3FV9

Crystal structure of putative mandelate racemase/muconatelactonizing enzyme from ROSEOVARIUS NUBINHIBENS ISM complexed with magnesium

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A [auth G]	d3fv9g2	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	Enolase C-terminal domain-like	automated matches	automated matches	(Roseovarius nubinhibens ISM ) [TaxId: 89187 ],	SCOPe (2.08)
A [auth G]	d3fv9g1	Alpha and beta proteins (a+b)	Enolase N-terminal domain-like	Enolase N-terminal domain-like	automated matches	automated matches	(Roseovarius nubinhibens ISM ) [TaxId: 89187 ],	SCOPe (2.08)
A [auth G]	d3fv9g3	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Roseovarius nubinhibens ISM ) [TaxId: 89187 ],	SCOPe (2.08)
B [auth A]	d3fv9a2	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	Enolase C-terminal domain-like	automated matches	automated matches	(Roseovarius nubinhibens ISM ) [TaxId: 89187 ],	SCOPe (2.08)
B [auth A]	d3fv9a1	Alpha and beta proteins (a+b)	Enolase N-terminal domain-like	Enolase N-terminal domain-like	automated matches	automated matches	(Roseovarius nubinhibens ISM ) [TaxId: 89187 ],	SCOPe (2.08)
B [auth A]	d3fv9a3	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Roseovarius nubinhibens ISM ) [TaxId: 89187 ],	SCOPe (2.08)
C [auth D]	d3fv9d2	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	Enolase C-terminal domain-like	automated matches	automated matches	(Roseovarius nubinhibens ISM ) [TaxId: 89187 ],	SCOPe (2.08)
C [auth D]	d3fv9d1	Alpha and beta proteins (a+b)	Enolase N-terminal domain-like	Enolase N-terminal domain-like	automated matches	automated matches	(Roseovarius nubinhibens ISM ) [TaxId: 89187 ],	SCOPe (2.08)
C [auth D]	d3fv9d3	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Roseovarius nubinhibens ISM ) [TaxId: 89187 ],	SCOPe (2.08)
D [auth E]	d3fv9e2	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	Enolase C-terminal domain-like	automated matches	automated matches	(Roseovarius nubinhibens ISM ) [TaxId: 89187 ],	SCOPe (2.08)
D [auth E]	d3fv9e1	Alpha and beta proteins (a+b)	Enolase N-terminal domain-like	Enolase N-terminal domain-like	automated matches	automated matches	(Roseovarius nubinhibens ISM ) [TaxId: 89187 ],	SCOPe (2.08)
D [auth E]	d3fv9e3	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Roseovarius nubinhibens ISM ) [TaxId: 89187 ],	SCOPe (2.08)
E [auth F]	d3fv9f2	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	Enolase C-terminal domain-like	automated matches	automated matches	(Roseovarius nubinhibens ISM ) [TaxId: 89187 ],	SCOPe (2.08)
E [auth F]	d3fv9f1	Alpha and beta proteins (a+b)	Enolase N-terminal domain-like	Enolase N-terminal domain-like	automated matches	automated matches	(Roseovarius nubinhibens ISM ) [TaxId: 89187 ],	SCOPe (2.08)
E [auth F]	d3fv9f3	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Roseovarius nubinhibens ISM ) [TaxId: 89187 ],	SCOPe (2.08)
F [auth B]	d3fv9b2	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	Enolase C-terminal domain-like	automated matches	automated matches	(Roseovarius nubinhibens ISM ) [TaxId: 89187 ],	SCOPe (2.08)
F [auth B]	d3fv9b1	Alpha and beta proteins (a+b)	Enolase N-terminal domain-like	Enolase N-terminal domain-like	automated matches	automated matches	(Roseovarius nubinhibens ISM ) [TaxId: 89187 ],	SCOPe (2.08)
F [auth B]	d3fv9b3	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Roseovarius nubinhibens ISM ) [TaxId: 89187 ],	SCOPe (2.08)
G [auth H]	d3fv9h2	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	Enolase C-terminal domain-like	automated matches	automated matches	(Roseovarius nubinhibens ISM ) [TaxId: 89187 ],	SCOPe (2.08)
