2PYH

Azotobacter vinelandii Mannuronan C-5 epimerase AlgE4 A-module complexed with mannuronan trisaccharide

External Resource: Annotation

Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
B	PF12708	e2pyhB1	A: beta duplicates or obligate multimers	X: Single-stranded right-handed beta-helix	H: Pectin lyase-like (From Topology)	T: Pectin lyase-like	F: PF12708	ECOD (1.6)
A	PF12708	e2pyhA1	A: beta duplicates or obligate multimers	X: Single-stranded right-handed beta-helix	H: Pectin lyase-like (From Topology)	T: Pectin lyase-like	F: PF12708	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
B	2.160.20.10	Mainly Beta	3 Solenoid	Pectate Lyase C-like	Single-stranded right-handed beta-helix, Pectin lyase-like	CATH (4.3.0)
A	2.160.20.10	Mainly Beta	3 Solenoid	Pectate Lyase C-like	Single-stranded right-handed beta-helix, Pectin lyase-like	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF13229	Right handed beta helix region (Beta_helix)	Right handed beta helix region	-	Repeat
A, B	PF12708	Pectate lyase superfamily protein (Pectate_lyase_3)	Pectate lyase superfamily protein	-	Repeat

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Poly(beta-D-mannuronate) C5 epimerase 4	cation binding ion binding binding calcium ion binding metal ion binding small molecule binding isomerase activity catalytic activity	alginic acid biosynthetic process oxoacid metabolic process cellular biosynthetic process organic acid biosynthetic process organic acid metabolic process carboxylic acid biosynthetic process organic substance metabolic process polysaccharide metabolic process organic substance biosynthetic process small molecule metabolic process carbohydrate metabolic process small molecule biosynthetic process polysaccharide biosynthetic process cellular metabolic process alginic acid biosynthetic process oxoacid metabolic process cellular biosynthetic process organic acid biosynthetic process organic acid metabolic process carboxylic acid biosynthetic process organic substance metabolic process polysaccharide metabolic process organic substance biosynthetic process small molecule metabolic process carbohydrate metabolic process small molecule biosynthetic process polysaccharide biosynthetic process cellular metabolic process carbohydrate biosynthetic process carboxylic acid metabolic process alginic acid metabolic process primary metabolic process macromolecule biosynthetic process biosynthetic process metabolic process cellular process macromolecule metabolic process	extracellular region cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR012334	Pectin lyase fold	Homologous Superfamily
A, B	IPR001343	RTX calcium-binding nonapeptide repeat	Repeat
A, B	IPR039448	Right handed beta helix domain	Domain
A, B	IPR024535	Pectate lyase superfamily protein	Domain
A, B	IPR006633	Carbohydrate-binding/sugar hydrolysis domain	Domain
A, B	IPR006626	Parallel beta-helix repeat	Repeat
A, B	IPR018511	Hemolysin-type calcium-binding conserved site	Conserved Site
A, B	IPR011049	Serralysin-like metalloprotease, C-terminal	Homologous Superfamily
A, B	IPR011050	Pectin lyase fold/virulence factor	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.