Annotations: 2YXL

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	F_UNCLASSIFIED	e2yxlA2	A: alpha complex topology	X: NusB-like (From Topology)	H: NusB-like (From Topology)	T: NusB-like	F: F_UNCLASSIFIED	ECOD (1.6)
A	PF22458	e2yxlA3	A: a+b two layers	X: Alpha-beta plaits	H: NOL1/NOP2/sun N-terminal ferredoxin-like domain (From Topology)	T: NOL1/NOP2/sun N-terminal ferredoxin-like domain	F: PF22458	ECOD (1.6)
A	PF01189	e2yxlA1	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: S-adenosyl-L-methionine-dependent methyltransferases	F: PF01189	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.10.940.10	Mainly Alpha	Orthogonal Bundle	N-utilizing Substance Protein B Homolog	Chain A	CATH (4.3.0)
A	1.10.287.730	Mainly Alpha	Orthogonal Bundle	Helix Hairpins	Helix hairpin bin	CATH (4.3.0)
A	3.30.70.1170	Alpha Beta	2-Layer Sandwich	Alpha-Beta Plaits	Sun protein	CATH (4.3.0)
A	3.40.50.150	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Vaccinia Virus protein VP39	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF17125	N-terminal domain of 16S rRNA methyltransferase RsmF (Methyltr_RsmF_N)	N-terminal domain of 16S rRNA methyltransferase RsmF	This is the N-terminal domain of the RsmF methyl transferase. RsmF is a multi-site-specific methyltransferase that is responsible for the synthesis of three modifications on cytidines in 16S ribosomal RNA. The N-terminus is critical for stabilising t ...	This is the N-terminal domain of the RsmF methyl transferase. RsmF is a multi-site-specific methyltransferase that is responsible for the synthesis of three modifications on cytidines in 16S ribosomal RNA. The N-terminus is critical for stabilising the catalytic core of the enzyme [1].	Domain
A	PF01189	16S rRNA methyltransferase RsmB/F (Methyltr_RsmB-F)	16S rRNA methyltransferase RsmB/F	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	450aa long hypothetical fmu protein	RNA methyltransferase activity catalytic activity, acting on RNA transferase activity, transferring one-carbon groups catalytic activity, acting on a nucleic acid transferase activity methyltransferase activity catalytic activity S-adenosylmethionine-dependent methyltransferase activity RNA binding binding organic cyclic compound binding nucleic acid binding	RNA metabolic process primary metabolic process nucleic acid metabolic process macromolecule methylation nucleobase-containing compound metabolic process organic cyclic compound metabolic process RNA modification organic substance metabolic process methylation macromolecule modification metabolic process macromolecule metabolic process RNA methylation cellular biosynthetic process RNA metabolic process primary metabolic process nucleic acid metabolic process macromolecule methylation nucleobase-containing compound metabolic process organic cyclic compound metabolic process RNA modification organic substance metabolic process methylation macromolecule modification metabolic process macromolecule metabolic process RNA methylation cellular biosynthetic process cellular metabolic process gene expression macromolecule biosynthetic process biosynthetic process organic substance biosynthetic process cellular process RNA processing	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR031341	Ribosomal RNA small subunit methyltransferase F, N-terminal	Domain
A	IPR035926	NusB-like superfamily	Homologous Superfamily
A	IPR001678	SAM-dependent methyltransferase RsmB-F/NOP2-type domain	Domain
A	IPR029063	S-adenosyl-L-methionine-dependent methyltransferase superfamily	Homologous Superfamily
A	IPR049560	SAM-dependent methyltransferase RsmB-F/NOP2-type, catalytic core	Domain
A	IPR023267	RNA (C5-cytosine) methyltransferase	Family
A	IPR011023	Nop2p	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.