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X-ray structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXR, Rv2870c, from Mycobacterium tuberculosis, in complex with a 3,4- dichlorophenyl-substituted FR900098 analogue and manganese. External Resource: Annotation Chains Family Name Domain Identifier Architecture Possible Homology Homology Topology Family Provenance Source (Version) A PF13288 e2y1gA3 A: alpha superhelices X: 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C (From Topology) H: 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C (From Topology) T: 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C F: PF13288 ECOD (1.6) A PF08436 e2y1gA1 A: a+b two layers X: FwdE/GAPDH domain-like H: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain (From Topology) T: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain F: PF08436 ECOD (1.6) A PF02670 e2y1gA2 A: a/b three-layered sandwiches X: Rossmann-like H: Rossmann-related T: NAD(P)-binding Rossmann-fold domains F: PF02670 ECOD (1.6) B PF13288 e2y1gB2 A: alpha superhelices X: 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C (From Topology) H: 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C (From Topology) T: 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C F: PF13288 ECOD (1.6) B PF08436 e2y1gB3 A: a+b two layers X: FwdE/GAPDH domain-like H: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain (From Topology) T: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain F: PF08436 ECOD (1.6) B PF02670 e2y1gB1 A: a/b three-layered sandwiches X: Rossmann-like H: Rossmann-related T: NAD(P)-binding Rossmann-fold domains F: PF02670 ECOD (1.6)
