily	Homologous Superfamily
D [auth G], I [auth M]	IPR008966	Adhesion domain superfamily	Homologous Superfamily
E [auth H], J [auth N]	IPR000259	Fimbrial-type adhesion domain	Domain
E [auth H], J [auth N]	IPR036937	Fimbrial-type adhesion domain superfamily	Homologous Superfamily
E [auth H], J [auth N]	IPR015243	FimH, mannose-binding domain	Domain
E [auth H], J [auth N]	IPR008966	Adhesion domain superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.