2POF

Crystal structure of CDP-diacylglycerol pyrophosphatase

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d2pofa1	Alpha and beta proteins (a+b)	HIT-like	HIT-like	CDH-like	CDP-diacylglycerol pyrophosphatase CDH	(Escherichia coli O157:H7 ) [TaxId: 83334 ],	SCOPe (2.08)
B	d2pofb_	Alpha and beta proteins (a+b)	HIT-like	HIT-like	CDH-like	CDP-diacylglycerol pyrophosphatase CDH	(Escherichia coli O157:H7 ) [TaxId: 83334 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	CDH-like	8023513	4002592	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	HIT-like	8035893	3000223	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	HIT-like	8035893	3000223	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	CDH_C	e2pofA2	A: a+b three layers	X: HIT-like	H: HIT-related (From Topology)	T: HIT-related	F: CDH_C	ECOD (1.6)
A	CDH_N	e2pofA1	A: a+b three layers	X: HIT-like	H: HIT-related (From Topology)	T: HIT-related	F: CDH_N	ECOD (1.6)
B	CDH_C	e2pofB1	A: a+b three layers	X: HIT-like	H: HIT-related (From Topology)	T: HIT-related	F: CDH_C	ECOD (1.6)
B	CDH_N	e2pofB2	A: a+b three layers	X: HIT-like	H: HIT-related (From Topology)	T: HIT-related	F: CDH_N	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.30.428.30	Alpha Beta	2-Layer Sandwich	HIT family, subunit A	HIT family - CDH-like	CATH (4.3.0)
B	3.30.428.30	Alpha Beta	2-Layer Sandwich	HIT family, subunit A	HIT family - CDH-like	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF02611	CDP-diacylglycerol pyrophosphatase (CDH)	CDP-diacylglycerol pyrophosphatase	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	CDP-diacylglycerol pyrophosphatase	pyrophosphatase activity CDP-diacylglycerol diphosphatase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides hydrolase activity hydrolase activity, acting on acid anhydrides catalytic activity	catabolic process phospholipid catabolic process glycerophospholipid metabolic process glycerolipid catabolic process organophosphate catabolic process cellular lipid catabolic process cellular catabolic process phospholipid metabolic process organic substance metabolic process CDP-diacylglycerol catabolic process phosphate-containing compound metabolic process phosphorus metabolic process lipid catabolic process CDP-diacylglycerol metabolic process catabolic process phospholipid catabolic process glycerophospholipid metabolic process glycerolipid catabolic process organophosphate catabolic process cellular lipid catabolic process cellular catabolic process phospholipid metabolic process organic substance metabolic process CDP-diacylglycerol catabolic process phosphate-containing compound metabolic process phosphorus metabolic process lipid catabolic process CDP-diacylglycerol metabolic process cellular metabolic process primary metabolic process organophosphate metabolic process cellular lipid metabolic process glycerophospholipid catabolic process metabolic process cellular process glycerolipid metabolic process organic substance catabolic process lipid metabolic process lipid biosynthetic process phospholipid biosynthetic process biosynthetic process organophosphate biosynthetic process organic substance biosynthetic process	cell periphery plasma membrane membrane cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR015993	CDP-diacylglycerol pyrophosphatase, proteobacterial	Family
A, B	IPR036265	HIT-like superfamily	Homologous Superfamily
A, B	IPR003763	CDP-diacylglycerol pyrophosphatase	Family

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.