Annotations: 3E3X

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	F_UNCLASSIFIED	e3e3xA1	A: a+b two layers	X: Alpha-beta plaits	H: EF-G C-terminal domain-like (From Topology)	T: EF-G C-terminal domain-like	F: F_UNCLASSIFIED	ECOD (1.6)
A	PF00679	e3e3xA2	A: a+b two layers	X: Alpha-beta plaits	H: EF-G C-terminal domain-like (From Topology)	T: EF-G C-terminal domain-like	F: PF00679	ECOD (1.6)
A	PF21018	e3e3xA3	A: a+b complex topology	X: C-terminal domain of BipA (From Topology)	H: C-terminal domain of BipA (From Topology)	T: C-terminal domain of BipA	F: PF21018	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.30.70.870	Alpha Beta	2-Layer Sandwich	Alpha-Beta Plaits	Elongation Factor G (Translational Gtpase), domain 3	CATH (4.3.0)
A	3.30.70.240	Alpha Beta	2-Layer Sandwich	Alpha-Beta Plaits		CATH (4.3.0)
A	2.40.50.250	Mainly Beta	Beta Barrel	OB fold (Dihydrolipoamide Acetyltransferase, E2P)	bipa protein	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF00679	Elongation factor G C-terminus (EFG_C)	Elongation factor G C-terminus	This domain includes the carboxyl terminal regions of Elongation factor G, elongation factor 2 and some tetracycline resistance proteins and adopt a ferredoxin-like fold.	Domain
A	PF21018	TypA/BipA C-terminal domain (BipA_C)	TypA/BipA C-terminal domain	This entry represents the C-terminal domain of the TypA/BipA protein. The C-terminal domain of BipA, consisting of residues, forms a unique motif with two crossed beta sheets (comprising of two and four beta-strands, respectively) wrapped by three sh ...	This entry represents the C-terminal domain of the TypA/BipA protein. The C-terminal domain of BipA, consisting of residues, forms a unique motif with two crossed beta sheets (comprising of two and four beta-strands, respectively) wrapped by three short alpha helices forming a nearly equilateral triangle [1].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	BipA	guanosine tetraphosphate binding guanyl nucleotide binding binding nucleotide binding guanyl ribonucleotide binding purine ribonucleotide binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding guanosine tetraphosphate binding guanyl nucleotide binding binding nucleotide binding guanyl ribonucleotide binding purine ribonucleotide binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding RNA binding rRNA binding nucleic acid binding ribonucleoprotein complex binding protein-containing complex binding ribosome binding tRNA binding GTP binding purine ribonucleoside triphosphate binding pyrophosphatase activity GTPase activity ribonucleoside triphosphate phosphatase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides hydrolase activity hydrolase activity, acting on acid anhydrides catalytic activity	cellular component biogenesis ribosome biogenesis ribonucleoprotein complex biogenesis cellular process cellular component organization or biogenesis	intracellular anatomical structure cytoplasm cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR000795	Translational (tr)-type GTP-binding domain	Domain
A	IPR000640	Elongation factor EFG, domain V-like	Domain
A	IPR047043	GTP-binding protein BipA, domain 3	Domain
A	IPR031157	Tr-type G domain, conserved site	Conserved Site
A	IPR035647	EF-G domain III/V-like	Homologous Superfamily
A	IPR047041	GTP-binding protein BipA, GTP-binding domain	Domain
A	IPR006298	GTP-binding protein BipA	Family
A	IPR042116	GTP-binding protein TypA/BipA, C-terminal	Homologous Superfamily
A	IPR004161	Translation elongation factor EFTu-like, domain 2	Domain
A	IPR047042	GTP-binding protein BipA, domain 2	Domain
A	IPR035651	BipA, domain V	Domain
A	IPR009000	Translation protein, beta-barrel domain superfamily	Homologous Superfamily
A	IPR005225	Small GTP-binding protein domain	Domain
A	IPR048876	TypA/BipA, C-terminal domain	Domain
A	IPR027417	P-loop containing nucleoside triphosphate hydrolase	Homologous Superfamily

Protein Modification Annotation

Modified Residue(s)
Chain	Residue(s)	Description
A	MLY	Parent Component: LYS RESID: AA0075 PSI-MOD : N6,N6-dimethyl-L-lysine MOD:00084
A	MLZ	Parent Component: LYS RESID: AA0075 , AA0076 PSI-MOD : N6,N6-dimethyl-L-lysine MOD:00084 , N6-methyl-L-lysine MOD:00085
A	MSE	Parent Component: MET RESID: AA0075 , AA0076

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.