2V7Q

The structure of F1-ATPase inhibited by I1-60HIS, a monomeric form of the inhibitor protein, IF1.

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d2v7qa3	All alpha proteins	Left-handed superhelix	C-terminal domain of alpha and beta (or A/B) subunits of rotary ATPases	automated matches	automated matches	(Bos taurus ) [TaxId: 9913 ],	SCOPe (2.08)
A	d2v7qa1	All beta proteins	Domain of alpha and beta subunits of F1 ATP synthase-like	N-terminal domain of alpha and beta (or A/B) subunits of rotary ATPases	automated matches	automated matches	(Bos taurus ) [TaxId: 9913 ],	SCOPe (2.08)
A	d2v7qa2	Alpha and beta proteins (a/b)	P-loop containing nucleoside triphosphate hydrolases	P-loop containing nucleoside triphosphate hydrolases	RecA protein-like (ATPase-domain)	automated matches	(Bos taurus ) [TaxId: 9913 ],	SCOPe (2.08)
B	d2v7qb3	All alpha proteins	Left-handed superhelix	C-terminal domain of alpha and beta (or A/B) subunits of rotary ATPases	automated matches	automated matches	(Bos taurus ) [TaxId: 9913 ],	SCOPe (2.08)
B	d2v7qb1	All beta proteins	Domain of alpha and beta subunits of F1 ATP synthase-like	N-terminal domain of alpha and beta (or A/B) subunits of rotary ATPases	automated matches	automated matches	(Bos taurus ) [TaxId: 9913 ],	SCOPe (2.08)
B	d2v7qb2	Alpha and beta proteins (a/b)	P-loop containing nucleoside triphosphate hydrolases	P-loop containing nucleoside triphosphate hydrolases	RecA protein-like (ATPase-domain)	automated matches	(Bos taurus ) [TaxId: 9913 ],	SCOPe (2.08)
C	d2v7qc3	All alpha proteins	Left-handed superhelix	C-terminal domain of alpha and beta (or A/B) subunits of rotary ATPases	automated matches	automated matches	(Bos taurus ) [TaxId: 9913 ],	SCOPe (2.08)
C	d2v7qc1	All beta proteins	Domain of alpha and beta subunits of F1 ATP synthase-like	N-terminal domain of alpha and beta (or A/B) subunits of rotary ATPases	automated matches	automated matches	(Bos taurus ) [TaxId: 9913 ],	SCOPe (2.08)
C	d2v7qc2	Alpha and beta proteins (a/b)	P-loop containing nucleoside triphosphate hydrolases	P-loop containing nucleoside triphosphate hydrolases	RecA protein-like (ATPase-domain)	automated matches	(Bos taurus ) [TaxId: 9913 ],	SCOPe (2.08)
D	d2v7qd3	All alpha proteins	Left-handed superhelix	C-terminal domain of alpha and beta (or A/B) subunits of rotary ATPases	C-terminal domain of alpha and beta subunits of F1 ATP synthase	F1 ATP synthase beta subunit, domain 3	(Bos taurus ) [TaxId: 9913 ],	SCOPe (2.08)
D	d2v7qd1	All beta proteins	Domain of alpha and beta subunits of F1 ATP synthase-like	N-terminal domain of alpha and beta (or A/B) subunits of rotary ATPases	N-terminal domain of alpha and beta subunits of F1 ATP synthase	F1 ATP synthase beta subunit, domain 1	(Bos taurus ) [TaxId: 9913 ],	SCOPe (2.08)
D	d2v7qd2	Alpha and beta proteins (a/b)	P-loop containing nucleoside triphosphate hydrolases	P-loop containing nucleoside triphosphate hydrolases	RecA protein-like (ATPase-domain)	Central domain of beta subunit of F1 ATP synthase	(Bos taurus ) [TaxId: 9913 ],	SCOPe (2.08)
F	d2v7qf3	All alpha proteins	Left-handed superhelix	C-terminal domain of alpha and beta (or A/B) subunits of rotary ATPases	C-terminal domain of alpha and beta subunits of F1 ATP synthase	F1 ATP synthase beta subunit, domain 3	(Bos taurus ) [TaxId: 9913 ],	SCOPe (2.08)
F	d2v7qf1	All beta proteins	Domain of alpha and beta subunits of F1 ATP synthase-like	N-terminal domain of alpha and beta (or A/B) subunits of rotary ATPases	N-terminal domain of alpha and beta subunits of F1 ATP synthase	F1 ATP synthase beta subunit, domain 1	(Bos taurus ) [TaxId: 9913 ],	SCOPe (2.08)
F	d2v7qf2	Alpha and beta proteins (a/b)	P-loop containing nucleoside triphosphate hydrolases	P-loop containing nucleoside triphosphate hydrolases	RecA protein-like (ATPase-domain)	Central domain of beta subunit of F1 ATP synthase	(Bos taurus ) [TaxId: 9913 ],	SCOPe (2.08)
E	d2v7qe3	All alpha proteins	Left-handed superhelix	C-terminal domain of alpha and beta (or A/B) subunits of rotary ATPases	C-terminal domain of alpha and beta subunits of F1 ATP synthase	F1 ATP synthase beta subunit, domain 3	(Bos taurus ) [TaxId: 9913 ],	SCOPe (2.08)
E	d2v7qe1	All beta proteins	Domain of alpha and beta subunits of F1 ATP synthase-like	N-terminal domain of alpha and beta (or A/B) subunits of rotary ATPases	N-terminal domain of alpha and beta subunits of F1 ATP synthase	F1 ATP synthase beta subunit, domain 1	(Bos taurus ) [TaxId: 9913 ],	SCOPe (2.08)
E	d2v7qe2	Alpha and beta proteins (a/b)	P-loop containing nucleoside triphosphate hydrolases	P-loop containing nucleoside triphosphate hydrolases	RecA protein-like (ATPase-domain)	Central domain of beta subunit of F1 ATP synthase	(Bos taurus ) [TaxId: 9913 ],	SCOPe (2.08)
G	d2v7qg_	Alpha and beta proteins (a/b)	Pyruvate kinase C-terminal domain-like	ATP synthase (F1-ATPase), gamma subunit	ATP synthase (F1-ATPase), gamma subunit	F1 ATP synthase gamma subunit	(Bos taurus ) [TaxId: 9913 ],	SCOPe (2.08)
H	d2v7qh1	All alpha proteins	Long alpha-hairpin	Epsilon subunit of F1F0-ATP synthase C-terminal domain	Epsilon subunit of F1F0-ATP synthase C-terminal domain	Epsilon subunit of F1F0-ATP synthase C-terminal domain	(Bos taurus ) [TaxId: 9913 ],	SCOPe (2.08)
H	d2v7qh2	All beta proteins	Epsilon subunit of F1F0-ATP synthase N-terminal domain	Epsilon subunit of F1F0-ATP synthase N-terminal domain	Epsilon subunit of F1F0-ATP synthase N-terminal domain	Epsilon subunit of F1F0-ATP synthase N-terminal domain	(Bos taurus ) [TaxId: 9913 ],	SCOPe (2.08)
I	d2v7qi_	All alpha proteins	Non-globular all-alpha subunits of globular proteins	Epsilon subunit of mitochondrial F1F0-ATP synthase	Epsilon subunit of mitochondrial F1F0-ATP synthase	automated matches	(Bos taurus ) [TaxId: 9913 ],	SCOPe (2.08)
