3GVD

Crystal Structure of Serine Acetyltransferase CysE from Yersinia pestis

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d3gvda_	All beta proteins	Single-stranded left-handed beta-helix	Trimeric LpxA-like enzymes	Serine acetyltransferase	automated matches	(Yersinia pestis ) [TaxId: 632 ],	SCOPe (2.08)
B	d3gvdb1	All beta proteins	Single-stranded left-handed beta-helix	Trimeric LpxA-like enzymes	Serine acetyltransferase	automated matches	(Yersinia pestis ) [TaxId: 632 ],	SCOPe (2.08)
B	d3gvdb2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Yersinia pestis ) [TaxId: 632 ],	SCOPe (2.08)
C	d3gvdc1	All beta proteins	Single-stranded left-handed beta-helix	Trimeric LpxA-like enzymes	Serine acetyltransferase	automated matches	(Yersinia pestis ) [TaxId: 632 ],	SCOPe (2.08)
C	d3gvdc2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Yersinia pestis ) [TaxId: 632 ],	SCOPe (2.08)
D	d3gvdd_	All beta proteins	Single-stranded left-handed beta-helix	Trimeric LpxA-like enzymes	Serine acetyltransferase	automated matches	(Yersinia pestis ) [TaxId: 632 ],	SCOPe (2.08)
E	d3gvde_	All beta proteins	Single-stranded left-handed beta-helix	Trimeric LpxA-like enzymes	Serine acetyltransferase	automated matches	(Yersinia pestis ) [TaxId: 632 ],	SCOPe (2.08)
F	d3gvdf_	All beta proteins	Single-stranded left-handed beta-helix	Trimeric LpxA-like enzymes	Serine acetyltransferase	automated matches	(Yersinia pestis ) [TaxId: 632 ],	SCOPe (2.08)
G	d3gvdg_	All beta proteins	Single-stranded left-handed beta-helix	Trimeric LpxA-like enzymes	Serine acetyltransferase	automated matches	(Yersinia pestis ) [TaxId: 632 ],	SCOPe (2.08)
H	d3gvdh1	All beta proteins	Single-stranded left-handed beta-helix	Trimeric LpxA-like enzymes	Serine acetyltransferase	automated matches	(Yersinia pestis ) [TaxId: 632 ],	SCOPe (2.08)
H	d3gvdh2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Yersinia pestis ) [TaxId: 632 ],	SCOPe (2.08)
I	d3gvdi1	All beta proteins	Single-stranded left-handed beta-helix	Trimeric LpxA-like enzymes	Serine acetyltransferase	automated matches	(Yersinia pestis ) [TaxId: 632 ],	SCOPe (2.08)
I	d3gvdi2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Yersinia pestis ) [TaxId: 632 ],	SCOPe (2.08)
J	d3gvdj_	All beta proteins	Single-stranded left-handed beta-helix	Trimeric LpxA-like enzymes	Serine acetyltransferase	automated matches	(Yersinia pestis ) [TaxId: 632 ],	SCOPe (2.08)
K	d3gvdk_	All beta proteins	Single-stranded left-handed beta-helix	Trimeric LpxA-like enzymes	Serine acetyltransferase	automated matches	(Yersinia pestis ) [TaxId: 632 ],	SCOPe (2.08)
L	d3gvdl_	All beta proteins	Single-stranded left-handed beta-helix	Trimeric LpxA-like enzymes	Serine acetyltransferase	automated matches	(Yersinia pestis ) [TaxId: 632 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Serine acetyltransferase	8101252	4001889	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Trimeric LpxA-like enzymes	8101253	3001804	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	Trimeric LpxA-like enzymes	8101253	3001804	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Trimeric LpxA-like enzymes	8101253	3001804	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Trimeric LpxA-like enzymes	8101253	3001804	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	Trimeric LpxA-like enzymes	8101253	3001804	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	Trimeric LpxA-like enzymes	8101253	3001804	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	Trimeric LpxA-like enzymes	8101253	3001804	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	Trimeric LpxA-like enzymes	8101253	3001804	SCOP2B (2022-06-29)
I	SCOP2B Superfamily	Trimeric LpxA-like enzymes	8101253	3001804	SCOP2B (2022-06-29)
J	SCOP2B Superfamily	Trimeric LpxA-like enzymes	8101253	3001804	SCOP2B (2022-06-29)
