2QBY
Crystal structure of a heterodimer of Cdc6/Orc1 initiators bound to origin DNA (from S. solfataricus)
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
C [auth A] | Cdc6_C | e2qbyA2 | A: alpha arrays | X: HTH | H: HTH | T: winged | F: Cdc6_C | ECOD (1.6) |
C [auth A] | TIP49_3rd_4 | e2qbyA3 | A: alpha arrays | X: Histone-like | H: Histone-related | T: AAA+ ATPase lid domain | F: TIP49_3rd_4 | ECOD (1.6) |
C [auth A] | AAA | e2qbyA1 | A: a/b three-layered sandwiches | X: P-loop domains-like | H: P-loop domains-related | T: P-loop containing nucleoside triphosphate hydrolases | F: AAA | ECOD (1.6) |
D [auth B] | Cdc6_C | e2qbyB4 | A: alpha arrays | X: HTH | H: HTH | T: winged | F: Cdc6_C | ECOD (1.6) |
D [auth B] | TIP49_3rd_4 | e2qbyB5 | A: alpha arrays | X: Histone-like | H: Histone-related | T: AAA+ ATPase lid domain | F: TIP49_3rd_4 | ECOD (1.6) |
D [auth B] | AAA | e2qbyB3 | A: a/b three-layered sandwiches | X: P-loop domains-like | H: P-loop domains-related | T: P-loop containing nucleoside triphosphate hydrolases | F: AAA | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
C [auth A] | 1.10.8.60 | Mainly Alpha | Orthogonal Bundle | Helicase, Ruva Protein | domain 3 | CATH (4.3.0) |
C [auth A] | 3.40.50.300 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | P-loop containing nucleotide triphosphate hydrolases | CATH (4.3.0) |
C [auth A] | 1.10.10.10 | Mainly Alpha | Orthogonal Bundle | Arc Repressor Mutant, subunit A | Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | CATH (4.3.0) |
D [auth B] | 1.10.8.60 | Mainly Alpha | Orthogonal Bundle | Helicase, Ruva Protein | domain 3 | CATH (4.3.0) |
D [auth B] | 3.40.50.300 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | P-loop containing nucleotide triphosphate hydrolases | CATH (4.3.0) |
D [auth B] | 1.10.10.10 | Mainly Alpha | Orthogonal Bundle | Arc Repressor Mutant, subunit A | Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
C [auth A] | PF09079 | CDC6, C terminal winged helix domain (Cdc6_C) | CDC6, C terminal winged helix domain | The C terminal domain of CDC6 assumes a winged helix fold, with a five alpha-helical bundle (alpha15-alpha19) structure, backed on one side by three beta strands (beta6-beta8). It has been shown that this domain acts as a DNA-localisation factor, how ... | Domain |
C [auth A] | PF13401 | AAA domain (AAA_22) | AAA domain | - | Domain |
D [auth B] | PF09079 | CDC6, C terminal winged helix domain (Cdc6_C) | CDC6, C terminal winged helix domain | The C terminal domain of CDC6 assumes a winged helix fold, with a five alpha-helical bundle (alpha15-alpha19) structure, backed on one side by three beta strands (beta6-beta8). It has been shown that this domain acts as a DNA-localisation factor, how ... | Domain |
D [auth B] | PF13401 | AAA domain (AAA_22) | AAA domain | - | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
C [auth A] | IPR015163 | Cdc6, C-terminal | Domain |
C [auth A] | IPR003593 | AAA+ ATPase domain | Domain |
C [auth A] | IPR036388 | Winged helix-like DNA-binding domain superfamily | Homologous Superfamily |
C [auth A] | IPR014277 | Orc1/Cdc6-type DNA replication protein, archaea | Family |
C [auth A] | IPR036390 | Winged helix DNA-binding domain superfamily | Homologous Superfamily |
C [auth A] | IPR027417 | P-loop containing nucleoside triphosphate hydrolase | Homologous Superfamily |
D [auth B] | IPR015163 | Cdc6, C-terminal | Domain |
D [auth B] | IPR003593 | AAA+ ATPase domain | Domain |
D [auth B] | IPR036388 | Winged helix-like DNA-binding domain superfamily | Homologous Superfamily |
D [auth B] | IPR014277 | Orc1/Cdc6-type DNA replication protein, archaea | Family |
D [auth B] | IPR036390 | Winged helix DNA-binding domain superfamily | Homologous Superfamily |
D [auth B] | IPR027417 | P-loop containing nucleoside triphosphate hydrolase | Homologous Superfamily |