3FQC
Staphylococcus aureus dihydrofolate reductase complexed with NADPH and 2,4-diamino-5-[3-(3,4,5-trimethoxyphenyl)pent-1-ynyl]-6-methylpyrimidine (UCP115A)
External Resource: Annotation
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
| Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
|---|---|---|---|---|---|---|---|---|
| A | d3fqca_ | Alpha and beta proteins (a/b) | Dihydrofolate reductase-like | Dihydrofolate reductase-like | automated matches | automated matches | (Staphylococcus aureus RF122 ) [TaxId: 273036 ], | SCOPe (2.08) |
| B | d3fqcb_ | Alpha and beta proteins (a/b) | Dihydrofolate reductase-like | Dihydrofolate reductase-like | automated matches | automated matches | (Staphylococcus aureus RF122 ) [TaxId: 273036 ], | SCOPe (2.08) |
Domain Annotation: ECOD Classification ECOD Database Homepage
| Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
|---|---|---|---|---|---|---|---|---|
| A | PF00186 | e3fqcA1 | A: a/b three-layered sandwiches | X: Dihydrofolate reductases (From Topology) | H: Dihydrofolate reductases (From Topology) | T: Dihydrofolate reductases | F: PF00186 | ECOD (1.6) |
| B | PF00186 | e3fqcB1 | A: a/b three-layered sandwiches | X: Dihydrofolate reductases (From Topology) | H: Dihydrofolate reductases (From Topology) | T: Dihydrofolate reductases | F: PF00186 | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
| Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
|---|---|---|---|---|---|---|
| A | 3.40.430.10 | Alpha Beta | 3-Layer(aba) Sandwich | Dihydrofolate Reductase, subunit A | Dihydrofolate Reductase, subunit A | CATH (4.3.0) |
| B | 3.40.430.10 | Alpha Beta | 3-Layer(aba) Sandwich | Dihydrofolate Reductase, subunit A | Dihydrofolate Reductase, subunit A | CATH (4.3.0) |
