3BZK

Crystal Structure of the Tex protein from Pseudomonas aeruginosa, crystal form 2

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d3bzka1	All alpha proteins	SAM domain-like	RuvA domain 2-like	Tex HhH-containing domain-like	Transcriptional accessory factor Tex	(Pseudomonas aeruginosa ) [TaxId: 287 ],	SCOPe (2.08)
A	d3bzka3	All alpha proteins	Tex N-terminal region-like	Tex N-terminal region-like	Tex N-terminal region-like	Transcriptional accessory factor Tex	(Pseudomonas aeruginosa ) [TaxId: 287 ],	SCOPe (2.08)
A	d3bzka4	All beta proteins	OB-fold	Nucleic acid-binding proteins	Cold shock DNA-binding domain-like	Tex S1-domain	(Pseudomonas aeruginosa ) [TaxId: 287 ],	SCOPe (2.08)
A	d3bzka5	Alpha and beta proteins (a/b)	Ribonuclease H-like motif	Ribonuclease H-like	Tex RuvX-like domain-like	Transcriptional accessory factor Tex	(Pseudomonas aeruginosa ) [TaxId: 287 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Helix-hairpin-helix tandem	8039622	3000163	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	Ribonuclease H-like	8039631	3000143	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	Nucleic acid-binding proteins	8039630	3000135	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	Tex N-terminal region-like	8039629	3001958	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	Helix-hairpin-helix tandem	8039626	3000163	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF00575	e3bzkA1	A: beta barrels	X: OB-fold	H: Nucleic acid-binding proteins (From Topology)	T: Nucleic acid-binding proteins	F: PF00575	ECOD (1.6)
A	PF09371	e3bzkA2	A: alpha arrays	X: HTH	H: Tex N-terminal domain (From Topology)	T: Tex N-terminal domain	F: PF09371	ECOD (1.6)
A	PF12836	e3bzkA3	A: alpha arrays	X: HhH/H2TH	H: SAM/DNA-glycosylase	T: SAM domain-like	F: PF12836	ECOD (1.6)
A	PF17674	e3bzkA4	A: alpha arrays	X: HhH/H2TH	H: SAM/DNA-glycosylase	T: SAM domain-like	F: PF17674	ECOD (1.6)
A	F_UNCLASSIFIED	e3bzkA5	A: alpha bundles	X: immunoglobulin/albumin-binding domain-like	H: Tex bundle domain-like (From Topology)	T: Tex bundle domain-like	F: F_UNCLASSIFIED	ECOD (1.6)
A	PF22706	e3bzkA6	A: alpha complex topology	X: Tex N-terminal region-like (From Topology)	H: Tex N-terminal region-like (From Topology)	T: Tex N-terminal region-like	F: PF22706	ECOD (1.6)
A	PF16921	e3bzkA7	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: PF16921	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.10.10.650	Mainly Alpha	Orthogonal Bundle	Arc Repressor Mutant, subunit A	RuvA domain 2-like	CATH (4.3.0)
A	1.10.3500.10	Mainly Alpha	Orthogonal Bundle	Tex N-terminal region-like	Tex N-terminal region-like	CATH (4.3.0)
A	3.30.420.140	Alpha Beta	2-Layer Sandwich	Nucleotidyltransferase	domain 5	CATH (4.3.0)
A	1.10.150.310	Mainly Alpha	Orthogonal Bundle	DNA polymerase	domain 1	CATH (4.3.0)
A	2.40.50.140	Mainly Beta	Beta Barrel	OB fold (Dihydrolipoamide Acetyltransferase, E2P)	Nucleic acid-binding proteins	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF17674	HHH domain (HHH_9)	HHH domain	-	Domain
A	PF09371	Tex-like protein N-terminal domain (Tex_N)	Tex-like protein N-terminal domain	This presumed domain is found at the N-terminus of Swiss:Q45388. This protein defines a novel family of prokaryotic transcriptional accessory factors [1].	Domain
A	PF12836	Helix-hairpin-helix motif (HHH_3)	Helix-hairpin-helix motif	The HhH domain is a short DNA-binding domain [2].	Domain
A	PF16921	Tex protein YqgF-like domain (Tex_YqgF)	Tex protein YqgF-like domain	This is the YqgF-like domain of the bacterial Tex protein, which is involved in transcriptional processes [1].	Domain
A	PF00575	S1 RNA binding domain (S1)	S1 RNA binding domain	The S1 domain occurs in a wide range of RNA associated proteins. It is structurally similar to cold shock protein which binds nucleic acids. The S1 domain has an OB-fold structure.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Tex	RNA binding binding organic cyclic compound binding nucleic acid binding mRNA binding structural molecule activity structural constituent of ribosome	nucleobase-containing compound metabolic process organic cyclic compound metabolic process organic substance metabolic process metabolic process primary metabolic process organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process organonitrogen compound biosynthetic process translation gene expression macromolecule biosynthetic process biosynthetic process organic substance biosynthetic process nucleobase-containing compound metabolic process organic cyclic compound metabolic process organic substance metabolic process metabolic process primary metabolic process organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process organonitrogen compound biosynthetic process translation gene expression macromolecule biosynthetic process biosynthetic process organic substance biosynthetic process cellular process protein metabolic process macromolecule metabolic process	intracellular anatomical structure cytoplasm cellular anatomical entity cytosol

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR018974	Tex-like protein, N-terminal	Domain
A	IPR003029	S1 domain	Domain
A	IPR037027	YqgF/RNase H-like domain superfamily	Homologous Superfamily
A	IPR023323	Tex-like domain superfamily	Homologous Superfamily
A	IPR006641	YqgF/RNase H-like domain	Domain
A	IPR041692	HHH domain 9	Domain
A	IPR010994	RuvA domain 2-like	Homologous Superfamily
A	IPR032639	Tex protein, YqgF-like domain	Domain
A	IPR012340	Nucleic acid-binding, OB-fold	Homologous Superfamily
A	IPR023319	Tex-like protein, HTH domain superfamily	Homologous Superfamily
A	IPR044146	Tex, S1 domain	Domain
A	IPR012337	Ribonuclease H-like superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.