3FP9

Crystal structure of Intern Domain of proteasome-associated ATPase, Mycobacterium tuberculosis

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
B	SCOP2B Superfamily	HypC/PAN OB-fold domain-like	8091037	3000354	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	HypC/PAN OB-fold domain-like	8091036	3000354	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	HypC/PAN OB-fold domain-like	8091037	3000354	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	HypC/PAN OB-fold domain-like	8091037	3000354	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	HypC/PAN OB-fold domain-like	8091036	3000354	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	HypC/PAN OB-fold domain-like	8091036	3000354	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	HypC/PAN OB-fold domain-like	8091037	3000354	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	HypC/PAN OB-fold domain-like	8091036	3000354	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	HypC/PAN OB-fold domain-like	8091037	3000354	SCOP2B (2022-06-29)
F	SCOP2 Family	Arc OB C-terminal domain-like	8045602	4004561	SCOP2 (2022-06-29)
F	SCOP2 Family	Arc OB N-terminal domain-like	8091035	4007720	SCOP2 (2022-06-29)
F	SCOP2 Superfamily	HypC/PAN OB-fold domain-like	8091036	3000354	SCOP2 (2022-06-29)
F	SCOP2 Superfamily	HypC/PAN OB-fold domain-like	8091037	3000354	SCOP2 (2022-06-29)
G	SCOP2B Superfamily	HypC/PAN OB-fold domain-like	8091036	3000354	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	HypC/PAN OB-fold domain-like	8091037	3000354	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	HypC/PAN OB-fold domain-like	8091036	3000354	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	HypC/PAN OB-fold domain-like	8091037	3000354	SCOP2B (2022-06-29)
I	SCOP2B Superfamily	HypC/PAN OB-fold domain-like	8091036	3000354	SCOP2B (2022-06-29)
I	SCOP2B Superfamily	HypC/PAN OB-fold domain-like	8091037	3000354	SCOP2B (2022-06-29)
J	SCOP2B Superfamily	HypC/PAN OB-fold domain-like	8091036	3000354	SCOP2B (2022-06-29)
J	SCOP2B Superfamily	HypC/PAN OB-fold domain-like	8091037	3000354	SCOP2B (2022-06-29)
K	SCOP2B Superfamily	HypC/PAN OB-fold domain-like	8091036	3000354	SCOP2B (2022-06-29)
K	SCOP2B Superfamily	HypC/PAN OB-fold domain-like	8091037	3000354	SCOP2B (2022-06-29)
L	SCOP2B Superfamily	HypC/PAN OB-fold domain-like	8091036	3000354	SCOP2B (2022-06-29)
L	SCOP2B Superfamily	HypC/PAN OB-fold domain-like	8091037	3000354	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
B	PF16450	e3fp9B2	A: beta barrels	X: OB-fold	H: Nucleic acid-binding proteins (From Topology)	T: Nucleic acid-binding proteins	F: PF16450	ECOD (1.6)
B	PF17758	e3fp9B1	A: beta barrels	X: OB-fold	H: Nucleic acid-binding proteins (From Topology)	T: Nucleic acid-binding proteins	F: PF17758	ECOD (1.6)
E	PF16450	e3fp9E4	A: beta barrels	X: OB-fold	H: Nucleic acid-binding proteins (From Topology)	T: Nucleic acid-binding proteins	F: PF16450	ECOD (1.6)
E	PF17758	e3fp9E3	A: beta barrels	X: OB-fold	H: Nucleic acid-binding proteins (From Topology)	T: Nucleic acid-binding proteins	F: PF17758	ECOD (1.6)
A	PF16450	e3fp9A2	A: beta barrels	X: OB-fold	H: Nucleic acid-binding proteins (From Topology)	T: Nucleic acid-binding proteins	F: PF16450	ECOD (1.6)
A	PF17758	e3fp9A1	A: beta barrels	X: OB-fold	H: Nucleic acid-binding proteins (From Topology)	T: Nucleic acid-binding proteins	F: PF17758	ECOD (1.6)
C	PF16450	e3fp9C2	A: beta barrels	X: OB-fold	H: Nucleic acid-binding proteins (From Topology)	T: Nucleic acid-binding proteins	F: PF16450	ECOD (1.6)
C	PF17758	e3fp9C1	A: beta barrels	X: OB-fold	H: Nucleic acid-binding proteins (From Topology)	T: Nucleic acid-binding proteins	F: PF17758	ECOD (1.6)
D	PF16450	e3fp9D2	A: beta barrels	X: OB-fold	H: Nucleic acid-binding proteins (From Topology)	T: Nucleic acid-binding proteins	F: PF16450	ECOD (1.6)
D	PF17758	e3fp9D1	A: beta barrels	X: OB-fold	H: Nucleic acid-binding proteins (From Topology)	T: Nucleic acid-binding proteins	F: PF17758	ECOD (1.6)
F	PF16450	e3fp9F3	A: beta barrels	X: OB-fold	H: Nucleic acid-binding proteins (From Topology)	T: Nucleic acid-binding proteins	F: PF16450	ECOD (1.6)
F	PF17758	e3fp9F4	A: beta barrels	X: OB-fold	H: Nucleic acid-binding proteins (From Topology)	T: Nucleic acid-binding proteins	F: PF17758	ECOD (1.6)
G	PF16450	e3fp9G2	A: beta barrels	X: OB-fold	H: Nucleic acid-binding proteins (From Topology)	T: Nucleic acid-binding proteins	F: PF16450	ECOD (1.6)
