Annotations: 2V9U

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
B	PF09203	e2v9uB1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Leukocidin-like (From Topology)	T: Leukocidin-like	F: PF09203	ECOD (1.6)
C	PF09203	e2v9uC1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Leukocidin-like (From Topology)	T: Leukocidin-like	F: PF09203	ECOD (1.6)
D	PF09203	e2v9uD1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Leukocidin-like (From Topology)	T: Leukocidin-like	F: PF09203	ECOD (1.6)
E	PF09203	e2v9uE1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Leukocidin-like (From Topology)	T: Leukocidin-like	F: PF09203	ECOD (1.6)
A	PF09203	e2v9uA1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Leukocidin-like (From Topology)	T: Leukocidin-like	F: PF09203	ECOD (1.6)
F	PF09203	e2v9uF1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Leukocidin-like (From Topology)	T: Leukocidin-like	F: PF09203	ECOD (1.6)
G	PF09203	e2v9uG1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Leukocidin-like (From Topology)	T: Leukocidin-like	F: PF09203	ECOD (1.6)
H	PF09203	e2v9uH1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Leukocidin-like (From Topology)	T: Leukocidin-like	F: PF09203	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
B	2.60.40.1650	Mainly Beta	Sandwich	Immunoglobulin-like	Porin MspA (Ig-like beta-sandwich domain)	CATH (4.3.0)
C	2.60.40.1650	Mainly Beta	Sandwich	Immunoglobulin-like	Porin MspA (Ig-like beta-sandwich domain)	CATH (4.3.0)
D	2.60.40.1650	Mainly Beta	Sandwich	Immunoglobulin-like	Porin MspA (Ig-like beta-sandwich domain)	CATH (4.3.0)
E	2.60.40.1650	Mainly Beta	Sandwich	Immunoglobulin-like	Porin MspA (Ig-like beta-sandwich domain)	CATH (4.3.0)
A	2.60.40.1650	Mainly Beta	Sandwich	Immunoglobulin-like	Porin MspA (Ig-like beta-sandwich domain)	CATH (4.3.0)
F	2.60.40.1650	Mainly Beta	Sandwich	Immunoglobulin-like	Porin MspA (Ig-like beta-sandwich domain)	CATH (4.3.0)
G	2.60.40.1650	Mainly Beta	Sandwich	Immunoglobulin-like	Porin MspA (Ig-like beta-sandwich domain)	CATH (4.3.0)
H	2.60.40.1650	Mainly Beta	Sandwich	Immunoglobulin-like	Porin MspA (Ig-like beta-sandwich domain)	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F, G, H	PF09203	MspA (MspA)	MspA	MspA is a membrane porin produced by Mycobacteria, allowing hydrophilic nutrients to enter the bacterium. The protein forms a tightly interconnected octamer with eightfold rotation symmetry that resembles a goblet and contains a central channel. Each ...	MspA is a membrane porin produced by Mycobacteria, allowing hydrophilic nutrients to enter the bacterium. The protein forms a tightly interconnected octamer with eightfold rotation symmetry that resembles a goblet and contains a central channel. Each subunit fold contains a beta-sandwich of Ig-like topology and a beta-ribbon arm that forms an oligomeric transmembrane barrel [1].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F, G, H	MSPA	wide pore channel activity passive transmembrane transporter activity channel activity porin activity transporter activity transmembrane transporter activity	localization transport iron ion transport transition metal ion transport monoatomic ion transport monoatomic cation transport establishment of localization metal ion transport	extracellular region cellular anatomical entity protein-containing complex membrane pore complex membrane protein complex cell periphery cell outer membrane external encapsulating structure cell envelope outer membrane

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F, G, H	IPR036435	Leukocidin/porin MspA superfamily	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G, H	IPR015286	Porin family, mycobacterial-type	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.