3GQ2

Crystal Structure of the Dimer of the p115 Tether Globular Head Domain

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	ARM repeat-like	8102725	3000116	SCOP2B (2022-06-29)
B	SCOP2 Family	p115 tether globular head domain	8046580	4005169	SCOP2 (2022-06-29)
B	SCOP2 Superfamily	ARM repeat-like	8102725	3000116	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF04869,PF18770	e3gq2A1	A: alpha superhelices	X: Repetitive alpha hairpins	H: ARM repeat (From Topology)	T: ARM repeat	F: PF04869,PF18770	ECOD (1.6)
B	PF04869,PF18770	e3gq2B1	A: alpha superhelices	X: Repetitive alpha hairpins	H: ARM repeat (From Topology)	T: ARM repeat	F: PF04869,PF18770	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.25.10.10	Mainly Alpha	Alpha Horseshoe	Leucine-rich Repeat Variant	Leucine-rich Repeat Variant	CATH (4.3.0)
B	1.25.10.10	Mainly Alpha	Alpha Horseshoe	Leucine-rich Repeat Variant	Leucine-rich Repeat Variant	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF18770	Armadillo tether-repeat of vescicular transport factor (Arm_vescicular)	Armadillo tether-repeat of vescicular transport factor	-	Repeat
A, B	PF04869	Uso1 / p115 like vesicle tethering protein, head region (Uso1_p115_head)	Uso1 / p115 like vesicle tethering protein, head region	-	Repeat

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	General vesicular transport factor p115	identical protein binding protein binding binding	membrane organization cellular component organization membrane fusion cellular process cellular component organization or biogenesis protein localization cellular localization establishment of protein localization nitrogen compound transport transport organic substance transport intracellular transport establishment of localization localization membrane organization cellular component organization membrane fusion cellular process cellular component organization or biogenesis protein localization cellular localization establishment of protein localization nitrogen compound transport transport organic substance transport intracellular transport establishment of localization localization protein transport establishment of localization in cell cellular macromolecule localization macromolecule localization intracellular protein transport multicellular organismal process transcytosis vesicle-mediated transport membrane docking organelle localization by membrane tethering Golgi vesicle docking organelle localization vesicle docking Golgi vesicle transport cellular component biogenesis cellular component assembly protein-containing complex organization protein complex oligomerization protein-containing complex assembly protein homooligomerization endoplasmic reticulum to Golgi vesicle-mediated transport organelle membrane fusion vesicle organization organelle fusion organelle organization vesicle fusion with Golgi apparatus vesicle fusion Golgi organization endomembrane system organization inter-Golgi cisterna vesicle-mediated transport intra-Golgi vesicle-mediated transport	membrane-bounded organelle intracellular anatomical structure Golgi apparatus subcompartment Golgi apparatus organelle subcompartment cellular anatomical entity intracellular membrane-bounded organelle endomembrane system intracellular organelle organelle Golgi stack cytoplasm Golgi membrane cytoplasmic side of membrane membrane-bounded organelle intracellular anatomical structure Golgi apparatus subcompartment Golgi apparatus organelle subcompartment cellular anatomical entity intracellular membrane-bounded organelle endomembrane system intracellular organelle organelle Golgi stack cytoplasm Golgi membrane cytoplasmic side of membrane membrane cytoplasmic side of Golgi membrane side of membrane bounding membrane of organelle organelle membrane cytosol perinuclear region of cytoplasm transport vesicle intracellular vesicle transport vesicle membrane cytoplasmic vesicle membrane coated vesicle membrane COPII-coated ER to Golgi transport vesicle vesicle membrane cytoplasmic vesicle ER to Golgi transport vesicle membrane coated vesicle vesicle endoplasmic reticulum

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR016024	Armadillo-type fold	Homologous Superfamily
A, B	IPR006953	Vesicle tethering protein Uso1/P115-like, head domain	Domain
A, B	IPR041209	Vesicle tethering protein p115, armadillo tether-repeat	Repeat
A, B	IPR000225	Armadillo	Repeat
A, B	IPR011989	Armadillo-like helical	Homologous Superfamily
A, B	IPR006955	Uso1/p115-like vesicle tethering protein, C-terminal	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.