3HK7

Crystal structure of uronate isomerase from Bacillus halodurans complexed with zinc and D-Arabinarate, monoclinic crystal form

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d3hk7a_	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	Metallo-dependent hydrolases	Uronate isomerase-like	Uncharacterized protein BH0493	(Halalkalibacterium halodurans C-125 ) [TaxId: 272558 ],	SCOPe (2.08)
B	d3hk7b_	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	Metallo-dependent hydrolases	Uronate isomerase-like	Uncharacterized protein BH0493	(Halalkalibacterium halodurans C-125 ) [TaxId: 272558 ],	SCOPe (2.08)
C	d3hk7c_	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	Metallo-dependent hydrolases	Uronate isomerase-like	Uncharacterized protein BH0493	(Halalkalibacterium halodurans C-125 ) [TaxId: 272558 ],	SCOPe (2.08)
D	d3hk7d_	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	Metallo-dependent hydrolases	Uronate isomerase-like	Uncharacterized protein BH0493	(Halalkalibacterium halodurans C-125 ) [TaxId: 272558 ],	SCOPe (2.08)
E	d3hk7e_	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	Metallo-dependent hydrolases	Uronate isomerase-like	Uncharacterized protein BH0493	(Halalkalibacterium halodurans C-125 ) [TaxId: 272558 ],	SCOPe (2.08)
F	d3hk7f_	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	Metallo-dependent hydrolases	Uronate isomerase-like	Uncharacterized protein BH0493	(Halalkalibacterium halodurans C-125 ) [TaxId: 272558 ],	SCOPe (2.08)
G	d3hk7g_	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	Metallo-dependent hydrolases	Uronate isomerase-like	Uncharacterized protein BH0493	(Halalkalibacterium halodurans C-125 ) [TaxId: 272558 ],	SCOPe (2.08)
H	d3hk7h_	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	Metallo-dependent hydrolases	Uronate isomerase-like	Uncharacterized protein BH0493	(Halalkalibacterium halodurans C-125 ) [TaxId: 272558 ],	SCOPe (2.08)
I	d3hk7i_	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	Metallo-dependent hydrolases	Uronate isomerase-like	Uncharacterized protein BH0493	(Halalkalibacterium halodurans C-125 ) [TaxId: 272558 ],	SCOPe (2.08)
J	d3hk7j_	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	Metallo-dependent hydrolases	Uronate isomerase-like	Uncharacterized protein BH0493	(Halalkalibacterium halodurans C-125 ) [TaxId: 272558 ],	SCOPe (2.08)
K	d3hk7k_	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	Metallo-dependent hydrolases	Uronate isomerase-like	Uncharacterized protein BH0493	(Halalkalibacterium halodurans C-125 ) [TaxId: 272558 ],	SCOPe (2.08)
L	d3hk7l_	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	Metallo-dependent hydrolases	Uronate isomerase-like	Uncharacterized protein BH0493	(Halalkalibacterium halodurans C-125 ) [TaxId: 272558 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Metallo-dependent hydrolases	8035862	3000428	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Metallo-dependent hydrolases	8035862	3000428	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Metallo-dependent hydrolases	8035862	3000428	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Metallo-dependent hydrolases	8035862	3000428	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	Metallo-dependent hydrolases	8035862	3000428	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	Metallo-dependent hydrolases	8035862	3000428	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	Metallo-dependent hydrolases	8035862	3000428	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	Metallo-dependent hydrolases	8035862	3000428	SCOP2B (2022-06-29)
