2QHB

Crystal structure of NgTRF complexed with telomeric DNA

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
E [auth A]	d2qhba_	All alpha proteins	DNA/RNA-binding 3-helical bundle	Homeodomain-like	Myb/SANT domain	Telomere binding protein TBP1	Tobacco (Nicotiana glutinosa ) [TaxId: 35889 ],	SCOPe (2.08)
F [auth B]	d2qhbb_	All alpha proteins	DNA/RNA-binding 3-helical bundle	Homeodomain-like	Myb/SANT domain	Telomere binding protein TBP1	Tobacco (Nicotiana glutinosa ) [TaxId: 35889 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
E [auth A]	SCOP2B Superfamily	Homeodomain-like	8087318	3000001	SCOP2B (2022-06-29)
F [auth B]	SCOP2B Superfamily	Homeodomain-like	8087318	3000001	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
E [auth A]	PF00249	e2qhbA1	A: alpha arrays	X: HTH	H: HTH	T: tri-helical	F: PF00249	ECOD (1.6)
F [auth B]	PF00249	e2qhbB1	A: alpha arrays	X: HTH	H: HTH	T: tri-helical	F: PF00249	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
E [auth A]	1.10.246.220	Mainly Alpha	Orthogonal Bundle	Serum Albumin	Chain A, Domain 1	CATH (4.3.0)
F [auth B]	1.10.246.220	Mainly Alpha	Orthogonal Bundle	Serum Albumin	Chain A, Domain 1	CATH (4.3.0)

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth C], C [auth E]	5'-D(PTPTPTPAPGPGP*G)-3'	-	-	-
B [auth D], D [auth F]	5'-D(PCPCPCPTPAPAP*A)-3'	-	-	-
E [auth A], F [auth B]	Telomere binding protein TBP1	DNA binding sequence-specific DNA binding sequence-specific double-stranded DNA binding transcription cis-regulatory region binding binding double-stranded DNA binding organic cyclic compound binding nucleic acid binding transcription regulatory region nucleic acid binding telomeric DNA binding	icosanoid metabolic process fatty acid metabolic process oxoacid metabolic process cellular metabolic process carboxylic acid metabolic process primary metabolic process organic acid metabolic process organic substance metabolic process cellular lipid metabolic process small molecule metabolic process metabolic process cellular process lipoxygenase pathway monocarboxylic acid metabolic process icosanoid metabolic process fatty acid metabolic process oxoacid metabolic process cellular metabolic process carboxylic acid metabolic process primary metabolic process organic acid metabolic process organic substance metabolic process cellular lipid metabolic process small molecule metabolic process metabolic process cellular process lipoxygenase pathway monocarboxylic acid metabolic process green leaf volatile biosynthetic process lipid metabolic process regulation of cellular process cellular biosynthetic process RNA metabolic process regulation of primary metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process DNA-templated transcription regulation of RNA metabolic process organic substance biosynthetic process regulation of nucleobase-containing compound metabolic process regulation of RNA biosynthetic process regulation of biosynthetic process regulation of biological process biological regulation regulation of cellular metabolic process regulation of macromolecule metabolic process nucleobase-containing compound biosynthetic process gene expression macromolecule biosynthetic process nucleic acid metabolic process regulation of cellular biosynthetic process organic cyclic compound metabolic process regulation of gene expression biosynthetic process organic cyclic compound biosynthetic process regulation of macromolecule biosynthetic process regulation of DNA-templated transcription macromolecule metabolic process regulation of metabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
E [auth A], F [auth B]	IPR001005	SANT/Myb domain	Domain
E [auth A], F [auth B]	IPR017930	Myb domain	Domain
E [auth A], F [auth B]	IPR031105	Telomere repeat-binding protein, plant	Family
E [auth A], F [auth B]	IPR029071	Ubiquitin-like domain superfamily	Homologous Superfamily
E [auth A], F [auth B]	IPR000626	Ubiquitin-like domain	Domain
E [auth A], F [auth B]	IPR009057	Homeobox-like domain superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.