J	d2v7qj_	Coiled coil proteins	Antiparallel coiled-coil	F1 ATPase inhibitor, IF1, C-terminal domain	F1 ATPase inhibitor, IF1, C-terminal domain	automated matches	COW (Bos taurus ) [TaxId: 9913 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	ATP synthase alpha/beta C-terminal domain-like	8056868	3000684	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	RecA-like P-loop NTPases	8018243	3002019	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	ATP synthase alpha/beta N-terminal domain-like	8018248	3001034	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	ATP synthase alpha/beta C-terminal domain-like	8056868	3000684	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	ATP synthase alpha/beta N-terminal domain-like	8018248	3001034	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	RecA-like P-loop NTPases	8018243	3002019	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	RecA-like P-loop NTPases	8018243	3002019	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	ATP synthase alpha/beta C-terminal domain-like	8056868	3000684	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	ATP synthase alpha/beta N-terminal domain-like	8018248	3001034	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	RecA-like P-loop NTPases	8018253	3002019	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	ATP synthase alpha/beta N-terminal domain-like	8018258	3001034	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	ATP synthase alpha/beta C-terminal domain-like	8056904	3000684	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	ATP synthase alpha/beta C-terminal domain-like	8056904	3000684	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	RecA-like P-loop NTPases	8018253	3002019	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	ATP synthase alpha/beta N-terminal domain-like	8018258	3001034	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	ATP synthase alpha/beta N-terminal domain-like	8018258	3001034	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	RecA-like P-loop NTPases	8018253	3002019	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	ATP synthase alpha/beta C-terminal domain-like	8056904	3000684	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	ATP synthase gamma subunit-like	8044412	3000451	SCOP2B (2022-06-29)
H	SCOP2 Family	Epsilon subunit of F1F0-ATP synthase N-terminal domain	8024973	4003026	SCOP2 (2022-06-29)
H	SCOP2 Family	Epsilon subunit of F1F0-ATP synthase C-terminal domain	8024971	4000625	SCOP2 (2022-06-29)
H	SCOP2 Superfamily	Epsilon subunit of F1F0-ATP synthase N-terminal domain	8037352	3000182	SCOP2 (2022-06-29)
H	SCOP2 Superfamily	Epsilon subunit of F1F0-ATP synthase C-terminal domain	8037350	3000785	SCOP2 (2022-06-29)
I	SCOP2 Family	epsilon subunit of mitochondrial f1f0-atp synthase	8024974	4001544	SCOP2 (2022-06-29)
I	SCOP2 Superfamily	epsilon subunit of mitochondrial F1F0-ATP synthase	8037353	3001799	SCOP2 (2022-06-29)
J	SCOP2 Family	F1 ATPase inhibitor IF1 C-terminal domain	8024976	4003816	SCOP2 (2022-06-29)
J	SCOP2 Superfamily	F1 ATPase inhibitor IF1 C-terminal domain	8037355	3001557	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	ATP-synt_ab_N	e2v7qA1	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Alanine racemase-C	F: ATP-synt_ab_N	ECOD (1.6)
A	ATP-synt_ab_C	e2v7qA2	A: alpha superhelices	X: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology)	H: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology)	T: C-terminal domain of alpha and beta subunits of F1 ATP synthase	F: ATP-synt_ab_C	ECOD (1.6)
A	ATP-synt_ab	e2v7qA3	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: ATP-synt_ab	ECOD (1.6)
B	ATP-synt_ab_N	e2v7qB1	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Alanine racemase-C	F: ATP-synt_ab_N	ECOD (1.6)
B	ATP-synt_ab_C	e2v7qB2	A: alpha superhelices	X: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology)	H: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology)	T: C-terminal domain of alpha and beta subunits of F1 ATP synthase	F: ATP-synt_ab_C	ECOD (1.6)
B	ATP-synt_ab	e2v7qB3	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: ATP-synt_ab	ECOD (1.6)
C	ATP-synt_ab_N	e2v7qC1	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Alanine racemase-C	F: ATP-synt_ab_N	ECOD (1.6)
C	ATP-synt_ab_C	e2v7qC2	A: alpha superhelices	X: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology)	H: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology)	T: C-terminal domain of alpha and beta subunits of F1 ATP synthase	F: ATP-synt_ab_C	ECOD (1.6)
C	ATP-synt_ab	e2v7qC3	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: ATP-synt_ab	ECOD (1.6)
D	ATP-synt_ab_N	e2v7qD1	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Alanine racemase-C	F: ATP-synt_ab_N	ECOD (1.6)
D	ATP-synt_ab_C	e2v7qD2	A: alpha superhelices	X: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology)	H: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology)	T: C-terminal domain of alpha and beta subunits of F1 ATP synthase	F: ATP-synt_ab_C	ECOD (1.6)
D	ATP-synt_ab	e2v7qD3	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: ATP-synt_ab	ECOD (1.6)
F	ATP-synt_ab_N	e2v7qF1	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Alanine racemase-C	F: ATP-synt_ab_N	ECOD (1.6)
F	ATP-synt_ab_C	e2v7qF2	A: alpha superhelices	X: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology)	H: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology)	T: C-terminal domain of alpha and beta subunits of F1 ATP synthase	F: ATP-synt_ab_C	ECOD (1.6)
F	ATP-synt_ab	e2v7qF3	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: ATP-synt_ab	ECOD (1.6)
E	ATP-synt_ab_N	e2v7qE1	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Alanine racemase-C	F: ATP-synt_ab_N	ECOD (1.6)
E	ATP-synt_ab_C	e2v7qE2	A: alpha superhelices	X: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology)	H: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology)	T: C-terminal domain of alpha and beta subunits of F1 ATP synthase	F: ATP-synt_ab_C	ECOD (1.6)
E	ATP-synt_ab	e2v7qE3	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: ATP-synt_ab	ECOD (1.6)
G	ATP-synt	e2v7qG2	A: a/b three-layered sandwiches	X: ATP synthase (F1-ATPase), gamma subunit (From Topology)	H: ATP synthase (F1-ATPase), gamma subunit (From Topology)	T: ATP synthase (F1-ATPase), gamma subunit	F: ATP-synt	ECOD (1.6)
H	ATP-synt_DE_N	e2v7qH1	A: beta sandwiches	X: Epsilon subunit of F1F0-ATP synthase-N	H: Epsilon subunit of F1F0-ATP synthase-N (From Topology)	T: Epsilon subunit of F1F0-ATP synthase-N	F: ATP-synt_DE_N	ECOD (1.6)