K	SCOP2B Superfamily	Trimeric LpxA-like enzymes	8101253	3001804	SCOP2B (2022-06-29)
L	SCOP2B Superfamily	Trimeric LpxA-like enzymes	8101253	3001804	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF00132	e3gvdA1	A: beta duplicates or obligate multimers	X: Single-stranded left-handed beta-helix	H: Trimeric LpxA-like enzymes (From Topology)	T: Trimeric LpxA-like enzymes	F: PF00132	ECOD (1.6)
A	PF06426	e3gvdA2	A: alpha arrays	X: Serine acetyltransferase N-terminal domain (From Topology)	H: Serine acetyltransferase N-terminal domain (From Topology)	T: Serine acetyltransferase N-terminal domain	F: PF06426	ECOD (1.6)
B	PF00132	e3gvdB1	A: beta duplicates or obligate multimers	X: Single-stranded left-handed beta-helix	H: Trimeric LpxA-like enzymes (From Topology)	T: Trimeric LpxA-like enzymes	F: PF00132	ECOD (1.6)
B	PF06426	e3gvdB2	A: alpha arrays	X: Serine acetyltransferase N-terminal domain (From Topology)	H: Serine acetyltransferase N-terminal domain (From Topology)	T: Serine acetyltransferase N-terminal domain	F: PF06426	ECOD (1.6)
C	PF00132	e3gvdC2	A: beta duplicates or obligate multimers	X: Single-stranded left-handed beta-helix	H: Trimeric LpxA-like enzymes (From Topology)	T: Trimeric LpxA-like enzymes	F: PF00132	ECOD (1.6)
C	PF06426	e3gvdC1	A: alpha arrays	X: Serine acetyltransferase N-terminal domain (From Topology)	H: Serine acetyltransferase N-terminal domain (From Topology)	T: Serine acetyltransferase N-terminal domain	F: PF06426	ECOD (1.6)
D	PF00132	e3gvdD1	A: beta duplicates or obligate multimers	X: Single-stranded left-handed beta-helix	H: Trimeric LpxA-like enzymes (From Topology)	T: Trimeric LpxA-like enzymes	F: PF00132	ECOD (1.6)
D	PF06426	e3gvdD2	A: alpha arrays	X: Serine acetyltransferase N-terminal domain (From Topology)	H: Serine acetyltransferase N-terminal domain (From Topology)	T: Serine acetyltransferase N-terminal domain	F: PF06426	ECOD (1.6)
E	PF00132	e3gvdE2	A: beta duplicates or obligate multimers	X: Single-stranded left-handed beta-helix	H: Trimeric LpxA-like enzymes (From Topology)	T: Trimeric LpxA-like enzymes	F: PF00132	ECOD (1.6)
E	PF06426	e3gvdE1	A: alpha arrays	X: Serine acetyltransferase N-terminal domain (From Topology)	H: Serine acetyltransferase N-terminal domain (From Topology)	T: Serine acetyltransferase N-terminal domain	F: PF06426	ECOD (1.6)
F	PF00132	e3gvdF1	A: beta duplicates or obligate multimers	X: Single-stranded left-handed beta-helix	H: Trimeric LpxA-like enzymes (From Topology)	T: Trimeric LpxA-like enzymes	F: PF00132	ECOD (1.6)
F	PF06426	e3gvdF2	A: alpha arrays	X: Serine acetyltransferase N-terminal domain (From Topology)	H: Serine acetyltransferase N-terminal domain (From Topology)	T: Serine acetyltransferase N-terminal domain	F: PF06426	ECOD (1.6)
G	PF00132	e3gvdG1	A: beta duplicates or obligate multimers	X: Single-stranded left-handed beta-helix	H: Trimeric LpxA-like enzymes (From Topology)	T: Trimeric LpxA-like enzymes	F: PF00132	ECOD (1.6)
G	PF06426	e3gvdG2	A: alpha arrays	X: Serine acetyltransferase N-terminal domain (From Topology)	H: Serine acetyltransferase N-terminal domain (From Topology)	T: Serine acetyltransferase N-terminal domain	F: PF06426	ECOD (1.6)
H	PF00132	e3gvdH2	A: beta duplicates or obligate multimers	X: Single-stranded left-handed beta-helix	H: Trimeric LpxA-like enzymes (From Topology)	T: Trimeric LpxA-like enzymes	F: PF00132	ECOD (1.6)
H	PF06426	e3gvdH1	A: alpha arrays	X: Serine acetyltransferase N-terminal domain (From Topology)	H: Serine acetyltransferase N-terminal domain (From Topology)	T: Serine acetyltransferase N-terminal domain	F: PF06426	ECOD (1.6)
I	PF00132	e3gvdI2	A: beta duplicates or obligate multimers	X: Single-stranded left-handed beta-helix	H: Trimeric LpxA-like enzymes (From Topology)	T: Trimeric LpxA-like enzymes	F: PF00132	ECOD (1.6)
