3BKD

High resolution Crystal structure of Transmembrane domain of M2 protein

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Membrane Protein Annotation: MemProtMD
Protein Modification Annotation

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
B	d3bkdb1	Peptides	Transmembrane helical fragments	Transmembrane helical fragments	Transmembrane helical fragments	Matrix protein M2 transmembrane peptide	( ) [TaxId: ], (Influenza A virus ) [TaxId: 97348 ],	SCOPe (2.08)
A	d3bkda1	Peptides	Transmembrane helical fragments	Transmembrane helical fragments	Transmembrane helical fragments	Matrix protein M2 transmembrane peptide	( ) [TaxId: ], (Influenza A virus ) [TaxId: 97348 ],	SCOPe (2.08)
C	d3bkdc1	Peptides	Transmembrane helical fragments	Transmembrane helical fragments	Transmembrane helical fragments	Matrix protein M2 transmembrane peptide	( ) [TaxId: ], (Influenza A virus ) [TaxId: 97348 ],	SCOPe (2.08)
D	d3bkdd1	Peptides	Transmembrane helical fragments	Transmembrane helical fragments	Transmembrane helical fragments	Matrix protein M2 transmembrane peptide	( ) [TaxId: ], (Influenza A virus ) [TaxId: 97348 ],	SCOPe (2.08)
E	d3bkde1	Peptides	Transmembrane helical fragments	Transmembrane helical fragments	Transmembrane helical fragments	Matrix protein M2 transmembrane peptide	( ) [TaxId: ], (Influenza A virus ) [TaxId: 97348 ],	SCOPe (2.08)
F	d3bkdf1	Peptides	Transmembrane helical fragments	Transmembrane helical fragments	Transmembrane helical fragments	Matrix protein M2 transmembrane peptide	( ) [TaxId: ], (Influenza A virus ) [TaxId: 97348 ],	SCOPe (2.08)
G	d3bkdg1	Peptides	Transmembrane helical fragments	Transmembrane helical fragments	Transmembrane helical fragments	Matrix protein M2 transmembrane peptide	( ) [TaxId: ], (Influenza A virus ) [TaxId: 97348 ],	SCOPe (2.08)
H	d3bkdh1	Peptides	Transmembrane helical fragments	Transmembrane helical fragments	Transmembrane helical fragments	Matrix protein M2 transmembrane peptide	( ) [TaxId: ], (Influenza A virus ) [TaxId: 97348 ],	SCOPe (2.08)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F, G, H	PF00599	Influenza Matrix protein (M2) (Flu_M2)	Influenza Matrix protein (M2)	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F, G, H	Transmembrane Domain of Matrix protein M2	passive transmembrane transporter activity monoatomic ion channel activity channel activity monoatomic ion transmembrane transporter activity transporter activity transmembrane transporter activity monoatomic cation transmembrane transporter activity proton transmembrane transporter activity inorganic molecular entity transmembrane transporter activity inorganic cation transmembrane transporter activity	cellular component organization cellular component biogenesis cellular component assembly protein-containing complex organization protein complex oligomerization protein-containing complex assembly cellular process cellular component organization or biogenesis biological process involved in interspecies interaction between organisms suppression by virus of host autophagy modulation by virus of host autophagy modulation by symbiont of host process viral process modulation by virus of host process cellular component organization cellular component biogenesis cellular component assembly protein-containing complex organization protein complex oligomerization protein-containing complex assembly cellular process cellular component organization or biogenesis biological process involved in interspecies interaction between organisms suppression by virus of host autophagy modulation by virus of host autophagy modulation by symbiont of host process viral process modulation by virus of host process modulation of process of another organism biological process involved in interaction with host modulation by virus of host cellular process biological process involved in symbiotic interaction	membrane cellular anatomical entity host cell plasma membrane host cellular component host cell part host cell membrane virion component virion membrane

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F, G, H	IPR002089	Influenza virus matrix protein 2	Family

Membrane Protein Annotation: MemProtMD MemProtMD Database Homepage

Chains	External Link	Comment
A, B, C, D, E A, B, C, D, E, F, G, H	MemProtMD	Annotated as membrane protein by MemProtMD

Protein Modification Annotation

Modified Residue(s)
Chain	Residue(s)	Description
A, B, C, D, E A, B, C, D, E, F, G, H	MSE	Parent Component: MET
A, B, C, D, E A, B, C, D, E, F, G, H	NH2	RESID: AA0081 , AA0083 , AA0084 , AA0086 , AA0087 , AA0088 , AA0090 , AA0091 , AA0092 , AA0093 , AA0095 , AA0096 , AA0097 , AA0098 , AA0099 , AA0100 PSI-MOD : L-alanine amide MOD:00090 , L-asparagine amide MOD:00092 , L-aspartic acid 1-amide MOD:00093 , L-glutamine amide MOD:00095 , L-glutamic acid 1-amide MOD:00096 , glycine amide MOD:00097 , L-isoleucine amide MOD:00099 , L-leucine amide MOD:00100 , L-lysine amide MOD:00101 , L-methionine amide MOD:00102 , L-proline amide MOD:00104 , L-serine amide MOD:00105 , L-threonine amide MOD:00106 , L-tryptophan amide MOD:00107 , L-tyrosine amide MOD:00108 , L-valine amide MOD:00109

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.