G	PF17758	e3fp9G1	A: beta barrels	X: OB-fold	H: Nucleic acid-binding proteins (From Topology)	T: Nucleic acid-binding proteins	F: PF17758	ECOD (1.6)
H	PF16450	e3fp9H2	A: beta barrels	X: OB-fold	H: Nucleic acid-binding proteins (From Topology)	T: Nucleic acid-binding proteins	F: PF16450	ECOD (1.6)
H	PF17758	e3fp9H1	A: beta barrels	X: OB-fold	H: Nucleic acid-binding proteins (From Topology)	T: Nucleic acid-binding proteins	F: PF17758	ECOD (1.6)
I	PF16450	e3fp9I2	A: beta barrels	X: OB-fold	H: Nucleic acid-binding proteins (From Topology)	T: Nucleic acid-binding proteins	F: PF16450	ECOD (1.6)
I	PF17758	e3fp9I1	A: beta barrels	X: OB-fold	H: Nucleic acid-binding proteins (From Topology)	T: Nucleic acid-binding proteins	F: PF17758	ECOD (1.6)
J	PF16450	e3fp9J2	A: beta barrels	X: OB-fold	H: Nucleic acid-binding proteins (From Topology)	T: Nucleic acid-binding proteins	F: PF16450	ECOD (1.6)
J	PF17758	e3fp9J1	A: beta barrels	X: OB-fold	H: Nucleic acid-binding proteins (From Topology)	T: Nucleic acid-binding proteins	F: PF17758	ECOD (1.6)
K	PF16450	e3fp9K3	A: beta barrels	X: OB-fold	H: Nucleic acid-binding proteins (From Topology)	T: Nucleic acid-binding proteins	F: PF16450	ECOD (1.6)
K	PF17758	e3fp9K4	A: beta barrels	X: OB-fold	H: Nucleic acid-binding proteins (From Topology)	T: Nucleic acid-binding proteins	F: PF17758	ECOD (1.6)
L	PF16450	e3fp9L3	A: beta barrels	X: OB-fold	H: Nucleic acid-binding proteins (From Topology)	T: Nucleic acid-binding proteins	F: PF16450	ECOD (1.6)
L	PF17758	e3fp9L4	A: beta barrels	X: OB-fold	H: Nucleic acid-binding proteins (From Topology)	T: Nucleic acid-binding proteins	F: PF17758	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
B	2.40.50.140	Mainly Beta	Beta Barrel	OB fold (Dihydrolipoamide Acetyltransferase, E2P)	Nucleic acid-binding proteins	CATH (4.3.0)
E	2.40.50.140	Mainly Beta	Beta Barrel	OB fold (Dihydrolipoamide Acetyltransferase, E2P)	Nucleic acid-binding proteins	CATH (4.3.0)
A	2.40.50.140	Mainly Beta	Beta Barrel	OB fold (Dihydrolipoamide Acetyltransferase, E2P)	Nucleic acid-binding proteins	CATH (4.3.0)
C	2.40.50.140	Mainly Beta	Beta Barrel	OB fold (Dihydrolipoamide Acetyltransferase, E2P)	Nucleic acid-binding proteins	CATH (4.3.0)
D	2.40.50.140	Mainly Beta	Beta Barrel	OB fold (Dihydrolipoamide Acetyltransferase, E2P)	Nucleic acid-binding proteins	CATH (4.3.0)
F	2.40.50.140	Mainly Beta	Beta Barrel	OB fold (Dihydrolipoamide Acetyltransferase, E2P)	Nucleic acid-binding proteins	CATH (4.3.0)
G	2.40.50.140	Mainly Beta	Beta Barrel	OB fold (Dihydrolipoamide Acetyltransferase, E2P)	Nucleic acid-binding proteins	CATH (4.3.0)
H	2.40.50.140	Mainly Beta	Beta Barrel	OB fold (Dihydrolipoamide Acetyltransferase, E2P)	Nucleic acid-binding proteins	CATH (4.3.0)
I	2.40.50.140	Mainly Beta	Beta Barrel	OB fold (Dihydrolipoamide Acetyltransferase, E2P)	Nucleic acid-binding proteins	CATH (4.3.0)
J	2.40.50.140	Mainly Beta	Beta Barrel	OB fold (Dihydrolipoamide Acetyltransferase, E2P)	Nucleic acid-binding proteins	CATH (4.3.0)
K	2.40.50.140	Mainly Beta	Beta Barrel	OB fold (Dihydrolipoamide Acetyltransferase, E2P)	Nucleic acid-binding proteins	CATH (4.3.0)
L	2.40.50.140	Mainly Beta	Beta Barrel	OB fold (Dihydrolipoamide Acetyltransferase, E2P)	Nucleic acid-binding proteins	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	PF16450	Proteasomal ATPase OB C-terminal domain (Prot_ATP_ID_OB_C)	Proteasomal ATPase OB C-terminal domain	This is the C-terminal interdomain (ID) or oligonucleotide binding (OB) domain of proteasomal ATPase [1-2]	Domain
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	PF17758	Proteasomal ATPase OB N-terminal domain (Prot_ATP_ID_OB_N)	Proteasomal ATPase OB N-terminal domain	This is N-terminal interdomain (ID), oligonucleotide binding (OB) domain of proteasomal ATPase [1-2].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	Proteasome-associated ATPase	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding protein binding modification-dependent protein binding protein-macromolecule adaptor activity ubiquitin-like protein reader activity molecular adaptor activity pyrophosphatase activity ATP hydrolysis activity ribonucleoside triphosphate phosphatase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides hydrolase activity hydrolase activity, acting on acid anhydrides catalytic activity ATP-dependent activity ATP-dependent peptidase activity peptidase activity catalytic activity, acting on a protein identical protein binding	cellular process protein unfolding response to host