3HH1

The Structure of a Tetrapyrrole methylase family protein domain from Chlorobium tepidum TLS

External Resource: Annotation

Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
B	PF00590	e3hh1B1	A: a/b three-layered sandwiches	X: Tetrapyrrole methylase N-terminal domain (From Topology)	H: Tetrapyrrole methylase N-terminal domain (From Topology)	T: Tetrapyrrole methylase N-terminal domain	F: PF00590	ECOD (1.6)
A	PF00590	e3hh1A1	A: a/b three-layered sandwiches	X: Tetrapyrrole methylase N-terminal domain (From Topology)	H: Tetrapyrrole methylase N-terminal domain (From Topology)	T: Tetrapyrrole methylase N-terminal domain	F: PF00590	ECOD (1.6)
C	PF00590	e3hh1C1	A: a/b three-layered sandwiches	X: Tetrapyrrole methylase N-terminal domain (From Topology)	H: Tetrapyrrole methylase N-terminal domain (From Topology)	T: Tetrapyrrole methylase N-terminal domain	F: PF00590	ECOD (1.6)
D	PF00590	e3hh1D1	A: a/b three-layered sandwiches	X: Tetrapyrrole methylase N-terminal domain (From Topology)	H: Tetrapyrrole methylase N-terminal domain (From Topology)	T: Tetrapyrrole methylase N-terminal domain	F: PF00590	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
B	3.40.1010.10	Alpha Beta	3-Layer(aba) Sandwich	Cobalt-precorrin-4 Transmethylase	domain 1	CATH (4.3.0)
A	3.40.1010.10	Alpha Beta	3-Layer(aba) Sandwich	Cobalt-precorrin-4 Transmethylase	domain 1	CATH (4.3.0)
C	3.40.1010.10	Alpha Beta	3-Layer(aba) Sandwich	Cobalt-precorrin-4 Transmethylase	domain 1	CATH (4.3.0)
D	3.40.1010.10	Alpha Beta	3-Layer(aba) Sandwich	Cobalt-precorrin-4 Transmethylase	domain 1	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF00590	Tetrapyrrole (Corrin/Porphyrin) Methylases (TP_methylase)	Tetrapyrrole (Corrin/Porphyrin) Methylases	This family uses S-AdoMet in the methylation of diverse substrates. This family includes a related group of bacterial proteins of unknown function, including Swiss:P45528. This family includes the methylase Dipthine synthase.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	Tetrapyrrole methylase family protein	RNA methyltransferase activity O-methyltransferase activity rRNA methyltransferase activity catalytic activity, acting on RNA transferase activity, transferring one-carbon groups catalytic activity, acting on a nucleic acid transferase activity catalytic activity, acting on a rRNA S-adenosylmethionine-dependent methyltransferase activity rRNA (cytosine-2'-O-)-methyltransferase activity methyltransferase activity catalytic activity rRNA (cytosine) methyltransferase activity RNA 2'-O-methyltransferase activity	-	intracellular anatomical structure cytoplasm cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D	IPR035996	Tetrapyrrole methylase superfamily	Homologous Superfamily
A, B, C, D	IPR014777	Tetrapyrrole methylase, subdomain 1	Homologous Superfamily
A, B, C, D	IPR014776	Tetrapyrrole methylase, subdomain 2	Homologous Superfamily
A, B, C, D	IPR000878	Tetrapyrrole methylase	Domain
A, B, C, D	IPR008189	rRNA small subunit methyltransferase I	Family

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.