3HN6

Crystal structure of glucosamine-6-phosphate deaminase from Borrelia burgdorferi

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
E	d3hn6e1	Alpha and beta proteins (a/b)	NagB/RpiA/CoA transferase-like	NagB/RpiA/CoA transferase-like	automated matches	automated matches	(Borreliella burgdorferi B31 ) [TaxId: 224326 ],	SCOPe (2.08)
E	d3hn6e2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Borreliella burgdorferi B31 ) [TaxId: 224326 ],	SCOPe (2.08)
A	d3hn6a1	Alpha and beta proteins (a/b)	NagB/RpiA/CoA transferase-like	NagB/RpiA/CoA transferase-like	automated matches	automated matches	(Borreliella burgdorferi B31 ) [TaxId: 224326 ],	SCOPe (2.08)
A	d3hn6a2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Borreliella burgdorferi B31 ) [TaxId: 224326 ],	SCOPe (2.08)
B	d3hn6b1	Alpha and beta proteins (a/b)	NagB/RpiA/CoA transferase-like	NagB/RpiA/CoA transferase-like	automated matches	automated matches	(Borreliella burgdorferi B31 ) [TaxId: 224326 ],	SCOPe (2.08)
B	d3hn6b2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Borreliella burgdorferi B31 ) [TaxId: 224326 ],	SCOPe (2.08)
C	d3hn6c1	Alpha and beta proteins (a/b)	NagB/RpiA/CoA transferase-like	NagB/RpiA/CoA transferase-like	automated matches	automated matches	(Borreliella burgdorferi B31 ) [TaxId: 224326 ],	SCOPe (2.08)
C	d3hn6c2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Borreliella burgdorferi B31 ) [TaxId: 224326 ],	SCOPe (2.08)
D	d3hn6d1	Alpha and beta proteins (a/b)	NagB/RpiA/CoA transferase-like	NagB/RpiA/CoA transferase-like	automated matches	automated matches	(Borreliella burgdorferi B31 ) [TaxId: 224326 ],	SCOPe (2.08)
D	d3hn6d2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Borreliella burgdorferi B31 ) [TaxId: 224326 ],	SCOPe (2.08)
F	d3hn6f1	Alpha and beta proteins (a/b)	NagB/RpiA/CoA transferase-like	NagB/RpiA/CoA transferase-like	automated matches	automated matches	(Borreliella burgdorferi B31 ) [TaxId: 224326 ],	SCOPe (2.08)
F	d3hn6f2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Borreliella burgdorferi B31 ) [TaxId: 224326 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
E	SCOP2B Superfamily	NagB/RpiA/CoA transferase-like	8074890	3000693	SCOP2B (2022-06-29)
A	SCOP2 Family	NagB-like	8074889	4003912	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	NagB/RpiA/CoA transferase-like	8074890	3000693	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	NagB/RpiA/CoA transferase-like	8074890	3000693	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	NagB/RpiA/CoA transferase-like	8074890	3000693	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	NagB/RpiA/CoA transferase-like	8074890	3000693	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	NagB/RpiA/CoA transferase-like	8074890	3000693	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
E	Glucosamine_iso	e3hn6E1	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: NagB/RpiA/CoA transferase-like	F: Glucosamine_iso	ECOD (1.6)
A	Glucosamine_iso	e3hn6A1	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: NagB/RpiA/CoA transferase-like	F: Glucosamine_iso	ECOD (1.6)
B	Glucosamine_iso	e3hn6B1	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: NagB/RpiA/CoA transferase-like	F: Glucosamine_iso	ECOD (1.6)
C	Glucosamine_iso	e3hn6C1	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: NagB/RpiA/CoA transferase-like	F: Glucosamine_iso	ECOD (1.6)
D	Glucosamine_iso	e3hn6D1	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: NagB/RpiA/CoA transferase-like	F: Glucosamine_iso	ECOD (1.6)
F	Glucosamine_iso	e3hn6F1	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: NagB/RpiA/CoA transferase-like	F: Glucosamine_iso	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
E	3.40.50.1360	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold		CATH (4.3.0)
A	3.40.50.1360	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold		CATH (4.3.0)
B	3.40.50.1360	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold		CATH (4.3.0)
C	3.40.50.1360	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold		CATH (4.3.0)
D	3.40.50.1360	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold		CATH (4.3.0)
F	3.40.50.1360	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold		CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F	PF01182	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase (Glucosamine_iso)	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F	Glucosamine-6-phosphate deaminase	glucosamine-6-phosphate deaminase activity hydrolase activity deaminase activity catalytic activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	carbohydrate metabolic process organic substance metabolic process primary metabolic process metabolic process amino sugar metabolic process carbohydrate derivative metabolic process N-acetylglucosamine metabolic process glucosamine-containing compound metabolic process catabolic process oxoacid metabolic process organic acid catabolic process organic acid metabolic process cellular catabolic process carboxylic acid catabolic process carbohydrate metabolic process organic substance metabolic process primary metabolic process metabolic process amino sugar metabolic process carbohydrate derivative metabolic process N-acetylglucosamine metabolic process glucosamine-containing compound metabolic process catabolic process oxoacid metabolic process organic acid catabolic process organic acid metabolic process cellular catabolic process carboxylic acid catabolic process small molecule metabolic process amide metabolic process N-acetylneuraminate metabolic process organonitrogen compound catabolic process N-acetylneuraminate catabolic process carbohydrate derivative catabolic process organonitrogen compound metabolic process cellular metabolic process carboxylic acid metabolic process amino sugar catabolic process cellular process small molecule catabolic process organic substance catabolic process	intracellular anatomical structure cytoplasm cellular anatomical entity cytosol

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F	IPR006148	Glucosamine/galactosamine-6-phosphate isomerase	Domain
A, B, C, D, E A, B, C, D, E, F	IPR004547	Glucosamine-6-phosphate isomerase	Family
A, B, C, D, E A, B, C, D, E, F	IPR018321	Glucosamine-6-phosphate isomerase, conserved site	Conserved Site
A, B, C, D, E A, B, C, D, E, F	IPR037171	NagB/RpiA transferase-like	Homologous Superfamily

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.