3DJC

CRYSTAL STRUCTURE OF PANTOTHENATE KINASE FROM LEGIONELLA PNEUMOPHILA

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d3djca1	Alpha and beta proteins (a/b)	Ribonuclease H-like motif	Actin-like ATPase domain	automated matches	automated matches	(Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ) [TaxId: 272624 ],	SCOPe (2.08)
A	d3djca3	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ) [TaxId: 272624 ],	SCOPe (2.08)
B	d3djcb1	Alpha and beta proteins (a/b)	Ribonuclease H-like motif	Actin-like ATPase domain	automated matches	automated matches	(Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ) [TaxId: 272624 ],	SCOPe (2.08)
B	d3djcb3	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ) [TaxId: 272624 ],	SCOPe (2.08)
C	d3djcc1	Alpha and beta proteins (a/b)	Ribonuclease H-like motif	Actin-like ATPase domain	automated matches	automated matches	(Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ) [TaxId: 272624 ],	SCOPe (2.08)
C	d3djcc3	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ) [TaxId: 272624 ],	SCOPe (2.08)
D	d3djcd1	Alpha and beta proteins (a/b)	Ribonuclease H-like motif	Actin-like ATPase domain	automated matches	automated matches	(Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ) [TaxId: 272624 ],	SCOPe (2.08)
D	d3djcd3	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ) [TaxId: 272624 ],	SCOPe (2.08)
E	d3djce1	Alpha and beta proteins (a/b)	Ribonuclease H-like motif	Actin-like ATPase domain	automated matches	automated matches	(Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ) [TaxId: 272624 ],	SCOPe (2.08)
E	d3djce3	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ) [TaxId: 272624 ],	SCOPe (2.08)
F	d3djcf1	Alpha and beta proteins (a/b)	Ribonuclease H-like motif	Actin-like ATPase domain	automated matches	automated matches	(Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ) [TaxId: 272624 ],	SCOPe (2.08)
F	d3djcf3	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ) [TaxId: 272624 ],	SCOPe (2.08)
G	d3djcg1	Alpha and beta proteins (a/b)	Ribonuclease H-like motif	Actin-like ATPase domain	automated matches	automated matches	(Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ) [TaxId: 272624 ],	SCOPe (2.08)
G	d3djcg3	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ) [TaxId: 272624 ],	SCOPe (2.08)
H	d3djch1	Alpha and beta proteins (a/b)	Ribonuclease H-like motif	Actin-like ATPase domain	automated matches	automated matches	(Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ) [TaxId: 272624 ],	SCOPe (2.08)
H	d3djch3	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ) [TaxId: 272624 ],	SCOPe (2.08)
I	d3djci1	Alpha and beta proteins (a/b)	Ribonuclease H-like motif	Actin-like ATPase domain	automated matches	automated matches	(Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ) [TaxId: 272624 ],	SCOPe (2.08)
I	d3djci3	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ) [TaxId: 272624 ],	SCOPe (2.08)
J	d3djcj1	Alpha and beta proteins (a/b)	Ribonuclease H-like motif	Actin-like ATPase domain	automated matches	automated matches	(Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ) [TaxId: 272624 ],	SCOPe (2.08)
J	d3djcj3	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ) [TaxId: 272624 ],	SCOPe (2.08)
K	d3djck1	Alpha and beta proteins (a/b)	Ribonuclease H-like motif	Actin-like ATPase domain	automated matches	automated matches	(Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ) [TaxId: 272624 ],	SCOPe (2.08)
K	d3djck3	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ) [TaxId: 272624 ],	SCOPe (2.08)
L	d3djcl1	Alpha and beta proteins (a/b)	Ribonuclease H-like motif	Actin-like ATPase domain	automated matches	automated matches	(Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ) [TaxId: 272624 ],	SCOPe (2.08)
L	d3djcl3	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ) [TaxId: 272624 ],	SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Pan_kinase_C	e3djcA4	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: Pan_kinase_C	ECOD (1.6)
A	Pan_kinase_N	e3djcA3	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: Pan_kinase_N	ECOD (1.6)
B	Pan_kinase_C	e3djcB4	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: Pan_kinase_C	ECOD (1.6)
B	Pan_kinase_N	e3djcB3	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: Pan_kinase_N	ECOD (1.6)
C	Pan_kinase_C	e3djcC4	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: Pan_kinase_C	ECOD (1.6)
C	Pan_kinase_N	e3djcC3	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: Pan_kinase_N	ECOD (1.6)
D	Pan_kinase_C	e3djcD4	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: Pan_kinase_C	ECOD (1.6)
D	Pan_kinase_N	e3djcD3	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: Pan_kinase_N	ECOD (1.6)
E	Pan_kinase_C	e3djcE4	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: Pan_kinase_C	ECOD (1.6)
E	Pan_kinase_N	e3djcE3	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: Pan_kinase_N	ECOD (1.6)
F	Pan_kinase_C	e3djcF4	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: Pan_kinase_C	ECOD (1.6)
F	Pan_kinase_N	e3djcF3	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: Pan_kinase_N	ECOD (1.6)
G	Pan_kinase_C	e3djcG4	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: Pan_kinase_C	ECOD (1.6)
