2NR7

Structural Genomics, the crystal structure of putative secretion activator protein from Porphyromonas gingivalis W83

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d2nr7a1	Alpha and beta proteins (a+b)	Lysozyme-like	Lysozyme-like	NMB1012-like	Putative secretion activator PG0293	(Porphyromonas gingivalis W83 ) [TaxId: 242619 ],	SCOPe (2.08)
A	d2nr7a2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Porphyromonas gingivalis W83 ) [TaxId: 242619 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	NMB1012-like	8022455	4002504	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Lysozyme-like	8034835	3001879	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF05838,PF09374	e2nr7A1	A: a+b complex topology	X: Lysozyme-like (From Homology)	H: Lysozyme-like	T: Lysozyme-like	F: PF05838,PF09374	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.20.141.10	Mainly Alpha	Up-down Bundle	Chitosanase, subunit A	domain 1	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF05838	Glycosyl hydrolase 108 (Glyco_hydro_108)	Glycosyl hydrolase 108	This family acts as a lysozyme (N-acetylmuramidase), EC:3.2.1.17. It contains a conserved EGGY motif near the N-terminus, the glutamic acid within this motif is essential for catalytic activity [1]. In bacteria, it may activate the secretion of large ...	This family acts as a lysozyme (N-acetylmuramidase), EC:3.2.1.17. It contains a conserved EGGY motif near the N-terminus, the glutamic acid within this motif is essential for catalytic activity [1]. In bacteria, it may activate the secretion of large proteins via the breaking and rearrangement of the peptidoglycan layer during secretion [2,3]. It is frequently found at the N-terminus of proteins containing a C-terminal Pfam:PF09374 domain.	Domain
A	PF09374	Predicted Peptidoglycan domain (PG_binding_3)	Predicted Peptidoglycan domain	This family contains a potential peptidoglycan binding domain.	Domain

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR008565	TtsA-like, Glycoside hydrolase family 108 domain	Domain
A	IPR018537	Peptidoglycan binding domain	Domain
A	IPR018247	EF-Hand 1, calcium-binding site	Binding Site
A	IPR023346	Lysozyme-like domain superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.