3JU3

Crystal structure of alpha chain of probable 2-oxoacid ferredoxin oxidoreductase from Thermoplasma acidophilum

External Resource: Annotation

Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF17147	e3ju3A1	A: a/b three-layered sandwiches	X: TK C-terminal domain-like (From Topology)	H: TK C-terminal domain-like (From Topology)	T: TK C-terminal domain-like	F: PF17147	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.50.920	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold		CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF17147	Pyruvate:ferredoxin oxidoreductase core domain II (PFOR_II)	Pyruvate:ferredoxin oxidoreductase core domain II	PFOR_II is a core domain of the anaerobic enzyme pyruvate:ferredoxin oxidoreductase and is necessary for inter subunit contacts in conjunction with domains I and IV [1,2].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Probable 2-oxoacid ferredoxin oxidoreductase, alpha chain	oxidoreductase activity oxidoreductase activity, acting on the aldehyde or oxo group of donors catalytic activity	sulfur compound biosynthetic process biosynthetic process cellular biosynthetic process cellular metabolic process sulfur compound metabolic process metabolic process cellular process organic substance metabolic process small molecule metabolic process organic acid metabolic process organic substance biosynthetic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR002869	Pyruvate-flavodoxin oxidoreductase, central domain	Homologous Superfamily
A	IPR033412	Pyruvate:ferredoxin oxidoreductase, core domain II	Domain
A	IPR022367	2-oxoacid:acceptor oxidoreductase, alpha subunit	Family
A	IPR029061	Thiamin diphosphate-binding fold	Homologous Superfamily
A	IPR009014	Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II	Homologous Superfamily
A	IPR019752	Pyruvate/ketoisovalerate oxidoreductase, catalytic domain	Domain
A	IPR002880	Pyruvate flavodoxin/ferredoxin oxidoreductase, pyrimidine binding domain	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.