3FZQ

Crystal structure of putative haloacid dehalogenase-like hydrolase (YP_001086940.1) from Clostridium difficile 630 at 2.10 A resolution

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d3fzqa_	Alpha and beta proteins (a/b)	HAD-like	HAD-like	automated matches	automated matches	(Clostridioides difficile 630 ) [TaxId: 272563 ],	SCOPe (2.08)
B	d3fzqb_	Alpha and beta proteins (a/b)	HAD-like	HAD-like	automated matches	automated matches	(Clostridioides difficile 630 ) [TaxId: 272563 ],	SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	F_UNCLASSIFIED	e3fzqA2	A: a+b two layers	X: Cof C2 cap domain (From Topology)	H: Cof C2 cap domain (From Topology)	T: Cof C2 cap domain	F: F_UNCLASSIFIED	ECOD (1.6)
A	PF08282	e3fzqA1	A: a/b three-layered sandwiches	X: HAD domain-like	H: HAD domain-related	T: HAD-like	F: PF08282	ECOD (1.6)
B	F_UNCLASSIFIED	e3fzqB2	A: a+b two layers	X: Cof C2 cap domain (From Topology)	H: Cof C2 cap domain (From Topology)	T: Cof C2 cap domain	F: F_UNCLASSIFIED	ECOD (1.6)
B	PF08282	e3fzqB1	A: a/b three-layered sandwiches	X: HAD domain-like	H: HAD domain-related	T: HAD-like	F: PF08282	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.50.1000	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	HAD superfamily/HAD-like	CATH (4.3.0)
A	3.30.1240.10	Alpha Beta	2-Layer Sandwich	Hypothetical Protein, Haloacid Dehalogenase-like Hydrolase	Chain: A	CATH (4.3.0)
B	3.40.50.1000	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	HAD superfamily/HAD-like	CATH (4.3.0)
B	3.30.1240.10	Alpha Beta	2-Layer Sandwich	Hypothetical Protein, Haloacid Dehalogenase-like Hydrolase	Chain: A	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF08282	haloacid dehalogenase-like hydrolase (Hydrolase_3)	haloacid dehalogenase-like hydrolase	This family contains haloacid dehalogenase-like hydrolase enzymes.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Putative hydrolase	phosphoric ester hydrolase activity hydrolase activity, acting on ester bonds phosphatase activity hydrolase activity catalytic activity	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR000150	Cof family	Family
A, B	IPR036412	HAD-like superfamily	Homologous Superfamily
A, B	IPR023214	HAD superfamily	Homologous Superfamily
A, B	IPR006379	HAD-superfamily hydrolase, subfamily IIB	Family

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.