H	KOG1758	e2v7qH2	A: alpha bundles	X: Long alpha-hairpin	H: Epsilon subunit of F1F0-ATP synthase C-terminal domain (From Topology)	T: Epsilon subunit of F1F0-ATP synthase C-terminal domain	F: KOG1758	ECOD (1.6)
I	ATP-synt_Eps	e2v7qI1	A: extended segments	X: Epsilon subunit of mitochondrial F1F0-ATP synthase (From Topology)	H: Epsilon subunit of mitochondrial F1F0-ATP synthase (From Topology)	T: Epsilon subunit of mitochondrial F1F0-ATP synthase	F: ATP-synt_Eps	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.40.30.20	Mainly Beta	Beta Barrel	Elongation Factor Tu (Ef-tu)	domain 3	CATH (4.3.0)
A	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)
A	1.20.150.20	Mainly Alpha	Up-down Bundle	Lysin	ATP synthase alpha/beta chain, C-terminal domain	CATH (4.3.0)
B	2.40.30.20	Mainly Beta	Beta Barrel	Elongation Factor Tu (Ef-tu)	domain 3	CATH (4.3.0)
B	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)
B	1.20.150.20	Mainly Alpha	Up-down Bundle	Lysin	ATP synthase alpha/beta chain, C-terminal domain	CATH (4.3.0)
C	2.40.30.20	Mainly Beta	Beta Barrel	Elongation Factor Tu (Ef-tu)	domain 3	CATH (4.3.0)
C	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)
C	1.20.150.20	Mainly Alpha	Up-down Bundle	Lysin	ATP synthase alpha/beta chain, C-terminal domain	CATH (4.3.0)
D	2.40.10.170	Mainly Beta	Beta Barrel	Thrombin, subunit H		CATH (4.3.0)
D	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)
D	1.10.1140.10	Mainly Alpha	Orthogonal Bundle	Bovine Mitochondrial F1-ATPase, ATP Synthase Beta Chain	Chain D, domain3	CATH (4.3.0)
F	2.40.10.170	Mainly Beta	Beta Barrel	Thrombin, subunit H		CATH (4.3.0)
F	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)
F	1.10.1140.10	Mainly Alpha	Orthogonal Bundle	Bovine Mitochondrial F1-ATPase, ATP Synthase Beta Chain	Chain D, domain3	CATH (4.3.0)
E	2.40.10.170	Mainly Beta	Beta Barrel	Thrombin, subunit H		CATH (4.3.0)
E	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)
E	1.10.1140.10	Mainly Alpha	Orthogonal Bundle	Bovine Mitochondrial F1-ATPase, ATP Synthase Beta Chain	Chain D, domain3	CATH (4.3.0)
G	1.10.287.80	Mainly Alpha	Orthogonal Bundle	Helix Hairpins	ATP synthase, gamma subunit, helix hairpin domain	CATH (4.3.0)
G	3.40.1380.10	Alpha Beta	3-Layer(aba) Sandwich	Pyruvate Kinase	Chain: A, domain 1	CATH (4.3.0)
H	2.60.15.10	Mainly Beta	Sandwich	ATP Synthase	domain 1	CATH (4.3.0)
H	1.20.5.440	Mainly Alpha	Up-down Bundle	Single alpha-helices involved in coiled-coils or other helix-helix interfaces	ATP synthase delta/epsilon subunit, C-terminal domain	CATH (4.3.0)
I	1.10.1620.20	Mainly Alpha	Orthogonal Bundle	Atp Synthase Epsilon Chain	Chain: I	CATH (4.3.0)
J	1.20.5.500	Mainly Alpha	Up-down Bundle	Single alpha-helices involved in coiled-coils or other helix-helix interfaces	Single helix bin	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C	PF00006	ATP synthase alpha/beta family, nucleotide-binding domain (ATP-synt_ab)	ATP synthase alpha/beta family, nucleotide-binding domain	This entry includes the ATP synthase alpha and beta subunits, the ATP synthase associated with flagella and the termination factor Rho.	Domain
A, B, C	PF00306	ATP synthase alpha/beta chain, C terminal domain (ATP-synt_ab_C)	ATP synthase alpha/beta chain, C terminal domain	-	Domain
A, B, C	PF02874	ATP synthase alpha/beta family, beta-barrel domain (ATP-synt_ab_N)	ATP synthase alpha/beta family, beta-barrel domain	This family includes the ATP synthase alpha and beta subunits the ATP synthase associated with flagella.	Domain
D, E, F	PF00006	ATP synthase alpha/beta family, nucleotide-binding domain (ATP-synt_ab)	ATP synthase alpha/beta family, nucleotide-binding domain	This entry includes the ATP synthase alpha and beta subunits, the ATP synthase associated with flagella and the termination factor Rho.	Domain
D, E, F	PF02874	ATP synthase alpha/beta family, beta-barrel domain (ATP-synt_ab_N)	ATP synthase alpha/beta family, beta-barrel domain	This family includes the ATP synthase alpha and beta subunits the ATP synthase associated with flagella.	Domain
G	PF00231	ATP synthase (ATP-synt)	ATP synthase	-	Domain
H	PF02823	ATP synthase, Delta/Epsilon chain, beta-sandwich domain (ATP-synt_DE_N)	ATP synthase, Delta/Epsilon chain, beta-sandwich domain	Part of the ATP synthase CF(1). These subunits are part of the head unit of the ATP synthase. The subunit is called epsilon in bacteria and delta in mitochondria. In bacteria the delta (D) subunit is equivalent to the mitochondrial Oligomycin sensit ...	Part of the ATP synthase CF(1). These subunits are part of the head unit of the ATP synthase. The subunit is called epsilon in bacteria and delta in mitochondria. In bacteria the delta (D) subunit is equivalent to the mitochondrial Oligomycin sensitive subunit, OSCP (Pfam:PF00213).	Domain
H	PF21335	Metazoan delta subunit of F1F0-ATP synthase, C-terminal domain (ATPD_C_metazoa)	Metazoan delta subunit of F1F0-ATP synthase, C-terminal domain	F-type ATPases consist of two structural domains, F1 containing the extramembraneous catalytic core, and F0 which contains the membrane proton channel. This entry includes ATP synthase subunit delta from animals (called epsilon in bacteria or chlorop ...	F-type ATPases consist of two structural domains, F1 containing the extramembraneous catalytic core, and F0 which contains the membrane proton channel. This entry includes ATP synthase subunit delta from animals (called epsilon in bacteria or chloroplast ATPase), which interacts with subunit C from F0 which is important for connecting the rotor of F1 (gamma subunit) to the rotor of F0 C subunit). This entry represents the C-terminal alpha-helical domain which is likely to act as an inhibitor of ATPase activity [1-5].	Domain
I	PF04627	Mitochondrial ATP synthase epsilon chain (ATP-synt_Eps)	Mitochondrial ATP synthase epsilon chain	-	Family
