2XWZ

STRUCTURE OF THE RECOMBINANT NATIVE NITRITE REDUCTASE FROM ALCALIGENES XYLOSOXIDANS complexed with nitrite

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d2xwza2	All beta proteins	Cupredoxin-like	Cupredoxins	Multidomain cupredoxins	Nitrite reductase, NIR, C-terminal domain	(Achromobacter xylosoxidans ) [TaxId: 85698 ],	SCOPe (2.08)
A	d2xwza1	All beta proteins	Cupredoxin-like	Cupredoxins	Multidomain cupredoxins	Nitrite reductase, NIR, N-terminal domain	(Achromobacter xylosoxidans ) [TaxId: 85698 ],	SCOPe (2.08)
B	d2xwzb2	All beta proteins	Cupredoxin-like	Cupredoxins	Multidomain cupredoxins	Nitrite reductase, NIR, C-terminal domain	(Achromobacter xylosoxidans ) [TaxId: 85698 ],	SCOPe (2.08)
B	d2xwzb1	All beta proteins	Cupredoxin-like	Cupredoxins	Multidomain cupredoxins	Nitrite reductase, NIR, N-terminal domain	(Achromobacter xylosoxidans ) [TaxId: 85698 ],	SCOPe (2.08)
C	d2xwzc2	All beta proteins	Cupredoxin-like	Cupredoxins	Multidomain cupredoxins	Nitrite reductase, NIR, C-terminal domain	(Achromobacter xylosoxidans ) [TaxId: 85698 ],	SCOPe (2.08)
C	d2xwzc1	All beta proteins	Cupredoxin-like	Cupredoxins	Multidomain cupredoxins	Nitrite reductase, NIR, N-terminal domain	(Achromobacter xylosoxidans ) [TaxId: 85698 ],	SCOPe (2.08)
D	d2xwzd2	All beta proteins	Cupredoxin-like	Cupredoxins	Multidomain cupredoxins	Nitrite reductase, NIR, C-terminal domain	(Achromobacter xylosoxidans ) [TaxId: 85698 ],	SCOPe (2.08)
D	d2xwzd1	All beta proteins	Cupredoxin-like	Cupredoxins	Multidomain cupredoxins	Nitrite reductase, NIR, N-terminal domain	(Achromobacter xylosoxidans ) [TaxId: 85698 ],	SCOPe (2.08)
E	d2xwze2	All beta proteins	Cupredoxin-like	Cupredoxins	Multidomain cupredoxins	Nitrite reductase, NIR, C-terminal domain	(Achromobacter xylosoxidans ) [TaxId: 85698 ],	SCOPe (2.08)
E	d2xwze1	All beta proteins	Cupredoxin-like	Cupredoxins	Multidomain cupredoxins	Nitrite reductase, NIR, N-terminal domain	(Achromobacter xylosoxidans ) [TaxId: 85698 ],	SCOPe (2.08)
F	d2xwzf2	All beta proteins	Cupredoxin-like	Cupredoxins	Multidomain cupredoxins	Nitrite reductase, NIR, C-terminal domain	(Achromobacter xylosoxidans ) [TaxId: 85698 ],	SCOPe (2.08)
F	d2xwzf1	All beta proteins	Cupredoxin-like	Cupredoxins	Multidomain cupredoxins	Nitrite reductase, NIR, N-terminal domain	(Achromobacter xylosoxidans ) [TaxId: 85698 ],	SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Cu-oxidase_2_2	e2xwzA2	A: beta sandwiches	X: Cupredoxin-like	H: Cupredoxin-related (From Topology)	T: Cupredoxin-related	F: Cu-oxidase_2_2	ECOD (1.6)
A	Cu-oxidase_3_1	e2xwzA1	A: beta sandwiches	X: Cupredoxin-like	H: Cupredoxin-related (From Topology)	T: Cupredoxin-related	F: Cu-oxidase_3_1	ECOD (1.6)
B	Cu-oxidase_2_2	e2xwzB2	A: beta sandwiches	X: Cupredoxin-like	H: Cupredoxin-related (From Topology)	T: Cupredoxin-related	F: Cu-oxidase_2_2	ECOD (1.6)
B	Cu-oxidase_3_1	e2xwzB1	A: beta sandwiches	X: Cupredoxin-like	H: Cupredoxin-related (From Topology)	T: Cupredoxin-related	F: Cu-oxidase_3_1	ECOD (1.6)
C	Cu-oxidase_2_2	e2xwzC2	A: beta sandwiches	X: Cupredoxin-like	H: Cupredoxin-related (From Topology)	T: Cupredoxin-related	F: Cu-oxidase_2_2	ECOD (1.6)
C	Cu-oxidase_3_1	e2xwzC1	A: beta sandwiches	X: Cupredoxin-like	H: Cupredoxin-related (From Topology)	T: Cupredoxin-related	F: Cu-oxidase_3_1	ECOD (1.6)