I	PF06426	e3gvdI1	A: alpha arrays	X: Serine acetyltransferase N-terminal domain (From Topology)	H: Serine acetyltransferase N-terminal domain (From Topology)	T: Serine acetyltransferase N-terminal domain	F: PF06426	ECOD (1.6)
J	PF00132	e3gvdJ1	A: beta duplicates or obligate multimers	X: Single-stranded left-handed beta-helix	H: Trimeric LpxA-like enzymes (From Topology)	T: Trimeric LpxA-like enzymes	F: PF00132	ECOD (1.6)
J	PF06426	e3gvdJ2	A: alpha arrays	X: Serine acetyltransferase N-terminal domain (From Topology)	H: Serine acetyltransferase N-terminal domain (From Topology)	T: Serine acetyltransferase N-terminal domain	F: PF06426	ECOD (1.6)
K	PF00132	e3gvdK1	A: beta duplicates or obligate multimers	X: Single-stranded left-handed beta-helix	H: Trimeric LpxA-like enzymes (From Topology)	T: Trimeric LpxA-like enzymes	F: PF00132	ECOD (1.6)
K	PF06426	e3gvdK2	A: alpha arrays	X: Serine acetyltransferase N-terminal domain (From Topology)	H: Serine acetyltransferase N-terminal domain (From Topology)	T: Serine acetyltransferase N-terminal domain	F: PF06426	ECOD (1.6)
L	PF00132	e3gvdL2	A: beta duplicates or obligate multimers	X: Single-stranded left-handed beta-helix	H: Trimeric LpxA-like enzymes (From Topology)	T: Trimeric LpxA-like enzymes	F: PF00132	ECOD (1.6)
L	PF06426	e3gvdL1	A: alpha arrays	X: Serine acetyltransferase N-terminal domain (From Topology)	H: Serine acetyltransferase N-terminal domain (From Topology)	T: Serine acetyltransferase N-terminal domain	F: PF06426	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.10.3130.10	Mainly Alpha	Orthogonal Bundle	serine acetyltransferase, domain 1	serine acetyltransferase, domain 1	CATH (4.3.0)
A	2.160.10.10	Mainly Beta	3 Solenoid	UDP N-Acetylglucosamine Acyltransferase	domain 1	CATH (4.3.0)
B	1.10.3130.10	Mainly Alpha	Orthogonal Bundle	serine acetyltransferase, domain 1	serine acetyltransferase, domain 1	CATH (4.3.0)
B	2.160.10.10	Mainly Beta	3 Solenoid	UDP N-Acetylglucosamine Acyltransferase	domain 1	CATH (4.3.0)
C	1.10.3130.10	Mainly Alpha	Orthogonal Bundle	serine acetyltransferase, domain 1	serine acetyltransferase, domain 1	CATH (4.3.0)
C	2.160.10.10	Mainly Beta	3 Solenoid	UDP N-Acetylglucosamine Acyltransferase	domain 1	CATH (4.3.0)
D	1.10.3130.10	Mainly Alpha	Orthogonal Bundle	serine acetyltransferase, domain 1	serine acetyltransferase, domain 1	CATH (4.3.0)
D	2.160.10.10	Mainly Beta	3 Solenoid	UDP N-Acetylglucosamine Acyltransferase	domain 1	CATH (4.3.0)
E	1.10.3130.10	Mainly Alpha	Orthogonal Bundle	serine acetyltransferase, domain 1	serine acetyltransferase, domain 1	CATH (4.3.0)
E	2.160.10.10	Mainly Beta	3 Solenoid	UDP N-Acetylglucosamine Acyltransferase	domain 1	CATH (4.3.0)
F	1.10.3130.10	Mainly Alpha	Orthogonal Bundle	serine acetyltransferase, domain 1	serine acetyltransferase, domain 1	CATH (4.3.0)
F	2.160.10.10	Mainly Beta	3 Solenoid	UDP N-Acetylglucosamine Acyltransferase	domain 1	CATH (4.3.0)
G	1.10.3130.10	Mainly Alpha	Orthogonal Bundle	serine acetyltransferase, domain 1	serine acetyltransferase, domain 1	CATH (4.3.0)
G	2.160.10.10	Mainly Beta	3 Solenoid	UDP N-Acetylglucosamine Acyltransferase	domain 1	CATH (4.3.0)
H	1.10.3130.10	Mainly Alpha	Orthogonal Bundle	serine acetyltransferase, domain 1	serine acetyltransferase, domain 1	CATH (4.3.0)
H	2.160.10.10	Mainly Beta	3 Solenoid	UDP N-Acetylglucosamine Acyltransferase	domain 1	CATH (4.3.0)
I	1.10.3130.10	Mainly Alpha	Orthogonal Bundle	serine acetyltransferase, domain 1	serine acetyltransferase, domain 1	CATH (4.3.0)
I	2.160.10.10	Mainly Beta	3 Solenoid	UDP N-Acetylglucosamine Acyltransferase	domain 1	CATH (4.3.0)
J	1.10.3130.10	Mainly Alpha	Orthogonal Bundle	serine acetyltransferase, domain 1	serine acetyltransferase, domain 1	CATH (4.3.0)
