2YY3

Crystal Structure of translation elongation factor EF-1 beta from Pyrococcus horikoshii

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	eEF-1beta-like	8063607	4001327	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	eEF-1beta-like	8063608	3001297	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	eEF-1beta-like	8063608	3001297	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	eEF-1beta-like	8063608	3001297	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF00736	e2yy3A1	A: a+b two layers	X: Alpha-beta plaits	H: eEF-1beta-like (From Topology)	T: eEF-1beta-like	F: PF00736	ECOD (1.6)
B	PF00736	e2yy3B1	A: a+b two layers	X: Alpha-beta plaits	H: eEF-1beta-like (From Topology)	T: eEF-1beta-like	F: PF00736	ECOD (1.6)
C	PF00736	e2yy3C1	A: a+b two layers	X: Alpha-beta plaits	H: eEF-1beta-like (From Topology)	T: eEF-1beta-like	F: PF00736	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.30.70.60	Alpha Beta	2-Layer Sandwich	Alpha-Beta Plaits	Ribosomal protein S6/Translation elongation factor EF1B	CATH (4.3.0)
B	3.30.70.60	Alpha Beta	2-Layer Sandwich	Alpha-Beta Plaits	Ribosomal protein S6/Translation elongation factor EF1B	CATH (4.3.0)
C	3.30.70.60	Alpha Beta	2-Layer Sandwich	Alpha-Beta Plaits	Ribosomal protein S6/Translation elongation factor EF1B	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C	PF00736	EF-1 guanine nucleotide exchange domain (EF1_GNE)	EF-1 guanine nucleotide exchange domain	This family is the guanine nucleotide exchange domain of EF-1 beta and EF-1 delta chains.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C	Elongation factor 1-beta	translation regulator activity binding organic cyclic compound binding translation regulator activity, nucleic acid binding translation elongation factor activity nucleic acid binding translation factor activity, RNA binding	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C	IPR004542	Translation elongation factor EF1B, beta chain, archaeal	Family
A, B, C	IPR036219	Translation elongation factor eEF-1beta-like superfamily	Homologous Superfamily
A, B, C	IPR014038	Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain	Domain
A, B, C	IPR014717	Translation elongation factor EF1B/small ribosomal subunit protein bS6	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.