I	SCOP2B Superfamily	Metallo-dependent hydrolases	8035862	3000428	SCOP2B (2022-06-29)
J	SCOP2B Superfamily	Metallo-dependent hydrolases	8035862	3000428	SCOP2B (2022-06-29)
K	SCOP2B Superfamily	Metallo-dependent hydrolases	8035862	3000428	SCOP2B (2022-06-29)
L	SCOP2B Superfamily	Metallo-dependent hydrolases	8035862	3000428	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	F_UNCLASSIFIED	e3hk7A1	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: F_UNCLASSIFIED	ECOD (1.6)
B	F_UNCLASSIFIED	e3hk7B1	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: F_UNCLASSIFIED	ECOD (1.6)
C	F_UNCLASSIFIED	e3hk7C1	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: F_UNCLASSIFIED	ECOD (1.6)
D	F_UNCLASSIFIED	e3hk7D1	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: F_UNCLASSIFIED	ECOD (1.6)
E	F_UNCLASSIFIED	e3hk7E1	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: F_UNCLASSIFIED	ECOD (1.6)
F	F_UNCLASSIFIED	e3hk7F1	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: F_UNCLASSIFIED	ECOD (1.6)
G	F_UNCLASSIFIED	e3hk7G1	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: F_UNCLASSIFIED	ECOD (1.6)
H	F_UNCLASSIFIED	e3hk7H1	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: F_UNCLASSIFIED	ECOD (1.6)
I	F_UNCLASSIFIED	e3hk7I1	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: F_UNCLASSIFIED	ECOD (1.6)
J	F_UNCLASSIFIED	e3hk7J1	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: F_UNCLASSIFIED	ECOD (1.6)
K	F_UNCLASSIFIED	e3hk7K1	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: F_UNCLASSIFIED	ECOD (1.6)
L	F_UNCLASSIFIED	e3hk7L1	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: F_UNCLASSIFIED	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.10.2020.10	Mainly Alpha	Orthogonal Bundle	uronate isomerase, domain 2, chain A	uronate isomerase, domain 2, chain A	CATH (4.3.0)
B	1.10.2020.10	Mainly Alpha	Orthogonal Bundle	uronate isomerase, domain 2, chain A	uronate isomerase, domain 2, chain A	CATH (4.3.0)
C	1.10.2020.10	Mainly Alpha	Orthogonal Bundle	uronate isomerase, domain 2, chain A	uronate isomerase, domain 2, chain A	CATH (4.3.0)
D	1.10.2020.10	Mainly Alpha	Orthogonal Bundle	uronate isomerase, domain 2, chain A	uronate isomerase, domain 2, chain A	CATH (4.3.0)
E	1.10.2020.10	Mainly Alpha	Orthogonal Bundle	uronate isomerase, domain 2, chain A	uronate isomerase, domain 2, chain A	CATH (4.3.0)
F	1.10.2020.10	Mainly Alpha	Orthogonal Bundle	uronate isomerase, domain 2, chain A	uronate isomerase, domain 2, chain A	CATH (4.3.0)
G	1.10.2020.10	Mainly Alpha	Orthogonal Bundle	uronate isomerase, domain 2, chain A	uronate isomerase, domain 2, chain A	CATH (4.3.0)
H	1.10.2020.10	Mainly Alpha	Orthogonal Bundle	uronate isomerase, domain 2, chain A	uronate isomerase, domain 2, chain A	CATH (4.3.0)
I	1.10.2020.10	Mainly Alpha	Orthogonal Bundle	uronate isomerase, domain 2, chain A	uronate isomerase, domain 2, chain A	CATH (4.3.0)
J	1.10.2020.10	Mainly Alpha	Orthogonal Bundle	uronate isomerase, domain 2, chain A	uronate isomerase, domain 2, chain A	CATH (4.3.0)
K	1.10.2020.10	Mainly Alpha	Orthogonal Bundle	uronate isomerase, domain 2, chain A	uronate isomerase, domain 2, chain A	CATH (4.3.0)
L	1.10.2020.10	Mainly Alpha	Orthogonal Bundle	uronate isomerase, domain 2, chain A	uronate isomerase, domain 2, chain A	CATH (4.3.0)

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	Uronate isomerase	cation binding ion binding binding metal ion binding small molecule binding	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR032466	Metal-dependent hydrolase	Homologous Superfamily

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.