J	PF04568	Mitochondrial ATPase inhibitor, IATP (IATP)	Mitochondrial ATPase inhibitor, IATP	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C	ATP SYNTHASE SUBUNIT ALPHA HEART ISOFORM	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding ADP binding monoatomic cation transmembrane transporter activity proton transmembrane transporter activity monoatomic ion channel activity proton channel activity proton-transporting ATP synthase activity, rotational mechanism monoatomic cation channel activity passive transmembrane transporter activity inorganic molecular entity transmembrane transporter activity inorganic cation transmembrane transporter activity channel activity monoatomic ion transmembrane transporter activity transporter activity transmembrane transporter activity catalytic activity ligase activity	ribose phosphate metabolic process ATP metabolic process ATP biosynthetic process nucleotide biosynthetic process organonitrogen compound biosynthetic process carbohydrate derivative metabolic process purine ribonucleotide biosynthetic process purine ribonucleoside triphosphate biosynthetic process proton motive force-driven ATP synthesis nucleobase-containing compound metabolic process ribonucleotide biosynthetic process purine nucleotide metabolic process organic substance metabolic process ribonucleotide metabolic process purine nucleoside triphosphate biosynthetic process ribose phosphate metabolic process ATP metabolic process ATP biosynthetic process nucleotide biosynthetic process organonitrogen compound biosynthetic process carbohydrate derivative metabolic process purine ribonucleotide biosynthetic process purine ribonucleoside triphosphate biosynthetic process proton motive force-driven ATP synthesis nucleobase-containing compound metabolic process ribonucleotide biosynthetic process purine nucleotide metabolic process organic substance metabolic process ribonucleotide metabolic process purine nucleoside triphosphate biosynthetic process nucleobase-containing small molecule metabolic process purine-containing compound biosynthetic process purine ribonucleoside triphosphate metabolic process phosphate-containing compound metabolic process organic substance biosynthetic process small molecule metabolic process phosphorus metabolic process ribose phosphate biosynthetic process ribonucleoside triphosphate metabolic process nucleoside phosphate metabolic process carbohydrate derivative biosynthetic process purine nucleoside triphosphate metabolic process organonitrogen compound metabolic process nucleoside triphosphate biosynthetic process cellular metabolic process primary metabolic process nucleotide metabolic process nucleobase-containing compound biosynthetic process ribonucleoside triphosphate biosynthetic process purine-containing compound metabolic process organic cyclic compound metabolic process biosynthetic process organophosphate metabolic process organophosphate biosynthetic process organic cyclic compound biosynthetic process nucleoside phosphate biosynthetic process metabolic process cellular process nucleoside triphosphate metabolic process purine ribonucleotide metabolic process purine nucleotide biosynthetic process	membrane-bounded organelle protein-containing complex ATPase complex intracellular anatomical structure mitochondrial membrane organelle inner membrane mitochondrion membrane protein complex intracellular organelle organelle envelope proton-transporting two-sector ATPase complex proton-transporting two-sector ATPase complex, catalytic domain proton-transporting ATP synthase complex, catalytic core F(1) mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1) membrane-bounded organelle protein-containing complex ATPase complex intracellular anatomical structure mitochondrial membrane organelle inner membrane mitochondrion membrane protein complex intracellular organelle organelle envelope proton-transporting two-sector ATPase complex proton-transporting two-sector ATPase complex, catalytic domain proton-transporting ATP synthase complex, catalytic core F(1) mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1) mitochondrial proton-transporting ATP synthase, catalytic core mitochondrial protein-containing complex proton-transporting ATP synthase, catalytic core catalytic complex proton-transporting ATP synthase complex membrane cellular anatomical entity intracellular membrane-bounded organelle mitochondrial inner membrane mitochondrial proton-transporting ATP synthase complex inner mitochondrial membrane protein complex organelle mitochondrial envelope cytoplasm organelle membrane cell periphery plasma membrane
D, E, F	ATP SYNTHASE SUBUNIT BETA	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding monoatomic cation transmembrane transporter activity proton transmembrane transporter activity primary active transmembrane transporter activity ATPase-coupled transmembrane transporter activity proton-transporting ATPase activity, rotational mechanism ATPase-coupled monoatomic cation transmembrane transporter activity ATP-dependent activity active monoatomic ion transmembrane transporter activity ATPase-coupled ion transmembrane transporter activity active transmembrane transporter activity ATPase activity, coupled to transmembrane movement of ions, rotational mechanism inorganic molecular entity transmembrane transporter activity inorganic cation transmembrane transporter activity monoatomic ion transmembrane transporter activity transporter activity transmembrane transporter activity pyrophosphatase activity ATP hydrolysis activity ribonucleoside triphosphate phosphatase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides hydrolase activity hydrolase activity, acting on acid anhydrides catalytic activity monoatomic ion channel activity proton channel activity proton-transporting ATP synthase activity, rotational mechanism monoatomic cation channel activity passive transmembrane transporter activity channel activity ligase activity	aerobic respiration oxidative phosphorylation nucleotide biosynthetic process organonitrogen compound biosynthetic process carbohydrate derivative metabolic process purine ribonucleotide biosynthetic process purine ribonucleoside triphosphate biosynthetic process nucleobase-containing compound metabolic process ribonucleotide biosynthetic process purine nucleoside triphosphate biosynthetic process phosphate-containing compound metabolic process organic substance biosynthetic process small molecule metabolic process phosphorus metabolic