G [auth H]	d3fv9h1	Alpha and beta proteins (a+b)	Enolase N-terminal domain-like	Enolase N-terminal domain-like	automated matches	automated matches	(Roseovarius nubinhibens ISM ) [TaxId: 89187 ],	SCOPe (2.08)
G [auth H]	d3fv9h3	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Roseovarius nubinhibens ISM ) [TaxId: 89187 ],	SCOPe (2.08)
H [auth C]	d3fv9c2	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	Enolase C-terminal domain-like	automated matches	automated matches	(Roseovarius nubinhibens ISM ) [TaxId: 89187 ],	SCOPe (2.08)
H [auth C]	d3fv9c1	Alpha and beta proteins (a+b)	Enolase N-terminal domain-like	Enolase N-terminal domain-like	automated matches	automated matches	(Roseovarius nubinhibens ISM ) [TaxId: 89187 ],	SCOPe (2.08)
H [auth C]	d3fv9c3	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Roseovarius nubinhibens ISM ) [TaxId: 89187 ],	SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A [auth G]	MR_MLE_N	e3fv9G1	A: a+b two layers	X: Enolase-N/ribosomal protein	H: Enolase N-terminal domain-like (From Topology)	T: Enolase N-terminal domain-like	F: MR_MLE_N	ECOD (1.6)
A [auth G]	MR_MLE_C_1	e3fv9G2	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: MR_MLE_C_1	ECOD (1.6)
B [auth A]	MR_MLE_N	e3fv9A1	A: a+b two layers	X: Enolase-N/ribosomal protein	H: Enolase N-terminal domain-like (From Topology)	T: Enolase N-terminal domain-like	F: MR_MLE_N	ECOD (1.6)
B [auth A]	MR_MLE_C_1	e3fv9A2	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: MR_MLE_C_1	ECOD (1.6)
C [auth D]	MR_MLE_N	e3fv9D1	A: a+b two layers	X: Enolase-N/ribosomal protein	H: Enolase N-terminal domain-like (From Topology)	T: Enolase N-terminal domain-like	F: MR_MLE_N	ECOD (1.6)
C [auth D]	MR_MLE_C_1	e3fv9D2	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: MR_MLE_C_1	ECOD (1.6)
D [auth E]	MR_MLE_N	e3fv9E1	A: a+b two layers	X: Enolase-N/ribosomal protein	H: Enolase N-terminal domain-like (From Topology)	T: Enolase N-terminal domain-like	F: MR_MLE_N	ECOD (1.6)
D [auth E]	MR_MLE_C_1	e3fv9E2	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: MR_MLE_C_1	ECOD (1.6)
E [auth F]	MR_MLE_N	e3fv9F1	A: a+b two layers	X: Enolase-N/ribosomal protein	H: Enolase N-terminal domain-like (From Topology)	T: Enolase N-terminal domain-like	F: MR_MLE_N	ECOD (1.6)
E [auth F]	MR_MLE_C_1	e3fv9F2	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: MR_MLE_C_1	ECOD (1.6)
F [auth B]	MR_MLE_N	e3fv9B1	A: a+b two layers	X: Enolase-N/ribosomal protein	H: Enolase N-terminal domain-like (From Topology)	T: Enolase N-terminal domain-like	F: MR_MLE_N	ECOD (1.6)
F [auth B]	MR_MLE_C_1	e3fv9B2	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: MR_MLE_C_1	ECOD (1.6)
G [auth H]	MR_MLE_N	e3fv9H1	A: a+b two layers	X: Enolase-N/ribosomal protein	H: Enolase N-terminal domain-like (From Topology)	T: Enolase N-terminal domain-like	F: MR_MLE_N	ECOD (1.6)
G [auth H]	MR_MLE_C_1	e3fv9H2	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: MR_MLE_C_1	ECOD (1.6)
H [auth C]	MR_MLE_N	e3fv9C1	A: a+b two layers	X: Enolase-N/ribosomal protein	H: Enolase N-terminal domain-like (From Topology)	T: Enolase N-terminal domain-like	F: MR_MLE_N	ECOD (1.6)
H [auth C]	MR_MLE_C_1	e3fv9C2	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: MR_MLE_C_1	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A [auth G]	3.30.390.10	Alpha Beta	2-Layer Sandwich	Enolase-like	domain 1	CATH (4.3.0)
A [auth G]	3.20.20.120	Alpha Beta	Alpha-Beta Barrel	TIM Barrel	Enolase-like C-terminal domain	CATH (4.3.0)
