2X31

Modelling of the complex between subunits BchI and BchD of magnesium chelatase based on single-particle cryo-EM reconstruction at 7.5 ang

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
G	SCOP2B Superfamily	RecA-like P-loop NTPases	8032692	3002019	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	RecA-like P-loop NTPases	8032692	3002019	SCOP2B (2022-06-29)
I	SCOP2B Superfamily	RecA-like P-loop NTPases	8032692	3002019	SCOP2B (2022-06-29)
J	SCOP2B Superfamily	RecA-like P-loop NTPases	8032692	3002019	SCOP2B (2022-06-29)
K	SCOP2B Superfamily	RecA-like P-loop NTPases	8032692	3002019	SCOP2B (2022-06-29)
L	SCOP2B Superfamily	RecA-like P-loop NTPases	8032692	3002019	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
G	MoxR	e2x31G1	A: alpha arrays	X: Histone-like	H: Histone-related	T: AAA+ ATPase lid domain	F: MoxR	ECOD (1.6)
G	Sigma54_activat	e2x31G2	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: Sigma54_activat	ECOD (1.6)
H	MoxR	e2x31H2	A: alpha arrays	X: Histone-like	H: Histone-related	T: AAA+ ATPase lid domain	F: MoxR	ECOD (1.6)
H	Sigma54_activat	e2x31H1	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: Sigma54_activat	ECOD (1.6)
I	MoxR	e2x31I2	A: alpha arrays	X: Histone-like	H: Histone-related	T: AAA+ ATPase lid domain	F: MoxR	ECOD (1.6)
I	Sigma54_activat	e2x31I1	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: Sigma54_activat	ECOD (1.6)
J	MoxR	e2x31J2	A: alpha arrays	X: Histone-like	H: Histone-related	T: AAA+ ATPase lid domain	F: MoxR	ECOD (1.6)
J	Sigma54_activat	e2x31J1	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: Sigma54_activat	ECOD (1.6)
K	MoxR	e2x31K2	A: alpha arrays	X: Histone-like	H: Histone-related	T: AAA+ ATPase lid domain	F: MoxR	ECOD (1.6)
K	Sigma54_activat	e2x31K1	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: Sigma54_activat	ECOD (1.6)
L	MoxR	e2x31L2	A: alpha arrays	X: Histone-like	H: Histone-related	T: AAA+ ATPase lid domain	F: MoxR	ECOD (1.6)
L	Sigma54_activat	e2x31L1	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: Sigma54_activat	ECOD (1.6)
A	VWA	e2x31A1	A: a/b three-layered sandwiches	X: HAD domain-like	H: HAD domain-related	T: vWA-like	F: VWA	ECOD (1.6)
B	VWA	e2x31B1	A: a/b three-layered sandwiches	X: HAD domain-like	H: HAD domain-related	T: vWA-like	F: VWA	ECOD (1.6)
C	VWA	e2x31C1	A: a/b three-layered sandwiches	X: HAD domain-like	H: HAD domain-related	T: vWA-like	F: VWA	ECOD (1.6)
D	VWA	e2x31D1	A: a/b three-layered sandwiches	X: HAD domain-like	H: HAD domain-related	T: vWA-like	F: VWA	ECOD (1.6)
E	VWA	e2x31E1	A: a/b three-layered sandwiches	X: HAD domain-like	H: HAD domain-related	T: vWA-like	F: VWA	ECOD (1.6)
F	VWA	e2x31F1	A: a/b three-layered sandwiches	X: HAD domain-like	H: HAD domain-related	T: vWA-like	F: VWA	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
G, H, I, J, K G, H, I, J, K, L	PF17863	AAA lid domain (AAA_lid_2)	AAA lid domain	This entry represents the alpha helical AAA+ lid domain that is found to the C-terminus of AAA domains.	Domain
G, H, I, J, K G, H, I, J, K, L	PF01078	Magnesium chelatase, subunit ChlI (Mg_chelatase)	Magnesium chelatase, subunit ChlI	Magnesium-chelatase is a three-component enzyme that catalyses the insertion of Mg2+ into protoporphyrin IX. This is the first unique step in the synthesis of (bacterio)chlorophyll. Due to this, it is thought that Mg-chelatase has an important ro ...	Magnesium-chelatase is a three-component enzyme that catalyses the insertion of Mg2+ into protoporphyrin IX. This is the first unique step in the synthesis of (bacterio)chlorophyll. Due to this, it is thought that Mg-chelatase has an important role in channelling inter- mediates into the (bacterio)chlorophyll branch in response to conditions suitable for photosynthetic growth. ChlI and BchD have molecular weight between 38-42 kDa.	Domain
A, B, C, D, E A, B, C, D, E, F	PF13519	von Willebrand factor type A domain (VWA_2)	von Willebrand factor type A domain	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