process aerobic respiration oxidative phosphorylation nucleotide biosynthetic process organonitrogen compound biosynthetic process carbohydrate derivative metabolic process purine ribonucleotide biosynthetic process purine ribonucleoside triphosphate biosynthetic process nucleobase-containing compound metabolic process ribonucleotide biosynthetic process purine nucleoside triphosphate biosynthetic process phosphate-containing compound metabolic process organic substance biosynthetic process small molecule metabolic process phosphorus metabolic process ribose phosphate biosynthetic process nucleoside phosphate metabolic process cellular metabolic process primary metabolic process nucleotide metabolic process ribonucleoside triphosphate biosynthetic process organic cyclic compound metabolic process biosynthetic process organophosphate biosynthetic process organic cyclic compound biosynthetic process nucleoside phosphate biosynthetic process proton motive force-driven mitochondrial ATP synthesis metabolic process nucleoside triphosphate metabolic process purine ribonucleotide metabolic process purine nucleotide biosynthetic process ribose phosphate metabolic process cellular respiration ATP metabolic process energy derivation by oxidation of organic compounds ATP biosynthetic process proton motive force-driven ATP synthesis purine nucleotide metabolic process organic substance metabolic process ribonucleotide metabolic process nucleobase-containing small molecule metabolic process purine-containing compound biosynthetic process purine ribonucleoside triphosphate metabolic process ribonucleoside triphosphate metabolic process carbohydrate derivative biosynthetic process purine nucleoside triphosphate metabolic process organonitrogen compound metabolic process nucleoside triphosphate biosynthetic process generation of precursor metabolites and energy nucleobase-containing compound biosynthetic process purine-containing compound metabolic process organophosphate metabolic process cellular process	protein-containing complex ATPase complex intracellular anatomical structure catalytic complex proton-transporting ATP synthase complex membrane membrane protein complex cellular anatomical entity proton-transporting two-sector ATPase complex proton-transporting two-sector ATPase complex, catalytic domain proton-transporting ATP synthase complex, catalytic core F(1) membrane-bounded organelle mitochondrial membrane organelle inner membrane protein-containing complex ATPase complex intracellular anatomical structure catalytic complex proton-transporting ATP synthase complex membrane membrane protein complex cellular anatomical entity proton-transporting two-sector ATPase complex proton-transporting two-sector ATPase complex, catalytic domain proton-transporting ATP synthase complex, catalytic core F(1) membrane-bounded organelle mitochondrial membrane organelle inner membrane mitochondrion intracellular organelle organelle envelope mitochondrial protein-containing complex intracellular membrane-bounded organelle mitochondrial inner membrane mitochondrial proton-transporting ATP synthase complex inner mitochondrial membrane protein complex organelle mitochondrial envelope cytoplasm organelle membrane
G	ATP SYNTHASE GAMMA CHAIN	monoatomic cation transmembrane transporter activity proton transmembrane transporter activity monoatomic ion channel activity proton channel activity proton-transporting ATP synthase activity, rotational mechanism monoatomic cation channel activity passive transmembrane transporter activity inorganic molecular entity transmembrane transporter activity inorganic cation transmembrane transporter activity channel activity monoatomic ion transmembrane transporter activity transporter activity transmembrane transporter activity catalytic activity monoatomic cation transmembrane transporter activity proton transmembrane transporter activity monoatomic ion channel activity proton channel activity proton-transporting ATP synthase activity, rotational mechanism monoatomic cation channel activity passive transmembrane transporter activity inorganic molecular entity transmembrane transporter activity inorganic cation transmembrane transporter activity channel activity monoatomic ion transmembrane transporter activity transporter activity transmembrane transporter activity catalytic activity ligase activity	aerobic respiration oxidative phosphorylation nucleotide biosynthetic process organonitrogen compound biosynthetic process carbohydrate derivative metabolic process purine ribonucleotide biosynthetic process purine ribonucleoside triphosphate biosynthetic process nucleobase-containing compound metabolic process ribonucleotide biosynthetic process purine nucleoside triphosphate biosynthetic process phosphate-containing compound metabolic process organic substance biosynthetic process small molecule metabolic process phosphorus metabolic process aerobic respiration oxidative phosphorylation nucleotide biosynthetic process organonitrogen compound biosynthetic process carbohydrate derivative metabolic process purine ribonucleotide biosynthetic process purine ribonucleoside triphosphate biosynthetic process nucleobase-containing compound metabolic process ribonucleotide biosynthetic process purine nucleoside triphosphate biosynthetic process phosphate-containing compound metabolic process organic substance biosynthetic process small molecule metabolic process phosphorus metabolic process ribose phosphate biosynthetic process nucleoside phosphate metabolic process cellular metabolic process primary metabolic process nucleotide metabolic process ribonucleoside triphosphate biosynthetic process organic cyclic compound metabolic process biosynthetic process organophosphate biosynthetic process organic cyclic compound biosynthetic process nucleoside phosphate biosynthetic process proton motive force-driven mitochondrial ATP synthesis metabolic process nucleoside triphosphate metabolic process purine ribonucleotide metabolic process purine nucleotide biosynthetic process ribose phosphate metabolic process cellular respiration ATP metabolic process energy