defenses biological process involved in interspecies interaction between organisms response to stimulus response to other organism symbiont-mediated perturbation of host defenses response to defenses of other organism response to external stimulus response to biotic stimulus biological process involved in interaction with host biological process involved in symbiotic interaction response to host response to external biotic stimulus cellular process protein unfolding response to host defenses biological process involved in interspecies interaction between organisms response to stimulus response to other organism symbiont-mediated perturbation of host defenses response to defenses of other organism response to external stimulus response to biotic stimulus biological process involved in interaction with host biological process involved in symbiotic interaction response to host response to external biotic stimulus response to nitrosative stress response to stress organonitrogen compound catabolic process organonitrogen compound metabolic process catabolic process proteolysis involved in protein catabolic process proteasomal protein catabolic process primary metabolic process protein catabolic process macromolecule catabolic process organic substance metabolic process proteolysis metabolic process protein metabolic process macromolecule metabolic process organic substance catabolic process modification-dependent macromolecule catabolic process modification-dependent protein catabolic process proteasomal ubiquitin-independent protein catabolic process cellular response to stimulus cellular response to oxidative stress cellular response to chemical stress cellular response to stress response to host immune response symbiont defense to host-produced reactive oxygen species symbiont-mediated perturbation of host innate immune response modulation of process of another organism symbiont-mediated perturbation of host defense response symbiont-mediated perturbation of host immune response response to oxidative stress cellular response to chemical stimulus modulation by symbiont of host process response to chemical cellular response to nitrogen compound cellular response to inorganic substance response to oxygen-containing compound response to nitrogen compound cellular response to oxygen-containing compound response to inorganic substance cellular response to nitric oxide response to nitric oxide cellular response to reactive nitrogen species	proteasome accessory complex protein-containing complex intracellular anatomical structure catalytic complex peptidase complex proteasome complex endopeptidase complex proteasome-activating nucleotidase complex cellular anatomical entity intracellular protein-containing complex cell periphery plasma membrane membrane external encapsulating structure proteasome accessory complex protein-containing complex intracellular anatomical structure catalytic complex peptidase complex proteasome complex endopeptidase complex proteasome-activating nucleotidase complex cellular anatomical entity intracellular protein-containing complex cell periphery plasma membrane membrane external encapsulating structure cell wall peptidoglycan-based cell wall

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR032501	Proteasomal ATPase, second OB domain	Domain
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR022482	Proteasome ATPase	Family
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR003960	ATPase, AAA-type, conserved site	Conserved Site
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR041626	Proteasomal ATPase, N-terminal OB domain	Domain
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR003593	AAA+ ATPase domain	Domain
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR003959	ATPase, AAA-type, core	Domain
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR012340	Nucleic acid-binding, OB-fold	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR027417	P-loop containing nucleoside triphosphate hydrolase	Homologous Superfamily

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3FP9

Crystal structure of Intern Domain of proteasome-associated ATPase, Mycobacterium tuberculosis

External Resource: Annotation

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Domain Annotation: ECOD Classification ECOD Database Homepage

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

InterPro: Protein Family Classification InterPro Database Homepage