Annotations: 3CEQ

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF13424	e3ceqA1	A: alpha superhelices	X: Repetitive alpha hairpins	H: ARM repeat (From Topology)	T: ARM repeat	F: PF13424	ECOD (1.6)
B	PF13424	e3ceqB1	A: alpha superhelices	X: Repetitive alpha hairpins	H: ARM repeat (From Topology)	T: ARM repeat	F: PF13424	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.25.40.10	Mainly Alpha	Alpha Horseshoe	Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat	Tetratricopeptide repeat domain	CATH (4.3.0)
B	1.25.40.10	Mainly Alpha	Alpha Horseshoe	Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat	Tetratricopeptide repeat domain	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF13424	Tetratricopeptide repeat (TPR_12)	Tetratricopeptide repeat	-	Repeat

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Kinesin light chain 2	cell adhesion molecule binding cadherin binding protein binding binding cytoskeletal protein binding kinesin binding	microtubule-based movement microtubule-based process cellular process localization organelle localization lysosome localization vacuolar localization	membrane-bounded organelle intracellular organelle intracellular anatomical structure mitochondrion organelle cytoplasm cellular anatomical entity intracellular membrane-bounded organelle vacuolar membrane membrane lytic vacuole vacuole lytic vacuole membrane bounding membrane of organelle membrane-bounded organelle intracellular organelle intracellular anatomical structure mitochondrion organelle cytoplasm cellular anatomical entity intracellular membrane-bounded organelle vacuolar membrane membrane lytic vacuole vacuole lytic vacuole membrane bounding membrane of organelle lysosomal membrane organelle membrane lysosome cytosol protein-containing complex cytoskeleton intracellular non-membrane-bounded organelle kinesin I complex microtubule associated complex kinesin complex microtubule cytoskeleton non-membrane-bounded organelle cell periphery plasma membrane nucleus membrane-enclosed lumen intracellular organelle lumen nucleoplasm organelle lumen nuclear lumen polymeric cytoskeletal fiber supramolecular fiber microtubule supramolecular polymer supramolecular complex

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR011990	Tetratricopeptide-like helical domain superfamily	Homologous Superfamily
A, B	IPR002151	Kinesin light chain	Family
A, B	IPR015792	Kinesin light chain repeat	Repeat
A, B	IPR019734	Tetratricopeptide repeat	Repeat

Pharos: Disease Associations Pharos Homepage Annotation

Chains	Drug Target	Associated Disease
A, B	Pharos: Q9H0B6	SPOAN syndrome hereditary spastic paraplegia peripheral neuropathy astrocytic tumor breast carcinoma malignant glioma oligodendroglioma peripheral nervous system disease prostate carcinoma atypical teratoid rhabdoid tumor glioblastoma lung carcinoma medulloblastoma ovarian carcinoma bipolar disorder SPOAN syndrome hereditary spastic paraplegia peripheral neuropathy astrocytic tumor breast carcinoma malignant glioma oligodendroglioma peripheral nervous system disease prostate carcinoma atypical teratoid rhabdoid tumor glioblastoma lung carcinoma medulloblastoma ovarian carcinoma bipolar disorder gout malignant ependymoma neurodegenerative disease paraplegia pilocytic astrocytoma

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.