derivation by oxidation of organic compounds ATP biosynthetic process proton motive force-driven ATP synthesis purine nucleotide metabolic process organic substance metabolic process ribonucleotide metabolic process nucleobase-containing small molecule metabolic process purine-containing compound biosynthetic process purine ribonucleoside triphosphate metabolic process ribonucleoside triphosphate metabolic process carbohydrate derivative biosynthetic process purine nucleoside triphosphate metabolic process organonitrogen compound metabolic process nucleoside triphosphate biosynthetic process generation of precursor metabolites and energy nucleobase-containing compound biosynthetic process purine-containing compound metabolic process organophosphate metabolic process cellular process	membrane-bounded organelle protein-containing complex ATPase complex intracellular anatomical structure mitochondrial membrane organelle inner membrane mitochondrion membrane protein complex intracellular organelle organelle envelope proton-transporting two-sector ATPase complex mitochondrial protein-containing complex catalytic complex membrane membrane-bounded organelle protein-containing complex ATPase complex intracellular anatomical structure mitochondrial membrane organelle inner membrane mitochondrion membrane protein complex intracellular organelle organelle envelope proton-transporting two-sector ATPase complex mitochondrial protein-containing complex catalytic complex membrane proton-transporting ATP synthase complex cellular anatomical entity intracellular membrane-bounded organelle mitochondrial inner membrane mitochondrial proton-transporting ATP synthase complex inner mitochondrial membrane protein complex organelle mitochondrial envelope cytoplasm organelle membrane proton-transporting two-sector ATPase complex, catalytic domain proton-transporting ATP synthase complex, catalytic core F(1) mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)
H	ATP SYNTHASE DELTA CHAIN	monoatomic cation transmembrane transporter activity proton transmembrane transporter activity inorganic molecular entity transmembrane transporter activity inorganic cation transmembrane transporter activity monoatomic ion transmembrane transporter activity transporter activity transmembrane transporter activity monoatomic ion channel activity proton channel activity proton-transporting ATP synthase activity, rotational mechanism monoatomic cation channel activity passive transmembrane transporter activity channel activity catalytic activity monoatomic cation transmembrane transporter activity proton transmembrane transporter activity inorganic molecular entity transmembrane transporter activity inorganic cation transmembrane transporter activity monoatomic ion transmembrane transporter activity transporter activity transmembrane transporter activity monoatomic ion channel activity proton channel activity proton-transporting ATP synthase activity, rotational mechanism monoatomic cation channel activity passive transmembrane transporter activity channel activity catalytic activity ligase activity	transport proton transmembrane transport monoatomic ion transmembrane transport inorganic ion transmembrane transport establishment of localization inorganic cation transmembrane transport transmembrane transport monoatomic cation transmembrane transport localization monoatomic ion transport cellular process monoatomic cation transport aerobic respiration oxidative phosphorylation transport proton transmembrane transport monoatomic ion transmembrane transport inorganic ion transmembrane transport establishment of localization inorganic cation transmembrane transport transmembrane transport monoatomic cation transmembrane transport localization monoatomic ion transport cellular process monoatomic cation transport aerobic respiration oxidative phosphorylation nucleotide biosynthetic process organonitrogen compound biosynthetic process carbohydrate derivative metabolic process purine ribonucleotide biosynthetic process purine ribonucleoside triphosphate biosynthetic process nucleobase-containing compound metabolic process ribonucleotide biosynthetic process purine nucleoside triphosphate biosynthetic process phosphate-containing compound metabolic process organic substance biosynthetic process small molecule metabolic process phosphorus metabolic process ribose phosphate biosynthetic process nucleoside phosphate metabolic process cellular metabolic process primary metabolic process nucleotide metabolic process ribonucleoside triphosphate biosynthetic process organic cyclic compound metabolic process biosynthetic process organophosphate biosynthetic process organic cyclic compound biosynthetic process nucleoside phosphate biosynthetic process proton motive force-driven mitochondrial ATP synthesis metabolic process nucleoside triphosphate metabolic process purine ribonucleotide metabolic process purine nucleotide biosynthetic process ribose phosphate metabolic process cellular respiration ATP metabolic process energy derivation by oxidation of organic compounds ATP biosynthetic process proton motive force-driven ATP synthesis purine nucleotide metabolic process organic substance metabolic process ribonucleotide metabolic process nucleobase-containing small molecule metabolic process purine-containing compound biosynthetic process purine ribonucleoside triphosphate metabolic process ribonucleoside triphosphate metabolic process carbohydrate derivative biosynthetic process purine nucleoside triphosphate metabolic process organonitrogen compound metabolic process nucleoside triphosphate biosynthetic process generation of precursor metabolites and energy nucleobase-containing compound biosynthetic process purine-containing compound metabolic process organophosphate metabolic process protein-containing complex organization cellular component organization cellular component biogenesis organelle organization cellular component assembly proton-transporting ATP synthase complex assembly mitochondrial proton-transporting ATP synthase complex assembly proton-transporting two-sector ATPase complex assembly