2XU0

Crystal structure of the NTS-DBL1(alpha-1) domain of the Plasmodium falciparum membrane protein 1 (PfEMP1) from the varO strain.

External Resource: Annotation


Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
APF05424,PF15447e2xu0A1 A: alpha bundlesX: Duffy-binding-like domain, N-terminal subdomain (From Topology)H: Duffy-binding-like domain, N-terminal subdomain (From Topology)T: Duffy-binding-like domain, N-terminal subdomainF: PF05424,PF15447ECOD (1.6)
APF22672e2xu0A2 A: alpha bundlesX: Duffy-binding-like domain, C-terminal subdomain (From Topology)H: Duffy-binding-like domain, C-terminal subdomain (From Topology)T: Duffy-binding-like domain, C-terminal subdomainF: PF22672ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
PF05424Duffy binding domain (Duffy_binding)Duffy binding domain- Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
ERYTHROCYTE MEMBRANE PROTEIN 1 -

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
IPR008602Duffy-antigen binding domainDomain
IPR004258Duffy-binding-like domainDomain
IPR018247EF-Hand 1, calcium-binding siteBinding Site
IPR042202Duffy-antigen binding superfamilyHomologous Superfamily
IPR029211Plasmodium falciparum erythrocyte membrane protein 1, acidic terminal segmentDomain
IPR029210Plasmodium falciparum erythrocyte membrane protein-1, N-terminal segmentDomain
IPR041480Cysteine-rich interdomain region 1 gammaDomain

Membrane Protein Annotation: OPM OPM Database Homepage

ChainsExternal LinkTypeClassSuperfamilyFamily
OPMMonotopic/peripheralAll alpha monotopic/peripheralDBL (Duffy-binding like)PfEMP1 (Plasmodium falciparum erythrocyte membrane protein)