Annotations: 2M0H

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Pulmonary surfactant-associated protein B	-	membrane lipid metabolic process organonitrogen compound metabolic process organic substance metabolic process cellular metabolic process cellular lipid metabolic process sphingolipid metabolic process metabolic process primary metabolic process cellular process lipid metabolic process developmental process anatomical structure morphogenesis animal organ development anatomical structure development membrane lipid metabolic process organonitrogen compound metabolic process organic substance metabolic process cellular metabolic process cellular lipid metabolic process sphingolipid metabolic process metabolic process primary metabolic process cellular process lipid metabolic process developmental process anatomical structure morphogenesis animal organ development anatomical structure development animal organ morphogenesis multicellular organismal process respiratory gaseous exchange by respiratory system	membrane-bounded organelle intracellular anatomical structure intracellular vesicle cellular anatomical entity intracellular membrane-bounded organelle endomembrane system intracellular organelle lamellar body cytoplasmic vesicle organelle secretory granule secretory vesicle cytoplasm vesicle membrane-bounded organelle intracellular anatomical structure intracellular vesicle cellular anatomical entity intracellular membrane-bounded organelle endomembrane system intracellular organelle lamellar body cytoplasmic vesicle organelle secretory granule secretory vesicle cytoplasm vesicle alveolar lamellar body extracellular region multivesicular body lumen endosome membrane-enclosed lumen intracellular organelle lumen organelle lumen late endosome late endosome lumen endosome lumen multivesicular body clathrin-coated endocytic vesicle clathrin-coated vesicle coated vesicle endocytic vesicle lytic vacuole vacuole lysosome organelle subcompartment membrane endoplasmic reticulum subcompartment nuclear outer membrane-endoplasmic reticulum membrane network endoplasmic reticulum organelle membrane endoplasmic reticulum membrane

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR011001	Saposin-like	Homologous Superfamily
A	IPR008373	Saposin	Family
A	IPR007856	Saposin-like type B, region 1	Domain
A	IPR008139	Saposin B type domain	Domain
A	IPR008138	Saposin B type, region 2	Domain
A	IPR003119	Saposin A-type domain	Domain

Pharos: Disease Associations Pharos Homepage Annotation

Chains	Drug Target	Associated Disease
A	Pharos: P07988	neonatal acute respiratory distress due to SP-B deficiency newborn respiratory distress syndrome congenital diaphragmatic hernia lung disease ovarian cancer pulmonary alveolar proteinosis atypical teratoid rhabdoid tumor Diaphragmatic Hernia large cell medulloblastoma lung cancer non-small cell lung carcinoma ovarian carcinoma breast carcinoma glioblastoma lung adenocarcinoma neonatal acute respiratory distress due to SP-B deficiency newborn respiratory distress syndrome congenital diaphragmatic hernia lung disease ovarian cancer pulmonary alveolar proteinosis atypical teratoid rhabdoid tumor Diaphragmatic Hernia large cell medulloblastoma lung cancer non-small cell lung carcinoma ovarian carcinoma breast carcinoma glioblastoma lung adenocarcinoma lung carcinoma osteosarcoma prostate carcinoma respiratory failure heart disease lung benign neoplasm malignant mesothelioma

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.