2LVN
Structure of the gp78 CUE domain
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A [auth C] | PF02845 | e2lvnC1 | A: alpha arrays | X: RuvA-C | H: RuvA-C, UBA, CRAL/TRIO-N, HBS1 (From Topology) | T: RuvA-C, UBA, CRAL/TRIO-N, HBS1 | F: PF02845 | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A [auth C] | 1.10.8.10 | Mainly Alpha | Orthogonal Bundle | Helicase, Ruva Protein | domain 3 | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
A [auth C] | PF02845 | CUE domain (CUE) | CUE domain | CUE domains have been shown to bind ubiquitin [3-4]. It has been suggested that CUE domains are related to Pfam:PF00627 [4] and this has been confirmed by the structure of the domain [5]. CUE domains also occur in two protein of the IL-1 signal trans ... | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
A [auth C] | IPR003892 | Ubiquitin system component CUE | Domain |
A [auth C] | IPR013083 | Zinc finger, RING/FYVE/PHD-type | Homologous Superfamily |
A [auth C] | IPR040675 | E3 ubiquitin-protein ligase AMFR, Ube2g2-binding region | Domain |
A [auth C] | IPR001841 | Zinc finger, RING-type | Domain |
Pharos: Disease Associations Pharos Homepage Annotation
Chains | Drug Target   | Associated Disease |
---|---|---|
A [auth C] | Q9UKV5 | :