Annotations: 2MF4

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF00550	e2mf4A1	A: alpha bundles	X: ACP-like	H: Acyl-carrier protein (ACP) (From Topology)	T: Acyl-carrier protein (ACP)	F: PF00550	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.10.1200.10	Mainly Alpha	Orthogonal Bundle	Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein	Chain A	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF00550	Phosphopantetheine attachment site (PP-binding)	Phosphopantetheine attachment site	A 4'-phosphopantetheine prosthetic group is attached through a serine. This prosthetic group acts as a a 'swinging arm' for the attachment of activated fatty acid and amino-acid groups. This domain forms a four helix bundle. This family includes memb ...	A 4'-phosphopantetheine prosthetic group is attached through a serine. This prosthetic group acts as a a 'swinging arm' for the attachment of activated fatty acid and amino-acid groups. This domain forms a four helix bundle. This family includes members not included in Prosite. The inclusion of these members is supported by sequence analysis and functional evidence. The related domain of Swiss:P19828 has the attachment serine replaced by an alanine.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Hybrid polyketide synthase-non ribosomal peptide synthetase	vitamin binding amide binding modified amino acid binding binding phosphopantetheine binding small molecule binding acyltransferase activity 3-oxoacyl-[acyl-carrier-protein] synthase activity acyltransferase activity, transferring groups other than amino-acyl groups transferase activity catalytic activity	organic cyclic compound metabolic process organic substance metabolic process biosynthetic process organic cyclic compound biosynthetic process organic substance biosynthetic process metabolic process amide biosynthetic process amide metabolic process secondary metabolite biosynthetic process cellular biosynthetic process cellular metabolic process cellular process toxin biosynthetic process secondary metabolic process organic cyclic compound metabolic process organic substance metabolic process biosynthetic process organic cyclic compound biosynthetic process organic substance biosynthetic process metabolic process amide biosynthetic process amide metabolic process secondary metabolite biosynthetic process cellular biosynthetic process cellular metabolic process cellular process toxin biosynthetic process secondary metabolic process toxin metabolic process antibiotic metabolic process antibiotic biosynthetic process organonitrogen compound metabolic process organonitrogen compound biosynthetic process fatty acid metabolic process monocarboxylic acid biosynthetic process small molecule biosynthetic process oxoacid metabolic process carboxylic acid metabolic process lipid biosynthetic process primary metabolic process organic acid biosynthetic process organic acid metabolic process fatty acid biosynthetic process carboxylic acid biosynthetic process cellular lipid metabolic process small molecule metabolic process monocarboxylic acid metabolic process lipid metabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR014031	Beta-ketoacyl synthase, C-terminal	Domain
A	IPR006162	Phosphopantetheine attachment site	PTM
A	IPR013217	Methyltransferase type 12	Domain
A	IPR020807	Polyketide synthase, dehydratase domain	Domain
A	IPR014030	Beta-ketoacyl synthase, N-terminal	Domain
A	IPR049552	Polyketide synthase, dehydratase domain, N-terminal	Domain
A	IPR049551	Polyketide synthase, dehydratase domain, C-terminal	Domain
A	IPR020845	AMP-binding, conserved site	Conserved Site
A	IPR023213	Chloramphenicol acetyltransferase-like domain superfamily	Homologous Superfamily
A	IPR013968	Polyketide synthase, ketoreductase domain	Domain
A	IPR020806	Polyketide synthase, phosphopantetheine-binding domain	Domain
A	IPR020841	Polyketide synthase, beta-ketoacyl synthase domain	Domain
A	IPR001242	Condensation domain	Domain
A	IPR036736	ACP-like superfamily	Homologous Superfamily
A	IPR025110	AMP-binding enzyme, C-terminal domain	Domain
A	IPR032821	Polyketide synthase, C-terminal extension	Domain
A	IPR009081	Phosphopantetheine binding ACP domain	Domain
A	IPR029063	S-adenosyl-L-methionine-dependent methyltransferase superfamily	Homologous Superfamily
A	IPR010071	Amino acid adenylation domain	Domain
A	IPR016039	Thiolase-like	Homologous Superfamily
A	IPR045851	AMP-binding enzyme, C-terminal domain superfamily	Homologous Superfamily
A	IPR042099	ANL, N-terminal domain	Homologous Superfamily
A	IPR036291	NAD(P)-binding domain superfamily	Homologous Superfamily
A	IPR018201	Beta-ketoacyl synthase, active site	Active Site
A	IPR000873	AMP-dependent synthetase/ligase domain	Domain
A	IPR042104	Polyketide synthase, dehydratase domain superfamily	Homologous Superfamily