3IA8
The structure of the C-terminal heme nitrobindin domain of THAP domain-containing protein 4 from Homo sapiens
External Resource: Annotation
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | d3ia8a_ | All beta proteins | Lipocalins | Lipocalins | automated matches | automated matches | human (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
B | d3ia8b_ | All beta proteins | Lipocalins | Lipocalins | automated matches | automated matches | human (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | DUF1794 | e3ia8A1 | A: beta barrels | X: Lipocalins/Streptavidin | H: Lipocalins (From Topology) | T: Lipocalins | F: DUF1794 | ECOD (1.6) |
B | DUF1794 | e3ia8B1 | A: beta barrels | X: Lipocalins/Streptavidin | H: Lipocalins (From Topology) | T: Lipocalins | F: DUF1794 | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 2.40.128.20 | Mainly Beta | Beta Barrel | Lipocalin | Calycin beta-barrel core domain | CATH (4.3.0) |
B | 2.40.128.20 | Mainly Beta | Beta Barrel | Lipocalin | Calycin beta-barrel core domain | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF08768 | THAP4-like, heme-binding beta-barrel domain (THAP4_heme-bd) | THAP4-like, heme-binding beta-barrel domain | This domain can be found in THAP4 from mammals and At1g79260 from Arabidopsis. THAP4 catalyzes the heme-based conversion of peroxynitrite into nitrate-NO3- in vitro [1]. At1g79260 is a nitrophorin-like heme-binding protein that may reversibly bind ni ... | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR006612 | THAP-type zinc finger | Domain | |
IPR014878 | THAP4-like, heme-binding beta-barrel domain | Domain | |
IPR045165 | Nitrobindin family | Family | |
IPR038441 | THAP-type zinc finger superfamily | Homologous Superfamily | |
IPR012674 | Calycin | Homologous Superfamily |
Pharos: Disease Associations Pharos Homepage Annotation
Chains | Drug Target   | Associated Disease |
---|---|---|
Q8WY91 | :