G, H, I, J, K G, H, I, J, K, L	MAGNESIUM-CHELATASE 38 KDA SUBUNIT	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding pyrophosphatase activity ATP hydrolysis activity ribonucleoside triphosphate phosphatase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides hydrolase activity hydrolase activity, acting on acid anhydrides catalytic activity ATP-dependent activity ligase activity, forming nitrogen-metal bonds ligase activity, forming nitrogen-metal bonds, forming coordination complexes magnesium chelatase activity ligase activity	photosynthesis cellular metabolic process metabolic process cellular process pigment metabolic process organonitrogen compound metabolic process porphyrin-containing compound biosynthetic process tetrapyrrole metabolic process chlorophyll metabolic process organonitrogen compound biosynthetic process bacteriochlorophyll metabolic process pigment biosynthetic process bacteriochlorophyll biosynthetic process organic cyclic compound metabolic process photosynthesis cellular metabolic process metabolic process cellular process pigment metabolic process organonitrogen compound metabolic process porphyrin-containing compound biosynthetic process tetrapyrrole metabolic process chlorophyll metabolic process organonitrogen compound biosynthetic process bacteriochlorophyll metabolic process pigment biosynthetic process bacteriochlorophyll biosynthetic process organic cyclic compound metabolic process organic substance metabolic process tetrapyrrole biosynthetic process biosynthetic process organic cyclic compound biosynthetic process organic substance biosynthetic process porphyrin-containing compound metabolic process chlorophyll biosynthetic process	-
A, B, C, D, E A, B, C, D, E, F	MAGNESIUM-CHELATASE 60 KDA SUBUNIT	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding ligase activity, forming nitrogen-metal bonds ligase activity, forming nitrogen-metal bonds, forming coordination complexes magnesium chelatase activity catalytic activity ligase activity	photosynthesis cellular metabolic process metabolic process cellular process pigment metabolic process organonitrogen compound metabolic process porphyrin-containing compound biosynthetic process tetrapyrrole metabolic process chlorophyll metabolic process organonitrogen compound biosynthetic process bacteriochlorophyll metabolic process pigment biosynthetic process bacteriochlorophyll biosynthetic process organic cyclic compound metabolic process photosynthesis cellular metabolic process metabolic process cellular process pigment metabolic process organonitrogen compound metabolic process porphyrin-containing compound biosynthetic process tetrapyrrole metabolic process chlorophyll metabolic process organonitrogen compound biosynthetic process bacteriochlorophyll metabolic process pigment biosynthetic process bacteriochlorophyll biosynthetic process organic cyclic compound metabolic process organic substance metabolic process tetrapyrrole biosynthetic process biosynthetic process organic cyclic compound biosynthetic process organic substance biosynthetic process porphyrin-containing compound metabolic process chlorophyll biosynthetic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
G, H, I, J, K G, H, I, J, K, L	IPR011775	Magnesium chelatase, ATPase subunit I	Family
G, H, I, J, K G, H, I, J, K, L	IPR045006	Magnesium-chelatase subunit ChlI-like	Family
G, H, I, J, K G, H, I, J, K, L	IPR041628	ChlI/MoxR, AAA lid domain	Domain
G, H, I, J, K G, H, I, J, K, L	IPR003593	AAA+ ATPase domain	Domain
G, H, I, J, K G, H, I, J, K, L	IPR000523	Magnesium chelatase ChlI-like, catalytic domain	Domain
G, H, I, J, K G, H, I, J, K, L	IPR027417	P-loop containing nucleoside triphosphate hydrolase	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F	IPR041628	ChlI/MoxR, AAA lid domain	Domain
A, B, C, D, E A, B, C, D, E, F	IPR002035	von Willebrand factor, type A	Domain
A, B, C, D, E A, B, C, D, E, F	IPR036465	von Willebrand factor A-like domain superfamily	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F	IPR041702	Magnesium-chelatase BchD/ChlD, VWA domain	Domain
A, B, C, D, E A, B, C, D, E, F	IPR011776	Magnesium chelatase, ATPase subunit D	Family
A, B, C, D, E A, B, C, D, E, F	IPR027417	P-loop containing nucleoside triphosphate hydrolase	Homologous Superfamily

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.