3AK5

Hemoglobin protease (Hbp) passenger missing domain-2

External Resource: Annotation

Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF02395	e3ak5A4	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: FMN-binding split barrel	F: PF02395	ECOD (1.6)
A	PF02395	e3ak5A3	A: beta duplicates or obligate multimers	X: Single-stranded right-handed beta-helix	H: Pectin lyase-like (From Topology)	T: Pectin lyase-like	F: PF02395	ECOD (1.6)
B	PF02395	e3ak5B4	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: FMN-binding split barrel	F: PF02395	ECOD (1.6)
B	PF02395	e3ak5B3	A: beta duplicates or obligate multimers	X: Single-stranded right-handed beta-helix	H: Pectin lyase-like (From Topology)	T: Pectin lyase-like	F: PF02395	ECOD (1.6)
C	PF02395	e3ak5C4	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: FMN-binding split barrel	F: PF02395	ECOD (1.6)
C	PF02395	e3ak5C3	A: beta duplicates or obligate multimers	X: Single-stranded right-handed beta-helix	H: Pectin lyase-like (From Topology)	T: Pectin lyase-like	F: PF02395	ECOD (1.6)
D	PF02395	e3ak5D4	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: FMN-binding split barrel	F: PF02395	ECOD (1.6)
D	PF02395	e3ak5D3	A: beta duplicates or obligate multimers	X: Single-stranded right-handed beta-helix	H: Pectin lyase-like (From Topology)	T: Pectin lyase-like	F: PF02395	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.40.10.120	Mainly Beta	Beta Barrel	Thrombin, subunit H		CATH (4.3.0)
A	2.160.20.20	Mainly Beta	3 Solenoid	Pectate Lyase C-like		CATH (4.3.0)
B	2.40.10.120	Mainly Beta	Beta Barrel	Thrombin, subunit H		CATH (4.3.0)
B	2.160.20.20	Mainly Beta	3 Solenoid	Pectate Lyase C-like		CATH (4.3.0)
C	2.40.10.120	Mainly Beta	Beta Barrel	Thrombin, subunit H		CATH (4.3.0)
C	2.160.20.20	Mainly Beta	3 Solenoid	Pectate Lyase C-like		CATH (4.3.0)
D	2.40.10.120	Mainly Beta	Beta Barrel	Thrombin, subunit H		CATH (4.3.0)
D	2.160.20.20	Mainly Beta	3 Solenoid	Pectate Lyase C-like		CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF02395	Immunoglobulin A1 protease (Peptidase_S6)	Immunoglobulin A1 protease	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	Hemoglobin-binding protease hbp	peptidase activity catalytic activity, acting on a protein serine hydrolase activity serine-type peptidase activity hydrolase activity serine-type endopeptidase activity catalytic activity endopeptidase activity	organic substance metabolic process organonitrogen compound metabolic process proteolysis metabolic process primary metabolic process protein metabolic process macromolecule metabolic process	extracellular region cellular anatomical entity cell surface periplasmic space cell periphery cell outer membrane external encapsulating structure membrane cell envelope outer membrane

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D	IPR036709	Autotransporter beta-domain superfamily	Homologous Superfamily
A, B, C, D	IPR009003	Peptidase S1, PA clan	Homologous Superfamily
A, B, C, D	IPR005546	Autotransporter beta-domain	Domain
A, B, C, D	IPR000710	Peptidase S6, IgA endopeptidase	Family
A, B, C, D	IPR006315	Outer membrane autotransporter barrel domain	Domain
A, B, C, D	IPR012332	Autotransporter, pectate lyase C-like domain superfamily	Homologous Superfamily
A, B, C, D	IPR030396	Peptidase family S6 domain	Domain
A, B, C, D	IPR011050	Pectin lyase fold/virulence factor	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.