protein-containing complex assembly cellular component organization or biogenesis mitochondrion organization	membrane-bounded organelle intracellular organelle organelle envelope intracellular anatomical structure mitochondrion mitochondrial envelope organelle cellular anatomical entity cytoplasm intracellular membrane-bounded organelle protein-containing complex ATPase complex mitochondrial membrane organelle inner membrane membrane-bounded organelle intracellular organelle organelle envelope intracellular anatomical structure mitochondrion mitochondrial envelope organelle cellular anatomical entity cytoplasm intracellular membrane-bounded organelle protein-containing complex ATPase complex mitochondrial membrane organelle inner membrane membrane protein complex proton-transporting two-sector ATPase complex mitochondrial protein-containing complex catalytic complex membrane proton-transporting ATP synthase complex mitochondrial inner membrane mitochondrial proton-transporting ATP synthase complex inner mitochondrial membrane protein complex organelle membrane proton-transporting two-sector ATPase complex, catalytic domain proton-transporting ATP synthase complex, catalytic core F(1) mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)
I	ATP SYNTHASE EPSILON CHAIN	monoatomic cation transmembrane transporter activity proton transmembrane transporter activity monoatomic ion channel activity proton channel activity proton-transporting ATP synthase activity, rotational mechanism monoatomic cation channel activity passive transmembrane transporter activity inorganic molecular entity transmembrane transporter activity inorganic cation transmembrane transporter activity channel activity monoatomic ion transmembrane transporter activity transporter activity transmembrane transporter activity catalytic activity monoatomic cation transmembrane transporter activity proton transmembrane transporter activity monoatomic ion channel activity proton channel activity proton-transporting ATP synthase activity, rotational mechanism monoatomic cation channel activity passive transmembrane transporter activity inorganic molecular entity transmembrane transporter activity inorganic cation transmembrane transporter activity channel activity monoatomic ion transmembrane transporter activity transporter activity transmembrane transporter activity catalytic activity ligase activity	aerobic respiration oxidative phosphorylation nucleotide biosynthetic process organonitrogen compound biosynthetic process carbohydrate derivative metabolic process purine ribonucleotide biosynthetic process purine ribonucleoside triphosphate biosynthetic process nucleobase-containing compound metabolic process ribonucleotide biosynthetic process purine nucleoside triphosphate biosynthetic process phosphate-containing compound metabolic process organic substance biosynthetic process small molecule metabolic process phosphorus metabolic process aerobic respiration oxidative phosphorylation nucleotide biosynthetic process organonitrogen compound biosynthetic process carbohydrate derivative metabolic process purine ribonucleotide biosynthetic process purine ribonucleoside triphosphate biosynthetic process nucleobase-containing compound metabolic process ribonucleotide biosynthetic process purine nucleoside triphosphate biosynthetic process phosphate-containing compound metabolic process organic substance biosynthetic process small molecule metabolic process phosphorus metabolic process ribose phosphate biosynthetic process nucleoside phosphate metabolic process cellular metabolic process primary metabolic process nucleotide metabolic process ribonucleoside triphosphate biosynthetic process organic cyclic compound metabolic process biosynthetic process organophosphate biosynthetic process organic cyclic compound biosynthetic process nucleoside phosphate biosynthetic process proton motive force-driven mitochondrial ATP synthesis metabolic process nucleoside triphosphate metabolic process purine ribonucleotide metabolic process purine nucleotide biosynthetic process ribose phosphate metabolic process cellular respiration ATP metabolic process energy derivation by oxidation of organic compounds ATP biosynthetic process proton motive force-driven ATP synthesis purine nucleotide metabolic process organic substance metabolic process ribonucleotide metabolic process nucleobase-containing small molecule metabolic process purine-containing compound biosynthetic process purine ribonucleoside triphosphate metabolic process ribonucleoside triphosphate metabolic process carbohydrate derivative biosynthetic process purine nucleoside triphosphate metabolic process organonitrogen compound metabolic process nucleoside triphosphate biosynthetic process generation of precursor metabolites and energy nucleobase-containing compound biosynthetic process purine-containing compound metabolic process organophosphate metabolic process cellular process	membrane-bounded organelle mitochondrial membrane intracellular anatomical structure organelle inner membrane mitochondrion membrane cellular anatomical entity intracellular membrane-bounded organelle mitochondrial inner membrane intracellular organelle organelle envelope mitochondrial envelope organelle cytoplasm membrane-bounded organelle mitochondrial membrane intracellular anatomical structure organelle inner membrane mitochondrion membrane cellular anatomical entity intracellular membrane-bounded organelle mitochondrial inner membrane intracellular organelle organelle envelope mitochondrial envelope organelle cytoplasm organelle membrane protein-containing complex ATPase complex membrane protein complex proton-transporting two-sector ATPase complex mitochondrial protein-containing complex catalytic complex proton-transporting ATP synthase complex mitochondrial proton-transporting ATP synthase complex inner mitochondrial membrane protein complex proton-transporting two-sector ATPase complex, catalytic domain proton-transporting ATP synthase complex, catalytic core F(1) mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)
