Annotations: 2N64

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C	SH3 domain-containing kinase-binding protein 1	SH3 domain binding protein binding binding protein domain specific binding ubiquitin protein ligase binding ubiquitin-like protein ligase binding enzyme binding	localization import into cell transport cellular process endocytosis establishment of localization vesicle-mediated transport apoptotic process cell death programmed cell death regulation of biological process signaling biological regulation cell-cell signaling localization import into cell transport cellular process endocytosis establishment of localization vesicle-mediated transport apoptotic process cell death programmed cell death regulation of biological process signaling biological regulation cell-cell signaling cell communication cell migration cell motility developmental process regulation of developmental process regulation of cell shape cell morphogenesis regulation of cell morphogenesis anatomical structure morphogenesis anatomical structure development regulation of biological quality regulation of anatomical structure morphogenesis cellular component organization organelle organization cellular component organization or biogenesis cytoskeleton organization multicellular organismal process regulation of cellular process regulation of leukocyte activation positive regulation of biological process regulation of cell activation lymphocyte activation leukocyte activation positive regulation of lymphocyte activation positive regulation of cell activation regulation of B cell activation positive regulation of leukocyte activation regulation of multicellular organismal process regulation of immune system process positive regulation of immune system process positive regulation of cellular process B cell activation cell activation positive regulation of B cell activation immune system process positive regulation of multicellular organismal process regulation of lymphocyte activation actin cytoskeleton organization actin filament organization actin filament-based process supramolecular fiber organization	anchoring junction cell junction cellular anatomical entity focal adhesion cell-substrate junction cell-cell junction intracellular anatomical structure cytoplasm cytosol cell periphery plasma membrane membrane membrane-bounded organelle intracellular vesicle anchoring junction cell junction cellular anatomical entity focal adhesion cell-substrate junction cell-cell junction intracellular anatomical structure cytoplasm cytosol cell periphery plasma membrane membrane membrane-bounded organelle intracellular vesicle intracellular membrane-bounded organelle intracellular organelle cytoplasmic vesicle organelle vesicle endocytic vesicle cell projection neuron projection plasma membrane bounded cell projection cytoplasmic vesicle membrane vesicle membrane organelle membrane cytoskeleton intracellular non-membrane-bounded organelle non-membrane-bounded organelle synapse

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C	IPR036028	SH3-like domain superfamily	Homologous Superfamily
A, B, C	IPR035771	SH3 domain-containing kinase-binding protein 1, second SH3 domain	Domain
A, B, C	IPR001452	SH3 domain	Domain
A, B, C	IPR035772	SH3 domain-containing kinase-binding protein 1, third SH3 domain	Domain
A, B, C	IPR035770	SH3 domain-containing kinase-binding protein 1, first SH3 domain	Domain

Pharos: Disease Associations Pharos Homepage Annotation

Chains	Drug Target	Associated Disease
A, B, C	Pharos: Q96B97	malignant colon neoplasm osteosarcoma pancreatic intraductal papillary-mucinous carcinoma primitive neuroectodermal tumor acute myeloid leukemia atypical teratoid rhabdoid tumor breast fibroadenoma glioblastoma large cell medulloblastoma malignant glioma non-small cell lung carcinoma ovarian cancer pancreatic intraductal papillary-mucinous neoplasm Sjogren syndrome astrocytic tumor malignant colon neoplasm osteosarcoma pancreatic intraductal papillary-mucinous carcinoma primitive neuroectodermal tumor acute myeloid leukemia atypical teratoid rhabdoid tumor breast fibroadenoma glioblastoma large cell medulloblastoma malignant glioma non-small cell lung carcinoma ovarian cancer pancreatic intraductal papillary-mucinous neoplasm Sjogren syndrome astrocytic tumor benign colon neoplasm colonic neoplasm interstitial cystitis malignant pancreatic neoplasm oligodendroglioma pancreatic ductal adenocarcinoma pancreatic intraductal papillary-mucinous neoplasm with low grade dysplasia tuberculosis atopic eczema breast carcinoma gastric carcinoma invasive ductal breast carcinoma malignant ependymoma medulloblastoma

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.