D	Cu-oxidase_2_2	e2xwzD2	A: beta sandwiches	X: Cupredoxin-like	H: Cupredoxin-related (From Topology)	T: Cupredoxin-related	F: Cu-oxidase_2_2	ECOD (1.6)
D	Cu-oxidase_3_1	e2xwzD1	A: beta sandwiches	X: Cupredoxin-like	H: Cupredoxin-related (From Topology)	T: Cupredoxin-related	F: Cu-oxidase_3_1	ECOD (1.6)
E	Cu-oxidase_2_2	e2xwzE2	A: beta sandwiches	X: Cupredoxin-like	H: Cupredoxin-related (From Topology)	T: Cupredoxin-related	F: Cu-oxidase_2_2	ECOD (1.6)
E	Cu-oxidase_3_1	e2xwzE1	A: beta sandwiches	X: Cupredoxin-like	H: Cupredoxin-related (From Topology)	T: Cupredoxin-related	F: Cu-oxidase_3_1	ECOD (1.6)
F	Cu-oxidase_2_2	e2xwzF2	A: beta sandwiches	X: Cupredoxin-like	H: Cupredoxin-related (From Topology)	T: Cupredoxin-related	F: Cu-oxidase_2_2	ECOD (1.6)
F	Cu-oxidase_3_1	e2xwzF1	A: beta sandwiches	X: Cupredoxin-like	H: Cupredoxin-related (From Topology)	T: Cupredoxin-related	F: Cu-oxidase_3_1	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.60.40.420	Mainly Beta	Sandwich	Immunoglobulin-like	Cupredoxins - blue copper proteins	CATH (4.3.0)
B	2.60.40.420	Mainly Beta	Sandwich	Immunoglobulin-like	Cupredoxins - blue copper proteins	CATH (4.3.0)
C	2.60.40.420	Mainly Beta	Sandwich	Immunoglobulin-like	Cupredoxins - blue copper proteins	CATH (4.3.0)
D	2.60.40.420	Mainly Beta	Sandwich	Immunoglobulin-like	Cupredoxins - blue copper proteins	CATH (4.3.0)
E	2.60.40.420	Mainly Beta	Sandwich	Immunoglobulin-like	Cupredoxins - blue copper proteins	CATH (4.3.0)
F	2.60.40.420	Mainly Beta	Sandwich	Immunoglobulin-like	Cupredoxins - blue copper proteins	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F	PF00394	Multicopper oxidase (Cu-oxidase)	Multicopper oxidase	Many of the proteins in this family contain multiple similar copies of this plastocyanin-like domain.	Domain
A, B, C, D, E A, B, C, D, E, F	PF07732	Multicopper oxidase (Cu-oxidase_3)	Multicopper oxidase	This entry contains many divergent copper oxidase-like domains that are not recognised by the Pfam:PF00394 model.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F	DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE	cation binding transition metal ion binding copper ion binding ion binding binding metal ion binding small molecule binding oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor oxidoreductase activity oxidoreductase activity, acting on other nitrogenous compounds as donors nitrite reductase (NO-forming) activity nitrite reductase activity catalytic activity	nitrogen cycle metabolic process denitrification pathway metabolic process nitrate assimilation oxoacid metabolic process cellular metabolic process organic acid metabolic process reactive nitrogen species metabolic process organic substance metabolic process small molecule metabolic process cellular process nitrate metabolic process	periplasmic space cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F	IPR008972	Cupredoxin	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F	IPR001117	Multicopper oxidase, second cupredoxin domain	Domain
A, B, C, D, E A, B, C, D, E, F	IPR045087	Multicopper oxidase	Family
A, B, C, D, E A, B, C, D, E, F	IPR001287	Nitrite reductase, copper-type	Family
A, B, C, D, E A, B, C, D, E, F	IPR011707	Multicopper oxidase-like, N-terminal	Domain

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.