J	ATPASE INHIBITOR	identical protein binding protein binding binding protein homodimerization activity protein dimerization activity angiostatin binding calmodulin binding molecular function inhibitor activity molecular function regulator activity ATPase inhibitor activity ATPase regulator activity structural molecule activity ATPase binding enzyme binding	developmental process multicellular organismal process cellular developmental process homeostatic process hemopoiesis cell development erythrocyte differentiation multicellular organismal-level homeostasis myeloid cell differentiation immune system process cell differentiation anatomical structure development homeostasis of number of cells cellular process developmental process multicellular organismal process cellular developmental process homeostatic process hemopoiesis cell development erythrocyte differentiation multicellular organismal-level homeostasis myeloid cell differentiation immune system process cell differentiation anatomical structure development homeostasis of number of cells cellular process myeloid cell homeostasis erythrocyte homeostasis protein-containing complex organization protein homotetramerization cellular component organization cellular component biogenesis cellular component assembly protein complex oligomerization protein tetramerization protein-containing complex assembly protein homooligomerization cellular component organization or biogenesis pigment metabolic process heme metabolic process porphyrin-containing compound biosynthetic process organonitrogen compound metabolic process tetrapyrrole metabolic process heme biosynthetic process organonitrogen compound biosynthetic process pigment biosynthetic process organic cyclic compound metabolic process organic substance metabolic process tetrapyrrole biosynthetic process biosynthetic process organic cyclic compound biosynthetic process organic substance biosynthetic process metabolic process porphyrin-containing compound metabolic process negative regulation of cell population proliferation regulation of biological process cell population proliferation regulation of cellular process endothelial cell proliferation biological regulation negative regulation of biological process negative regulation of endothelial cell proliferation regulation of endothelial cell proliferation regulation of cell population proliferation negative regulation of cellular process regulation of epithelial cell proliferation epithelial cell proliferation negative regulation of epithelial cell proliferation negative regulation of hydrolase activity regulation of molecular function regulation of catalytic activity regulation of hydrolase activity negative regulation of molecular function negative regulation of catalytic activity	membrane-bounded organelle intracellular organelle intracellular anatomical structure mitochondrion organelle cytoplasm cellular anatomical entity intracellular membrane-bounded organelle cell surface protein-containing complex ATPase complex mitochondrial membrane organelle inner membrane membrane protein complex membrane-bounded organelle intracellular organelle intracellular anatomical structure mitochondrion organelle cytoplasm cellular anatomical entity intracellular membrane-bounded organelle cell surface protein-containing complex ATPase complex mitochondrial membrane organelle inner membrane membrane protein complex organelle envelope proton-transporting two-sector ATPase complex mitochondrial protein-containing complex catalytic complex membrane proton-transporting ATP synthase complex mitochondrial inner membrane mitochondrial proton-transporting ATP synthase complex inner mitochondrial membrane protein complex mitochondrial envelope organelle membrane

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C	IPR038376	ATP synthase, alpha subunit, C-terminal domain superfamily	Homologous Superfamily
A, B, C	IPR004100	ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain	Domain
A, B, C	IPR033732	ATP synthase, F1 complex, alpha subunit nucleotide-binding domain	Domain
A, B, C	IPR036121	ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily	Homologous Superfamily
A, B, C	IPR023366	ATP synthase subunit alpha, N-terminal domain-like superfamily	Homologous Superfamily
A, B, C	IPR000793	ATP synthase, alpha subunit, C-terminal	Domain
A, B, C	IPR020003	ATPase, alpha/beta subunit, nucleotide-binding domain, active site	Active Site
A, B, C	IPR000194	ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain	Domain
A, B, C	IPR005294	ATP synthase, F1 complex, alpha subunit	Family
A, B, C	IPR027417	P-loop containing nucleoside triphosphate hydrolase	Homologous Superfamily
D, E, F	IPR004100	ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain	Domain
D, E, F	IPR024034	ATPase, F1/V1 complex, beta/alpha subunit, C-terminal	Homologous Superfamily
D, E, F	IPR036121	ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily	Homologous Superfamily
D, E, F	IPR020003	ATPase, alpha/beta subunit, nucleotide-binding domain, active site	Active Site
D, E, F	IPR000194	ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain	Domain
D, E, F	IPR003593	AAA+ ATPase domain	Domain
D, E, F	IPR005722	ATP synthase, F1 complex, beta subunit	Family
D, E, F	IPR027417	P-loop containing nucleoside triphosphate hydrolase	Homologous Superfamily
G	IPR023632	ATP synthase, F1 complex, gamma subunit conserved site	Conserved Site
G	IPR000131	ATP synthase, F1 complex, gamma subunit	Family
G	IPR035968	ATP synthase, F1 complex, gamma subunit superfamily	Homologous Superfamily
H	IPR036794	ATP synthase delta/epsilon subunit, C-terminal domain superfamily	Homologous Superfamily
H	IPR020546	ATP synthase, F1 complex, delta/epsilon subunit, N-terminal	Domain
H	IPR001469	ATP synthase, F1 complex, delta/epsilon subunit	Family
H	IPR036771	F0F1 ATP synthase delta/epsilon subunit, N-terminal	Homologous Superfamily
H	IPR048937	F1F0-ATP synthase delta subunit, C-terminal domain, metazoan	Domain
I	IPR036742	ATP synthase, F1 complex, epsilon subunit superfamily, mitochondrial	Homologous Superfamily
I	IPR006721	ATP synthase, F1 complex, epsilon subunit, mitochondrial	Family
J	IPR007648	Mitochondrial ATPase inhibitor	Family