3BU2

Crystal structure of a tRNA-binding protein from Staphylococcus saprophyticus subsp. saprophyticus. Northeast Structural Genomics Consortium target SyR77

External Resource: Annotation

Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
B	tRNA_bind_1	e3bu2B2	A: beta barrels	X: OB-fold	H: Nucleic acid-binding proteins (From Topology)	T: Nucleic acid-binding proteins	F: tRNA_bind_1	ECOD (1.6)
B	DUF4479	e3bu2B1	A: a+b two layers	X: DUF4479 (From Topology)	H: DUF4479 (From Topology)	T: DUF4479	F: DUF4479	ECOD (1.6)
A	tRNA_bind_1	e3bu2A2	A: beta barrels	X: OB-fold	H: Nucleic acid-binding proteins (From Topology)	T: Nucleic acid-binding proteins	F: tRNA_bind_1	ECOD (1.6)
A	DUF4479	e3bu2A1	A: a+b two layers	X: DUF4479 (From Topology)	H: DUF4479 (From Topology)	T: DUF4479	F: DUF4479	ECOD (1.6)
C	tRNA_bind_1	e3bu2C2	A: beta barrels	X: OB-fold	H: Nucleic acid-binding proteins (From Topology)	T: Nucleic acid-binding proteins	F: tRNA_bind_1	ECOD (1.6)
C	DUF4479	e3bu2C1	A: a+b two layers	X: DUF4479 (From Topology)	H: DUF4479 (From Topology)	T: DUF4479	F: DUF4479	ECOD (1.6)
D	tRNA_bind_1	e3bu2D2	A: beta barrels	X: OB-fold	H: Nucleic acid-binding proteins (From Topology)	T: Nucleic acid-binding proteins	F: tRNA_bind_1	ECOD (1.6)
D	DUF4479	e3bu2D1	A: a+b two layers	X: DUF4479 (From Topology)	H: DUF4479 (From Topology)	T: DUF4479	F: DUF4479	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
B	2.40.50.140	Mainly Beta	Beta Barrel	OB fold (Dihydrolipoamide Acetyltransferase, E2P)	Nucleic acid-binding proteins	CATH (4.3.0)
B	3.30.1940.10	Alpha Beta	2-Layer Sandwich	Nucleic acid-binding protein fold	YtpR-like	CATH (4.3.0)
A	2.40.50.140	Mainly Beta	Beta Barrel	OB fold (Dihydrolipoamide Acetyltransferase, E2P)	Nucleic acid-binding proteins	CATH (4.3.0)
A	3.30.1940.10	Alpha Beta	2-Layer Sandwich	Nucleic acid-binding protein fold	YtpR-like	CATH (4.3.0)
C	2.40.50.140	Mainly Beta	Beta Barrel	OB fold (Dihydrolipoamide Acetyltransferase, E2P)	Nucleic acid-binding proteins	CATH (4.3.0)
C	3.30.1940.10	Alpha Beta	2-Layer Sandwich	Nucleic acid-binding protein fold	YtpR-like	CATH (4.3.0)
D	2.40.50.140	Mainly Beta	Beta Barrel	OB fold (Dihydrolipoamide Acetyltransferase, E2P)	Nucleic acid-binding proteins	CATH (4.3.0)
D	3.30.1940.10	Alpha Beta	2-Layer Sandwich	Nucleic acid-binding protein fold	YtpR-like	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF14794	Domain of unknown function (DUF4479) (DUF4479)	Domain of unknown function (DUF4479)	-	Family
A, B, C, D	PF01588	Putative tRNA binding domain (tRNA_bind)	Putative tRNA binding domain	This domain is found in prokaryotic methionyl-tRNA synthetases, prokaryotic phenylalanyl tRNA synthetases the yeast GU4 nucleic-binding protein (G4p1 or p42, ARC1) [2], human tyrosyl-tRNA synthetase [1], and endothelial-monocyte activating polypept ...	This domain is found in prokaryotic methionyl-tRNA synthetases, prokaryotic phenylalanyl tRNA synthetases the yeast GU4 nucleic-binding protein (G4p1 or p42, ARC1) [2], human tyrosyl-tRNA synthetase [1], and endothelial-monocyte activating polypeptide II. G4p1 binds specifically to tRNA form a complex with methionyl-tRNA synthetases [2]. In human tyrosyl-tRNA synthetase this domain may direct tRNA to the active site of the enzyme [2]. This domain may perform a common function in tRNA aminoacylation [1].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	Putative tRNA-binding protein	RNA binding binding organic cyclic compound binding tRNA binding nucleic acid binding	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D	IPR033714	Phenylalanly tRNA synthetase, tRNA-binding-domain	Domain
A, B, C, D	IPR027855	Domain of unknown function DUF4479	Domain
A, B, C, D	IPR012340	Nucleic acid-binding, OB-fold	Homologous Superfamily
A, B, C, D	IPR002547	tRNA-binding domain	Domain
A, B, C, D	IPR037154	YtpR-like superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.