3F1C

CRYSTAL STRUCTURE OF 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase from Listeria monocytogenes

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d3f1ca1	Alpha and beta proteins (a/b)	Nucleotide-diphospho-sugar transferases	Nucleotide-diphospho-sugar transferases	automated matches	automated matches	(Listeria monocytogenes serotype 4b str. F2365 ) [TaxId: 265669 ],	SCOPe (2.08)
A	d3f1ca2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Listeria monocytogenes serotype 4b str. F2365 ) [TaxId: 265669 ],	SCOPe (2.08)
B	d3f1cb1	Alpha and beta proteins (a/b)	Nucleotide-diphospho-sugar transferases	Nucleotide-diphospho-sugar transferases	automated matches	automated matches	(Listeria monocytogenes serotype 4b str. F2365 ) [TaxId: 265669 ],	SCOPe (2.08)
B	d3f1cb2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Listeria monocytogenes serotype 4b str. F2365 ) [TaxId: 265669 ],	SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF01128	e3f1cA1	A: a/b three-layered sandwiches	X: Nucleotide-diphospho-sugar transferases (From Topology)	H: Nucleotide-diphospho-sugar transferases (From Topology)	T: Nucleotide-diphospho-sugar transferases	F: PF01128	ECOD (1.6)
B	PF01128	e3f1cB1	A: a/b three-layered sandwiches	X: Nucleotide-diphospho-sugar transferases (From Topology)	H: Nucleotide-diphospho-sugar transferases (From Topology)	T: Nucleotide-diphospho-sugar transferases	F: PF01128	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.90.550.10	Alpha Beta	Alpha-Beta Complex	Spore Coat Polysaccharide Biosynthesis Protein SpsA	Chain A	CATH (4.3.0)
B	3.90.550.10	Alpha Beta	Alpha-Beta Complex	Spore Coat Polysaccharide Biosynthesis Protein SpsA	Chain A	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF01128	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (IspD)	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Putative 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 2	D-ribitol-5-phosphate cytidylyltransferase activity cytidylyltransferase activity transferase activity nucleotidyltransferase activity catalytic activity transferase activity, transferring phosphorus-containing groups	poly(ribitol phosphate) teichoic acid biosynthetic process teichoic acid biosynthetic process cellular biosynthetic process cell wall organization or biogenesis carbohydrate derivative metabolic process organic acid biosynthetic process organic acid metabolic process cellular component biogenesis organic substance metabolic process organic substance biosynthetic process small molecule metabolic process cellular component organization or biogenesis carbohydrate derivative biosynthetic process peptidoglycan-based cell wall biogenesis poly(ribitol phosphate) teichoic acid biosynthetic process teichoic acid biosynthetic process cellular biosynthetic process cell wall organization or biogenesis carbohydrate derivative metabolic process organic acid biosynthetic process organic acid metabolic process cellular component biogenesis organic substance metabolic process organic substance biosynthetic process small molecule metabolic process cellular component organization or biogenesis carbohydrate derivative biosynthetic process peptidoglycan-based cell wall biogenesis small molecule biosynthetic process cellular metabolic process macromolecule biosynthetic process cell wall biogenesis biosynthetic process cell wall macromolecule biosynthetic process cellular process metabolic process poly(ribitol phosphate) teichoic acid metabolic process macromolecule metabolic process teichoic acid metabolic process isoprenoid biosynthetic process lipid biosynthetic process primary metabolic process cellular lipid metabolic process lipid metabolic process isoprenoid metabolic process cellular component organization cell wall organization external encapsulating structure organization	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR034683	Cytidylyltransferase IspD/TarI	Family
A, B	IPR018294	4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site	Conserved Site
A, B	IPR029044	Nucleotide-diphospho-sugar transferases	Homologous Superfamily
A, B	IPR034709	Ribitol-5-phosphate cytidylyltransferase	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.