3A7O

The crystal structure of the coiled-coil domain of Saccharomyces cerevisiae Atg16

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	ATG16 helical segment-like	8090303	3002426	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	ATG16 helical segment-like	8090303	3002426	SCOP2B (2022-06-29)
C	SCOP2 Family	ATG16-like	8051034	4007169	SCOP2 (2022-06-29)
C	SCOP2 Superfamily	ATG16 helical segment-like	8090303	3002426	SCOP2 (2022-06-29)
D	SCOP2B Superfamily	ATG16 helical segment-like	8090303	3002426	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	ATG16 helical segment-like	8090303	3002426	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	ATG16 helical segment-like	8090303	3002426	SCOP2B (2022-06-29)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.20.5.170	Mainly Alpha	Up-down Bundle	Single alpha-helices involved in coiled-coils or other helix-helix interfaces		CATH (4.3.0)
B	1.20.5.170	Mainly Alpha	Up-down Bundle	Single alpha-helices involved in coiled-coils or other helix-helix interfaces		CATH (4.3.0)
F	1.20.5.170	Mainly Alpha	Up-down Bundle	Single alpha-helices involved in coiled-coils or other helix-helix interfaces		CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F	PF08614	Autophagy protein 16 (ATG16) (ATG16)	Autophagy protein 16 (ATG16)	-	Coiled-coil

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F	Autophagy protein 16	protein-macromolecule adaptor activity molecular adaptor activity identical protein binding protein binding binding	cellular catabolic process catabolic process macroautophagy cellular metabolic process autophagy cellular process metabolic process process utilizing autophagic mechanism cellular component disassembly cellular component organization organelle organization organelle disassembly cellular component organization or biogenesis autophagy of mitochondrion cellular catabolic process catabolic process macroautophagy cellular metabolic process autophagy cellular process metabolic process process utilizing autophagic mechanism cellular component disassembly cellular component organization organelle organization organelle disassembly cellular component organization or biogenesis autophagy of mitochondrion mitochondrion organization protein localization establishment of protein localization cellular localization nitrogen compound transport transport protein targeting establishment of protein localization to vacuole cytoplasm to vacuole targeting by the Cvt pathway localization cellular macromolecule localization establishment of localization in cell protein targeting to vacuole organic substance transport protein localization to vacuole intracellular transport establishment of localization establishment of protein localization to organelle protein transport macromolecule localization protein localization to organelle vacuolar transport intracellular protein transport autophagosome assembly organelle assembly vacuole organization autophagosome organization cellular component biogenesis cellular component assembly piecemeal microautophagy of the nucleus microautophagy nucleophagy C-terminal protein amino acid modification organonitrogen compound metabolic process cellular biosynthetic process lipoprotein biosynthetic process lipoprotein metabolic process organonitrogen compound biosynthetic process primary metabolic process macromolecule biosynthetic process protein lipidation organic substance metabolic process biosynthetic process macromolecule modification organic substance biosynthetic process protein metabolic process macromolecule metabolic process protein modification process post-translational protein modification C-terminal protein lipidation	protein-containing complex intracellular anatomical structure catalytic complex Atg12-Atg5-Atg16 complex transferase complex cytoplasm cellular anatomical entity organelle membrane contact site organelle vacuole-isolation membrane contact site phagophore cytosol phagophore assembly site membrane membrane protein-containing complex intracellular anatomical structure catalytic complex Atg12-Atg5-Atg16 complex transferase complex cytoplasm cellular anatomical entity organelle membrane contact site organelle vacuole-isolation membrane contact site phagophore cytosol phagophore assembly site membrane membrane phagophore assembly site membrane-bounded organelle intracellular organelle nucleus intracellular membrane-bounded organelle

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F	IPR013923	Autophagy-related protein 16 domain	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.