3BXZ
Crystal structure of the isolated DEAD motor domains from Escherichia coli SecA
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
B | PF07517 | e3bxzB3 | A: a/b three-layered sandwiches | X: P-loop domains-like | H: P-loop domains-related | T: P-loop containing nucleoside triphosphate hydrolases | F: PF07517 | ECOD (1.6) |
B | PF21090 | e3bxzB4 | A: a/b three-layered sandwiches | X: P-loop domains-like | H: P-loop domains-related | T: P-loop containing nucleoside triphosphate hydrolases | F: PF21090 | ECOD (1.6) |
A | PF07517 | e3bxzA3 | A: a/b three-layered sandwiches | X: P-loop domains-like | H: P-loop domains-related | T: P-loop containing nucleoside triphosphate hydrolases | F: PF07517 | ECOD (1.6) |
A | PF21090 | e3bxzA4 | A: a/b three-layered sandwiches | X: P-loop domains-like | H: P-loop domains-related | T: P-loop containing nucleoside triphosphate hydrolases | F: PF21090 | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
B | 3.40.50.300 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | P-loop containing nucleotide triphosphate hydrolases | CATH (4.3.0) |
A | 3.40.50.300 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | P-loop containing nucleotide triphosphate hydrolases | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF07517 | SecA DEAD-like domain (SecA_DEAD) | SecA DEAD-like domain | SecA protein binds to the plasma membrane where it interacts with proOmpA to support translocation of proOmpA through the membrane. SecA protein achieves this translocation, in association with SecY protein, in an ATP dependent manner [1,2]. This do ... | Domain | |
PF21090 | SecA P-loop domain (P-loop_SecA) | SecA P-loop domain | SecA is the preprotein translocase ATPase subunit and a superfamily 2 (SF2) RNA helicase [4]. This entry corresponds to the second P-loop domain. | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR011130 | SecA, preprotein cross-linking domain | Domain | |
IPR011116 | SecA Wing/Scaffold | Domain | |
IPR014018 | SecA motor DEAD | Domain | |
IPR020937 | SecA conserved site | Conserved Site | |
IPR044722 | SecA, C-terminal helicase domain | Domain | |
IPR027417 | P-loop containing nucleoside triphosphate hydrolase | Homologous Superfamily | |
IPR036670 | SecA, preprotein cross-linking domain superfamily | Homologous Superfamily | |
IPR036266 | SecA, Wing/Scaffold superfamily | Homologous Superfamily | |
IPR001650 | Helicase, C-terminal domain-like | Domain | |
IPR000185 | Protein translocase subunit SecA | Family | |
IPR014001 | Helicase superfamily 1/2, ATP-binding domain | Domain | |
IPR004027 | SEC-C motif | Conserved Site | |
IPR011115 | SecA DEAD-like, N-terminal | Domain |