3JUY

Crystal Structure of a 3B3 Variant, a Broadly Neutralizing HIV-1 scFv Antibody

External Resource: Annotation


Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
A [auth B]d3juyb1 All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin automated matches automated matches human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
B [auth A]d3juya1 All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin automated matches automated matches human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Cd3juyc1 All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin automated matches automated matches human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
D [auth E]d3juye1 All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin automated matches automated matches human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
F [auth D]d3juyd1 All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin automated matches automated matches human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
E [auth F]d3juyf1 All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin automated matches automated matches human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
A [auth B]PF07686e3juyB2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: PF07686ECOD (1.6)
B [auth A]PF07686e3juyA2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: PF07686ECOD (1.6)
CPF07686e3juyC2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: PF07686ECOD (1.6)
D [auth E]PF07686e3juyE2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: PF07686ECOD (1.6)
F [auth D]PF07686e3juyD2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: PF07686ECOD (1.6)
E [auth F]PF07686e3juyF2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: PF07686ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A [auth B]2.60.40.10 Mainly Beta Sandwich Immunoglobulin-like ImmunoglobulinsCATH (4.3.0)
B [auth A]2.60.40.10 Mainly Beta Sandwich Immunoglobulin-like ImmunoglobulinsCATH (4.3.0)
C2.60.40.10 Mainly Beta Sandwich Immunoglobulin-like ImmunoglobulinsCATH (4.3.0)
D [auth E]2.60.40.10 Mainly Beta Sandwich Immunoglobulin-like ImmunoglobulinsCATH (4.3.0)
F [auth D]2.60.40.10 Mainly Beta Sandwich Immunoglobulin-like ImmunoglobulinsCATH (4.3.0)
E [auth F]2.60.40.10 Mainly Beta Sandwich Immunoglobulin-like ImmunoglobulinsCATH (4.3.0)

IMGT Antibody Annotation IMGT Database Homepage

ChainProtein NameDescriptionOrganism NameGene Allele Name(s)Domain Name(s)Receptor TypeReceptor DescriptionProvenance Source
3B3, anti-gp120 [HIV-1], neutralizing SCFV-HEAVY-KAPPA Homo sapiens (human) IGHV1-3*01, IGHJ6*03, IGKV3-20*01, IGKJ2*01 V-DOMAIN VH, V-DOMAIN V-KAPPA IG SCFV-HEAVY-KAPPA IMGT (202416-0)