3CGW

Crystal structure of 2-phospho-(S)-lactate transferase from Methanosarcina mazei. Northeast Structural Genomics Consortium target MaR46

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d3cgwa_	Alpha and beta proteins (a/b)	CofD-like	CofD-like	CofD-like	LPPG:FO 2-phospho-L-lactate transferase CofD	(Methanosarcina mazei Go1 ) [TaxId: 192952 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	CofD-like	8028478	4002881	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	CofD-like	8040857	3001842	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	UPF0052	e3cgwA1	A: a/b three-layered sandwiches	X: CofD-like (From Topology)	H: CofD-like (From Topology)	T: CofD-like	F: UPF0052	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.50.10680	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	CofD-like domains	CATH (4.3.0)
A	1.10.8.240	Mainly Alpha	Orthogonal Bundle	Helicase, Ruva Protein	domain 3	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF01933	2-phospho-L-lactate transferase CofD (CofD)	2-phospho-L-lactate transferase CofD	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	LPPG:FO 2-phospho-L-lactate transferase	cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding LPPG:FO 2-phospho-L-lactate transferase activity transferase activity catalytic activity phosphotransferase activity, alcohol group as acceptor transferase activity, transferring phosphorus-containing groups	carbohydrate metabolic process organonitrogen compound metabolic process oxoacid metabolic process cellular metabolic process carboxylic acid metabolic process pentitol phosphate metabolic process carbohydrate derivative metabolic process primary metabolic process organic acid metabolic process aldonic acid metabolic process organic cyclic compound metabolic process organic substance metabolic process ribitol phosphate metabolic process organophosphate metabolic process F420-0 metabolic process carbohydrate metabolic process organonitrogen compound metabolic process oxoacid metabolic process cellular metabolic process carboxylic acid metabolic process pentitol phosphate metabolic process carbohydrate derivative metabolic process primary metabolic process organic acid metabolic process aldonic acid metabolic process organic cyclic compound metabolic process organic substance metabolic process ribitol phosphate metabolic process organophosphate metabolic process F420-0 metabolic process phosphate-containing compound metabolic process metabolic process small molecule metabolic process cellular process monocarboxylic acid metabolic process alditol phosphate metabolic process phosphorus metabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR010115	Phosphoenolpyruvate transferase/2-phospho-L-lactate transferase	Family
A	IPR038136	CofD-like domain superfamily	Homologous Superfamily
A	IPR002882	2-phospho-L-lactate transferase CofD	Family

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.