3JTO

Crystal structure of the c-terminal domain of YpbH

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Adapter protein MecA C-terminal domain-like	8092884	3002637	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Adapter protein MecA C-terminal domain-like	8092884	3002637	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Adapter protein MecA C-terminal domain-like	8092884	3002637	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Adapter protein MecA C-terminal domain-like	8092884	3002637	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	Adapter protein MecA C-terminal domain-like	8092884	3002637	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	Adapter protein MecA C-terminal domain-like	8092884	3002637	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF05389	e3jtoA1	A: a+b two layers	X: Alpha-beta plaits	H: Adapter protein mecA 2 C-terminal domain (From Topology)	T: Adapter protein mecA 2 C-terminal domain	F: PF05389	ECOD (1.6)
B	PF05389	e3jtoB1	A: a+b two layers	X: Alpha-beta plaits	H: Adapter protein mecA 2 C-terminal domain (From Topology)	T: Adapter protein mecA 2 C-terminal domain	F: PF05389	ECOD (1.6)
C	PF05389	e3jtoC1	A: a+b two layers	X: Alpha-beta plaits	H: Adapter protein mecA 2 C-terminal domain (From Topology)	T: Adapter protein mecA 2 C-terminal domain	F: PF05389	ECOD (1.6)
D	PF05389	e3jtoD1	A: a+b two layers	X: Alpha-beta plaits	H: Adapter protein mecA 2 C-terminal domain (From Topology)	T: Adapter protein mecA 2 C-terminal domain	F: PF05389	ECOD (1.6)
E	PF05389	e3jtoE1	A: a+b two layers	X: Alpha-beta plaits	H: Adapter protein mecA 2 C-terminal domain (From Topology)	T: Adapter protein mecA 2 C-terminal domain	F: PF05389	ECOD (1.6)
F	PF05389	e3jtoF1	A: a+b two layers	X: Alpha-beta plaits	H: Adapter protein mecA 2 C-terminal domain (From Topology)	T: Adapter protein mecA 2 C-terminal domain	F: PF05389	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.30.70.1950	Alpha Beta	2-Layer Sandwich	Alpha-Beta Plaits		CATH (4.3.0)
B	3.30.70.1950	Alpha Beta	2-Layer Sandwich	Alpha-Beta Plaits		CATH (4.3.0)
C	3.30.70.1950	Alpha Beta	2-Layer Sandwich	Alpha-Beta Plaits		CATH (4.3.0)
D	3.30.70.1950	Alpha Beta	2-Layer Sandwich	Alpha-Beta Plaits		CATH (4.3.0)
E	3.30.70.1950	Alpha Beta	2-Layer Sandwich	Alpha-Beta Plaits		CATH (4.3.0)
F	3.30.70.1950	Alpha Beta	2-Layer Sandwich	Alpha-Beta Plaits		CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F	PF05389	Negative regulator of genetic competence (MecA) (MecA)	Negative regulator of genetic competence (MecA)	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F	Adapter protein mecA 2	protein-macromolecule adaptor activity molecular adaptor activity	DNA-mediated transformation cellular response to stimulus horizontal gene transfer response to stimulus establishment of competence for transformation cellular process regulation of biological process regulation of cellular process negative regulation of establishment of competence for transformation negative regulation of response to stimulus biological regulation negative regulation of biological process regulation of response to stimulus regulation of establishment of competence for transformation DNA-mediated transformation cellular response to stimulus horizontal gene transfer response to stimulus establishment of competence for transformation cellular process regulation of biological process regulation of cellular process negative regulation of establishment of competence for transformation negative regulation of response to stimulus biological regulation negative regulation of biological process regulation of response to stimulus regulation of establishment of competence for transformation negative regulation of cellular process sporulation resulting in formation of a cellular spore developmental process anatomical structure morphogenesis anatomical structure formation involved in morphogenesis anatomical structure development sporulation regulation of developmental process negative regulation of sporulation resulting in formation of a cellular spore negative regulation of developmental process negative regulation of sporulation regulation of sporulation resulting in formation of a cellular spore regulation of sporulation	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F	IPR008681	Negative regulator of genetic competence, MecA	Family
A, B, C, D, E A, B, C, D, E, F	IPR038471	MecA, C-terminal domain superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.