3BZL

Crystal structural of native EscU C-terminal domain

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d3bzl.1	Alpha and beta proteins (a+b)	EscU C-terminal domain-like	EscU C-terminal domain-like	EscU C-terminal domain-like	Type III secretion proteins EscU	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
B [auth C]	d3bzl.1	Alpha and beta proteins (a+b)	EscU C-terminal domain-like	EscU C-terminal domain-like	EscU C-terminal domain-like	Type III secretion proteins EscU	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
B [auth C]	SCOP2B Superfamily	EscU C-terminal domain-like	8039656	3000928	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	EscU C-terminal domain-like	8039656	3000928	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
C [auth B]	PF01312	e3bzlB1	A: beta sandwiches	X: EscU C-terminal domain-like (From Topology)	H: EscU C-terminal domain-like (From Topology)	T: EscU C-terminal domain-like	F: PF01312	ECOD (1.6)
D	PF01312	e3bzlD1	A: beta sandwiches	X: EscU C-terminal domain-like (From Topology)	H: EscU C-terminal domain-like (From Topology)	T: EscU C-terminal domain-like	F: PF01312	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
B [auth C]	3.40.1690.10	Alpha Beta	3-Layer(aba) Sandwich	name from scop	secretion proteins EscU	CATH (4.3.0)
D	3.40.1690.10	Alpha Beta	3-Layer(aba) Sandwich	name from scop	secretion proteins EscU	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, C [auth B]	PF01312	FlhB HrpN YscU SpaS Family (Bac_export_2)	FlhB HrpN YscU SpaS Family	-	Family
B [auth C], D	PF01312	FlhB HrpN YscU SpaS Family (Bac_export_2)	FlhB HrpN YscU SpaS Family	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, C [auth B]	EscU	isomerase activity catalytic activity oxidoreductase activity dioxygenase activity	protein localization establishment of protein localization cellular localization nitrogen compound transport transport secretion organic substance transport establishment of protein localization to extracellular region export from cell protein secretion establishment of localization protein localization to extracellular region localization secretion by cell protein transport protein localization establishment of protein localization cellular localization nitrogen compound transport transport secretion organic substance transport establishment of protein localization to extracellular region export from cell protein secretion establishment of localization protein localization to extracellular region localization secretion by cell protein transport cellular macromolecule localization macromolecule localization cellular process	cell periphery plasma membrane membrane cellular anatomical entity
B [auth C], D	EscU	isomerase activity catalytic activity oxidoreductase activity dioxygenase activity	protein localization establishment of protein localization cellular localization nitrogen compound transport transport secretion organic substance transport establishment of protein localization to extracellular region export from cell protein secretion establishment of localization protein localization to extracellular region localization secretion by cell protein transport protein localization establishment of protein localization cellular localization nitrogen compound transport transport secretion organic substance transport establishment of protein localization to extracellular region export from cell protein secretion establishment of localization protein localization to extracellular region localization secretion by cell protein transport cellular macromolecule localization macromolecule localization cellular process	cell periphery plasma membrane membrane cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, C [auth B]	IPR006135	Type III secretion system substrate exporter	Family
A, C [auth B]	IPR006307	Type III exporter system, secretion apparatus protein BsaZ-like	Family
A, C [auth B]	IPR029025	Type III secretion system substrate exporter, C-terminal	Homologous Superfamily
B [auth C], D	IPR006135	Type III secretion system substrate exporter	Family
B [auth C], D	IPR006307	Type III exporter system, secretion apparatus protein BsaZ-like	Family
B [auth C], D	IPR029025	Type III secretion system substrate exporter, C-terminal	Homologous Superfamily

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.