2Y3P
Crystal structure of N-terminal domain of GyrA with the antibiotic simocyclinone D8
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | d2y3pa_ | Multi-domain proteins (alpha and beta) | Type II DNA topoisomerase C-terminal domain-like | Type II DNA topoisomerase C-terminal domain-like | Type II DNA topoisomerase C-terminal domain-like | automated matches | (Escherichia coli ) [TaxId: 562 ], | SCOPe (2.08) |
B | d2y3pb_ | Multi-domain proteins (alpha and beta) | Type II DNA topoisomerase C-terminal domain-like | Type II DNA topoisomerase C-terminal domain-like | Type II DNA topoisomerase C-terminal domain-like | automated matches | (Escherichia coli ) [TaxId: 562 ], | SCOPe (2.08) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | PF00521 | e2y3pA1 | A: alpha arrays | X: HTH | H: HTH | T: winged | F: PF00521 | ECOD (1.6) |
A | PF00521 | e2y3pA2 | A: alpha bundles | X: alpha-helical domain in type II DNA topoisomerase (From Topology) | H: alpha-helical domain in type II DNA topoisomerase (From Topology) | T: alpha-helical domain in type II DNA topoisomerase | F: PF00521 | ECOD (1.6) |
A | PF00521 | e2y3pA3 | A: a+b two layers | X: a+b domain in type II DNA topoisomerase (From Topology) | H: a+b domain in type II DNA topoisomerase (From Topology) | T: a+b domain in type II DNA topoisomerase | F: PF00521 | ECOD (1.6) |
B | PF00521 | e2y3pB1 | A: alpha arrays | X: HTH | H: HTH | T: winged | F: PF00521 | ECOD (1.6) |
B | PF00521 | e2y3pB2 | A: alpha bundles | X: alpha-helical domain in type II DNA topoisomerase (From Topology) | H: alpha-helical domain in type II DNA topoisomerase (From Topology) | T: alpha-helical domain in type II DNA topoisomerase | F: PF00521 | ECOD (1.6) |
B | PF00521 | e2y3pB3 | A: a+b two layers | X: a+b domain in type II DNA topoisomerase (From Topology) | H: a+b domain in type II DNA topoisomerase (From Topology) | T: a+b domain in type II DNA topoisomerase | F: PF00521 | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 3.90.199.10 | Alpha Beta | Alpha-Beta Complex | Topoisomerase II | domain 5 | CATH (4.3.0) |
A | 3.30.1360.40 | Alpha Beta | 2-Layer Sandwich | Gyrase A | domain 2 | CATH (4.3.0) |
A | 1.10.268.10 | Mainly Alpha | Orthogonal Bundle | Topoisomerase | domain 3 | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF00521 | DNA gyrase/topoisomerase IV, subunit A (DNA_topoisoIV) | DNA gyrase/topoisomerase IV, subunit A | - | Family |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR035516 | DNA gyrase/topoisomerase IV, subunit A, C-terminal | Homologous Superfamily | |
IPR013760 | DNA topoisomerase, type IIA-like domain superfamily | Homologous Superfamily | |
IPR013757 | DNA topoisomerase, type IIA, alpha-helical domain superfamily | Homologous Superfamily | |
IPR013758 | DNA topoisomerase, type IIA, domain A, alpha-beta | Homologous Superfamily | |
IPR005743 | DNA gyrase, subunit A | Family | |
IPR006691 | DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat | Repeat | |
IPR002205 | DNA topoisomerase, type IIA, domain A | Domain |