J	2.160.10.10	Mainly Beta	3 Solenoid	UDP N-Acetylglucosamine Acyltransferase	domain 1	CATH (4.3.0)
K	1.10.3130.10	Mainly Alpha	Orthogonal Bundle	serine acetyltransferase, domain 1	serine acetyltransferase, domain 1	CATH (4.3.0)
K	2.160.10.10	Mainly Beta	3 Solenoid	UDP N-Acetylglucosamine Acyltransferase	domain 1	CATH (4.3.0)
L	1.10.3130.10	Mainly Alpha	Orthogonal Bundle	serine acetyltransferase, domain 1	serine acetyltransferase, domain 1	CATH (4.3.0)
L	2.160.10.10	Mainly Beta	3 Solenoid	UDP N-Acetylglucosamine Acyltransferase	domain 1	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	PF00132	Bacterial transferase hexapeptide (six repeats) (Hexapep)	Bacterial transferase hexapeptide (six repeats)	-	Repeat
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	PF06426	Serine acetyltransferase, N-terminal (SATase_N)	Serine acetyltransferase, N-terminal	The N-terminal domain of serine acetyltransferase has a sequence that is conserved in plants [2] and bacteria [1].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	Serine acetyltransferase	acetyltransferase activity serine O-acyltransferase activity O-acyltransferase activity serine O-acetyltransferase activity acyltransferase activity acyltransferase activity, transferring groups other than amino-acyl groups transferase activity O-acetyltransferase activity catalytic activity	serine family amino acid metabolic process oxoacid metabolic process cellular biosynthetic process sulfur amino acid metabolic process organonitrogen compound biosynthetic process amino acid metabolic process organic acid biosynthetic process organic acid metabolic process alpha-amino acid metabolic process carboxylic acid biosynthetic process cysteine biosynthetic process organic substance metabolic process organic substance biosynthetic process small molecule metabolic process serine family amino acid metabolic process oxoacid metabolic process cellular biosynthetic process sulfur amino acid metabolic process organonitrogen compound biosynthetic process amino acid metabolic process organic acid biosynthetic process organic acid metabolic process alpha-amino acid metabolic process carboxylic acid biosynthetic process cysteine biosynthetic process organic substance metabolic process organic substance biosynthetic process small molecule metabolic process sulfur compound metabolic process organonitrogen compound metabolic process cysteine biosynthetic process from serine small molecule biosynthetic process cellular metabolic process carboxylic acid metabolic process primary metabolic process L-amino acid biosynthetic process L-serine metabolic process L-amino acid metabolic process cysteine metabolic process proteinogenic amino acid metabolic process amino acid biosynthetic process sulfur compound biosynthetic process biosynthetic process proteinogenic amino acid biosynthetic process metabolic process cellular process serine family amino acid biosynthetic process sulfur amino acid biosynthetic process alpha-amino acid biosynthetic process	intracellular anatomical structure cytoplasm cellular anatomical entity cytosol

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR045304	Serine acetyltransferase, LbH domain	Domain
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR042122	Serine acetyltransferase, N-terminal domain superfamily	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR011004	Trimeric LpxA-like superfamily	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR010493	Serine acetyltransferase, N-terminal	Domain
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR005881	Serine O-acetyltransferase	Family
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR018357	Hexapeptide transferase, conserved site	Conserved Site
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR001451	Hexapeptide repeat	Repeat