B [auth A]	3.30.390.10	Alpha Beta	2-Layer Sandwich	Enolase-like	domain 1	CATH (4.3.0)
B [auth A]	3.20.20.120	Alpha Beta	Alpha-Beta Barrel	TIM Barrel	Enolase-like C-terminal domain	CATH (4.3.0)
C [auth D]	3.30.390.10	Alpha Beta	2-Layer Sandwich	Enolase-like	domain 1	CATH (4.3.0)
C [auth D]	3.20.20.120	Alpha Beta	Alpha-Beta Barrel	TIM Barrel	Enolase-like C-terminal domain	CATH (4.3.0)
D [auth E]	3.30.390.10	Alpha Beta	2-Layer Sandwich	Enolase-like	domain 1	CATH (4.3.0)
D [auth E]	3.20.20.120	Alpha Beta	Alpha-Beta Barrel	TIM Barrel	Enolase-like C-terminal domain	CATH (4.3.0)
E [auth F]	3.30.390.10	Alpha Beta	2-Layer Sandwich	Enolase-like	domain 1	CATH (4.3.0)
E [auth F]	3.20.20.120	Alpha Beta	Alpha-Beta Barrel	TIM Barrel	Enolase-like C-terminal domain	CATH (4.3.0)
F [auth B]	3.30.390.10	Alpha Beta	2-Layer Sandwich	Enolase-like	domain 1	CATH (4.3.0)
F [auth B]	3.20.20.120	Alpha Beta	Alpha-Beta Barrel	TIM Barrel	Enolase-like C-terminal domain	CATH (4.3.0)
G [auth H]	3.30.390.10	Alpha Beta	2-Layer Sandwich	Enolase-like	domain 1	CATH (4.3.0)
G [auth H]	3.20.20.120	Alpha Beta	Alpha-Beta Barrel	TIM Barrel	Enolase-like C-terminal domain	CATH (4.3.0)
H [auth C]	3.30.390.10	Alpha Beta	2-Layer Sandwich	Enolase-like	domain 1	CATH (4.3.0)
H [auth C]	3.20.20.120	Alpha Beta	Alpha-Beta Barrel	TIM Barrel	Enolase-like C-terminal domain	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A [auth G], B [auth A], C [auth D], D [auth E], E [auth F], A [auth G], B [auth A], C [auth D], D [auth E], E [auth F], F [auth B], G [auth H], H [auth C]	PF02746	Mandelate racemase / muconate lactonizing enzyme, N-terminal domain (MR_MLE_N)	Mandelate racemase / muconate lactonizing enzyme, N-terminal domain	SCOP reports fold similarity with enolase N-terminal domain.	Domain
A [auth G], B [auth A], C [auth D], D [auth E], E [auth F], A [auth G], B [auth A], C [auth D], D [auth E], E [auth F], F [auth B], G [auth H], H [auth C]	PF13378	Enolase C-terminal domain-like (MR_MLE_C)	Enolase C-terminal domain-like	This domain appears at the C-terminus of many of the proteins that carry the MR_MLE_N Pfam:PF02746 domain. EC:4.2.1.40.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth G], B [auth A], C [auth D], D [auth E], E [auth F], A [auth G], B [auth A], C [auth D], D [auth E], E [auth F], F [auth B], G [auth H], H [auth C]	Mandelate racemase/muconate lactonizing enzyme	catalytic activity cation binding ion binding binding metal ion binding small molecule binding	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A [auth G], B [auth A], C [auth D], D [auth E], E [auth F], A [auth G], B [auth A], C [auth D], D [auth E], E [auth F], F [auth B], G [auth H], H [auth C]	IPR034593	D-galactonate dehydratase DgoD-like	Family
A [auth G], B [auth A], C [auth D], D [auth E], E [auth F], A [auth G], B [auth A], C [auth D], D [auth E], E [auth F], F [auth B], G [auth H], H [auth C]	IPR029065	Enolase C-terminal domain-like	Domain
A [auth G], B [auth A], C [auth D], D [auth E], E [auth F], A [auth G], B [auth A], C [auth D], D [auth E], E [auth F], F [auth B], G [auth H], H [auth C]	IPR013341	Mandelate racemase/muconate lactonizing enzyme, N-terminal domain	Domain
A [auth G], B [auth A], C [auth D], D [auth E], E [auth F], A [auth G], B [auth A], C [auth D], D [auth E], E [auth F], F [auth B], G [auth H], H [auth C]	IPR029017	Enolase-like, N-terminal	Homologous Superfamily
A [auth G], B [auth A], C [auth D], D [auth E], E [auth F], A [auth G], B [auth A], C [auth D], D [auth E], E [auth F], F [auth B], G [auth H], H [auth C]	IPR036849	Enolase-like, C-terminal domain superfamily	Homologous Superfamily