G	Pan_kinase_N	e3djcG3	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: Pan_kinase_N	ECOD (1.6)
H	Pan_kinase_C	e3djcH4	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: Pan_kinase_C	ECOD (1.6)
H	Pan_kinase_N	e3djcH3	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: Pan_kinase_N	ECOD (1.6)
I	Pan_kinase_C	e3djcI4	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: Pan_kinase_C	ECOD (1.6)
I	Pan_kinase_N	e3djcI3	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: Pan_kinase_N	ECOD (1.6)
J	Pan_kinase_C	e3djcJ4	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: Pan_kinase_C	ECOD (1.6)
J	Pan_kinase_N	e3djcJ3	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: Pan_kinase_N	ECOD (1.6)
K	Pan_kinase_C	e3djcK4	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: Pan_kinase_C	ECOD (1.6)
K	Pan_kinase_N	e3djcK3	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: Pan_kinase_N	ECOD (1.6)
L	Pan_kinase_C	e3djcL4	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: Pan_kinase_C	ECOD (1.6)
L	Pan_kinase_N	e3djcL3	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: Pan_kinase_N	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.30.420.40	Alpha Beta	2-Layer Sandwich	Nucleotidyltransferase	domain 5	CATH (4.3.0)
B	3.30.420.40	Alpha Beta	2-Layer Sandwich	Nucleotidyltransferase	domain 5	CATH (4.3.0)
C	3.30.420.40	Alpha Beta	2-Layer Sandwich	Nucleotidyltransferase	domain 5	CATH (4.3.0)
D	3.30.420.40	Alpha Beta	2-Layer Sandwich	Nucleotidyltransferase	domain 5	CATH (4.3.0)
E	3.30.420.40	Alpha Beta	2-Layer Sandwich	Nucleotidyltransferase	domain 5	CATH (4.3.0)
F	3.30.420.40	Alpha Beta	2-Layer Sandwich	Nucleotidyltransferase	domain 5	CATH (4.3.0)
G	3.30.420.40	Alpha Beta	2-Layer Sandwich	Nucleotidyltransferase	domain 5	CATH (4.3.0)
H	3.30.420.40	Alpha Beta	2-Layer Sandwich	Nucleotidyltransferase	domain 5	CATH (4.3.0)
I	3.30.420.40	Alpha Beta	2-Layer Sandwich	Nucleotidyltransferase	domain 5	CATH (4.3.0)
J	3.30.420.40	Alpha Beta	2-Layer Sandwich	Nucleotidyltransferase	domain 5	CATH (4.3.0)
K	3.30.420.40	Alpha Beta	2-Layer Sandwich	Nucleotidyltransferase	domain 5	CATH (4.3.0)
L	3.30.420.40	Alpha Beta	2-Layer Sandwich	Nucleotidyltransferase	domain 5	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	PF03309	Type III pantothenate kinase (Pan_kinase)	Type III pantothenate kinase	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	Type III pantothenate kinase	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding kinase activity transferase activity catalytic activity pantothenate kinase activity phosphotransferase activity, alcohol group as acceptor transferase activity, transferring phosphorus-containing groups cation binding metal ion binding	phosphorylation cellular metabolic process phosphate-containing compound metabolic process metabolic process cellular process phosphorus metabolic process ribose phosphate metabolic process nucleoside bisphosphate metabolic process coenzyme A biosynthetic process ribonucleoside bisphosphate biosynthetic process purine nucleoside bisphosphate metabolic process ribonucleoside bisphosphate metabolic process nucleotide biosynthetic process organonitrogen compound biosynthetic process phosphorylation cellular metabolic process phosphate-containing compound metabolic process metabolic process cellular process phosphorus metabolic process ribose phosphate metabolic process nucleoside bisphosphate metabolic process coenzyme A biosynthetic process ribonucleoside bisphosphate biosynthetic process purine nucleoside bisphosphate metabolic process ribonucleoside bisphosphate metabolic process nucleotide biosynthetic process organonitrogen compound biosynthetic process carbohydrate derivative metabolic process purine ribonucleotide biosynthetic process nucleobase-containing compound metabolic process ribonucleotide biosynthetic process purine nucleotide metabolic process organic substance metabolic process ribonucleotide metabolic process nucleobase-containing small molecule metabolic process purine-containing compound biosynthetic process organic substance biosynthetic process small molecule metabolic process purine nucleoside bisphosphate biosynthetic process ribose phosphate biosynthetic process coenzyme A metabolic process nucleoside phosphate metabolic process carbohydrate derivative biosynthetic process organonitrogen compound metabolic process nucleoside bisphosphate biosynthetic process primary metabolic process nucleotide metabolic process nucleobase-containing compound biosynthetic process purine-containing compound metabolic process organic cyclic compound metabolic process biosynthetic process organophosphate metabolic process organophosphate biosynthetic process organic cyclic compound biosynthetic process nucleoside phosphate biosynthetic process purine ribonucleotide metabolic process purine nucleotide biosynthetic process	intracellular anatomical structure cytoplasm cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR004619	Type III pantothenate kinase	Family
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR043129	ATPase, nucleotide binding domain	Homologous Superfamily