3CNV

Crystal structure of the ligand-binding domain of a putative GntR-family transcriptional regulator from Bordetella bronchiseptica

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d3cnva1	Alpha and beta proteins (a+b)	Chorismate lyase-like	Chorismate lyase-like	UTRA domain	Putative transcriptional regulator BB3683	(Bordetella bronchiseptica RB50 ) [TaxId: 257310 ],	SCOPe (2.08)
B	d3cnvb_	Alpha and beta proteins (a+b)	Chorismate lyase-like	Chorismate lyase-like	UTRA domain	Putative transcriptional regulator BB3683	(Bordetella bronchiseptica RB50 ) [TaxId: 257310 ],	SCOPe (2.08)
C	d3cnvc_	Alpha and beta proteins (a+b)	Chorismate lyase-like	Chorismate lyase-like	UTRA domain	Putative transcriptional regulator BB3683	(Bordetella bronchiseptica RB50 ) [TaxId: 257310 ],	SCOPe (2.08)
D	d3cnvd_	Alpha and beta proteins (a+b)	Chorismate lyase-like	Chorismate lyase-like	UTRA domain	Putative transcriptional regulator BB3683	(Bordetella bronchiseptica RB50 ) [TaxId: 257310 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Chorismate lyase-like	8040196	3000072	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Chorismate lyase-like	8040196	3000072	SCOP2B (2022-06-29)
C	SCOP2 Family	UTRA domain	8027817	4000314	SCOP2 (2022-06-29)
C	SCOP2 Superfamily	Chorismate lyase-like	8040196	3000072	SCOP2 (2022-06-29)
D	SCOP2B Superfamily	Chorismate lyase-like	8040196	3000072	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	UTRA	e3cnvA1	A: a+b two layers	X: Chorismate lyase (From Topology)	H: Chorismate lyase (From Topology)	T: Chorismate lyase	F: UTRA	ECOD (1.6)
B	UTRA	e3cnvB1	A: a+b two layers	X: Chorismate lyase (From Topology)	H: Chorismate lyase (From Topology)	T: Chorismate lyase	F: UTRA	ECOD (1.6)
C	UTRA	e3cnvC1	A: a+b two layers	X: Chorismate lyase (From Topology)	H: Chorismate lyase (From Topology)	T: Chorismate lyase	F: UTRA	ECOD (1.6)
D	UTRA	e3cnvD1	A: a+b two layers	X: Chorismate lyase (From Topology)	H: Chorismate lyase (From Topology)	T: Chorismate lyase	F: UTRA	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.1410.10	Alpha Beta	3-Layer(aba) Sandwich	Chorismate lyase	Chorismate lyase-like	CATH (4.3.0)
B	3.40.1410.10	Alpha Beta	3-Layer(aba) Sandwich	Chorismate lyase	Chorismate lyase-like	CATH (4.3.0)
C	3.40.1410.10	Alpha Beta	3-Layer(aba) Sandwich	Chorismate lyase	Chorismate lyase-like	CATH (4.3.0)
D	3.40.1410.10	Alpha Beta	3-Layer(aba) Sandwich	Chorismate lyase	Chorismate lyase-like	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF07702	UTRA domain (UTRA)	UTRA domain	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain that has a similar fold to Pfam:PF04345 [1]. It is believed to modulate activity of bacterial transcription factors in response to binding small molecules ...	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain that has a similar fold to Pfam:PF04345 [1]. It is believed to modulate activity of bacterial transcription factors in response to binding small molecules [1] sugar phosphates and urocanate, Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	Putative GntR-family transcriptional regulator	DNA binding binding organic cyclic compound binding nucleic acid binding transcription regulator activity DNA-binding transcription factor activity	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D	IPR011663	UbiC transcription regulator-associated	Domain
A, B, C, D	IPR028978	Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily	Homologous Superfamily
A, B, C, D	IPR036388	Winged helix-like DNA-binding domain superfamily	Homologous Superfamily
A, B, C, D	IPR000524	Transcription regulator HTH, GntR	Domain
A, B, C, D	IPR036390	Winged helix DNA-binding domain superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.