Annotations: 3E8J

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d3e8ja_	Alpha and beta proteins (a+b)	Coproporphyrinogen III oxidase	Coproporphyrinogen III oxidase	Coproporphyrinogen III oxidase	automated matches	(Leishmania naiffi ) [TaxId: 5678 ],	SCOPe (2.08)
B	d3e8jb_	Alpha and beta proteins (a+b)	Coproporphyrinogen III oxidase	Coproporphyrinogen III oxidase	Coproporphyrinogen III oxidase	automated matches	(Leishmania naiffi ) [TaxId: 5678 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Coproporphyrinogen III oxidase	8076803	3001418	SCOP2B (2022-06-29)
B	SCOP2 Family	Coproporphyrinogen III oxidase	8076802	4001379	SCOP2 (2022-06-29)
B	SCOP2 Superfamily	Coproporphyrinogen III oxidase	8076803	3001418	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Coprogen_oxidas	e3e8jA1	A: a+b three layers	X: Coproporphyrinogen III oxidase (From Topology)	H: Coproporphyrinogen III oxidase (From Topology)	T: Coproporphyrinogen III oxidase	F: Coprogen_oxidas	ECOD (1.6)
B	Coprogen_oxidas	e3e8jB1	A: a+b three layers	X: Coproporphyrinogen III oxidase (From Topology)	H: Coproporphyrinogen III oxidase (From Topology)	T: Coproporphyrinogen III oxidase	F: Coprogen_oxidas	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.1500.10	Alpha Beta	3-Layer(aba) Sandwich	oxygen-dependent coproporphyrinogen oxidase	Coproporphyrinogen III oxidase, aerobic	CATH (4.3.0)
B	3.40.1500.10	Alpha Beta	3-Layer(aba) Sandwich	oxygen-dependent coproporphyrinogen oxidase	Coproporphyrinogen III oxidase, aerobic	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF01218	Coproporphyrinogen III oxidase (Coprogen_oxidas)	Coproporphyrinogen III oxidase	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	COPROPORPHYRINOGEN III OXIDASE	oxidoreductase activity coproporphyrinogen oxidase activity oxidoreductase activity, acting on the CH-CH group of donors catalytic activity oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	pigment metabolic process heme metabolic process porphyrin-containing compound biosynthetic process organonitrogen compound metabolic process tetrapyrrole metabolic process heme biosynthetic process protoporphyrinogen IX metabolic process organonitrogen compound biosynthetic process pigment biosynthetic process organic cyclic compound metabolic process protoporphyrinogen IX biosynthetic process organic substance metabolic process tetrapyrrole biosynthetic process biosynthetic process organic cyclic compound biosynthetic process pigment metabolic process heme metabolic process porphyrin-containing compound biosynthetic process organonitrogen compound metabolic process tetrapyrrole metabolic process heme biosynthetic process protoporphyrinogen IX metabolic process organonitrogen compound biosynthetic process pigment biosynthetic process organic cyclic compound metabolic process protoporphyrinogen IX biosynthetic process organic substance metabolic process tetrapyrrole biosynthetic process biosynthetic process organic cyclic compound biosynthetic process organic substance biosynthetic process metabolic process porphyrin-containing compound metabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR036406	Oxygen-dependent coproporphyrinogen III oxidase superfamily	Homologous Superfamily
A, B	IPR001260	Coproporphyrinogen III oxidase, aerobic	Family
A, B	IPR018375	Coproporphyrinogen III oxidase, conserved site	Conserved Site

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.